Noah Younger
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View article: Development of a Culturally Tailored Educational Tool to Increase Somatic Testing Participation Among Black Men With Metastatic Prostate Cancer
Development of a Culturally Tailored Educational Tool to Increase Somatic Testing Participation Among Black Men With Metastatic Prostate Cancer Open
PURPOSE Black patients with metastatic prostate cancer (mPCa) are less likely to receive somatic testing than their White counterparts. Our objective was to develop a culturally tailored educational tool intended to increase somatic testin…
View article: Identification and Characterization of PLUTO-201, a Novel Long Non-Coding RNA Associated with Poor Outcomes in Prostate Cancer
Identification and Characterization of PLUTO-201, a Novel Long Non-Coding RNA Associated with Poor Outcomes in Prostate Cancer Open
Despite extensive investigation, the factors promoting aggressive prostate cancer are poorly understood. By performing a comprehensive analysis of whole-genome transcriptome data to identify differential expression across 1,567 patients wi…
View article: Supplementary Figure 4. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 4. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Gene Ontology (GO) with Biological processes (BP) on the genes uniquely up- or down-regulated within each subtype
View article: Supplementary Data 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Data 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
List of Differentially expressed genes in the subtypes of mCRPC in comparison with AR+/NE- tumors
View article: Supplementary Figure 3. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 3. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Volcano plots representing the differentially expressed (DE) genes in the mCRPC subtypes compared to AR+/NE- tumors
View article: Supplementary Data 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Data 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
List of enriched motifs identified in the hyper- and hypo-methylated regions of mCRPC subtypes
View article: Supplementary Figure 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Hierarchical clustering analyses of benign, localized, and mCRPC tumors representing the expression of neuroendocrine marker genes (NE), androgen-related genes (AR), and genes related to squamous (SQUAM) differentiation
View article: Supplementary Figure 6. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 6. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Gene expression level of CHD7 among the mCRPC tumors of Beltran et al. cohort
View article: Supplementary Figure 8. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 8. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Gene expression level of Krüppel-like factor (KLF) family among the five mCRPC subtypes
View article: Supplementary Figure 3. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 3. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Volcano plots representing the differentially expressed (DE) genes in the mCRPC subtypes compared to AR+/NE- tumors
View article: Supplementary Table 3. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Table 3. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
ETS family fusions detected in the WCDT samples
View article: Supplementary Table 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Table 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Clinical characteristics of samples in WCDT cohort
View article: Supplementary Figure 6. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 6. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Gene expression level of CHD7 among the mCRPC tumors of Beltran et al. cohort
View article: Supplementary Figure 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Hierarchical clustering and principal component analyses (PCA) on the mCRPC tumors of WCDT cohort.
View article: Supplementary Figure 7. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 7. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
A heatmap representing the enrichment of transcription factors (TF) in hypermethylated regions of different subtypes of the WCDT samples
View article: Supplementary Figure 5. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 5. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Gene expression level of SOX2 among the tumor subtypes of WCDT samples
View article: Supplementary Table 3. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Table 3. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
ETS family fusions detected in the WCDT samples
View article: Supplementary Figure 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Hierarchical clustering and principal component analyses (PCA) on the mCRPC tumors of WCDT cohort.
View article: Supplementary Figure 8. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 8. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Gene expression level of Krüppel-like factor (KLF) family among the five mCRPC subtypes
View article: Supplementary Data 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Data 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
List of Differentially expressed genes in the subtypes of mCRPC in comparison with AR+/NE- tumors
View article: Supplementary Table 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Table 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Molecular Charactersistcs of samples in WCDT cohort
View article: Supplementary Figure 5. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 5. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Gene expression level of SOX2 among the tumor subtypes of WCDT samples
View article: Supplementary Table 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Table 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Molecular Charactersistcs of samples in WCDT cohort
View article: Supplementary Figure 7. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 7. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
A heatmap representing the enrichment of transcription factors (TF) in hypermethylated regions of different subtypes of the WCDT samples
View article: Supplementary Figure 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Hierarchical clustering analyses of benign, localized, and mCRPC tumors representing the expression of neuroendocrine marker genes (NE), androgen-related genes (AR), and genes related to squamous (SQUAM) differentiation
View article: Data from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Data from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Systemic targeted therapy in prostate cancer is primarily focused on ablating androgen signaling. Androgen deprivation therapy and second-generation androgen receptor (AR)-targeted therapy selectively favor the development of treatment-res…
View article: Supplementary Data 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Data 2. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
List of enriched motifs identified in the hyper- and hypo-methylated regions of mCRPC subtypes
View article: Supplementary Table 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Table 1. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Clinical characteristics of samples in WCDT cohort
View article: Supplementary Figure 4. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer
Supplementary Figure 4. from The genomic and epigenomic landscape of double-negative metastatic prostate cancer Open
Gene Ontology (GO) with Biological processes (BP) on the genes uniquely up- or down-regulated within each subtype
View article: Supplementary Figure 3. from The Genomic and Epigenomic Landscape of Double-Negative Metastatic Prostate Cancer
Supplementary Figure 3. from The Genomic and Epigenomic Landscape of Double-Negative Metastatic Prostate Cancer Open
Volcano plots representing the differentially expressed (DE) genes in the mCRPC subtypes compared to AR+/NE- tumors