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View article: Synergistic Effects of Anthocyanin-Enriched Morus alba L. Extract and Vitamin C: Promising Nutraceutical Ingredients in Functional Food Development for Neuroprotection
Synergistic Effects of Anthocyanin-Enriched Morus alba L. Extract and Vitamin C: Promising Nutraceutical Ingredients in Functional Food Development for Neuroprotection Open
Oxidative stress-induced mitochondrial dysfunction and apoptosis are critical factors in the pathogenesis of neurodegenerative diseases. This study investigated the synergistic neuroprotective effects of anthocyanin-enriched Morus alba L. …
View article: Synergistic Antioxidant Effects of C3G-Enriched Oryza sativa L. cv. RD83 Extract and α-Tocopherol Against H2O2-Induced Oxidative Stress in SH-SY5Y Cells
Synergistic Antioxidant Effects of C3G-Enriched Oryza sativa L. cv. RD83 Extract and α-Tocopherol Against H2O2-Induced Oxidative Stress in SH-SY5Y Cells Open
Oxidative stress, which contributes to neuronal cell dysfunction, is a critical factor in the pathogenesis of neurodegenerative diseases. Anthocyanins and α-tocopherol have shown potential in mitigating oxidative damage, and their combinat…
View article: The Neuroprotective Potential of Seed Extract from the Indian Trumpet Tree Against Amyloid Beta-Induced Toxicity in SH-SY5Y Cells
The Neuroprotective Potential of Seed Extract from the Indian Trumpet Tree Against Amyloid Beta-Induced Toxicity in SH-SY5Y Cells Open
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with an unclear etiology. Multiple factors, including oxidative stress and the accumulation of amyloid beta (Aβ) protein in the brain, contribute to neuronal damage. This…
View article: Oroxylum indicum (L.) Leaf Extract Attenuates β-Amyloid-Induced Neurotoxicity in SH-SY5Y Cells
Oroxylum indicum (L.) Leaf Extract Attenuates β-Amyloid-Induced Neurotoxicity in SH-SY5Y Cells Open
Alzheimer’s disease (AD) is characterized by the presence of amyloid-beta (Aβ) plaques, which trigger oxidative stress and neuronal cell death. The present study investigated the neuroprotective effects of Oroxylum indicum (L.) leaf (OIL) …
View article: Synergistic Neuroprotection Through Epigenetic Modulation by Combined Curcumin-Enriched Turmeric Extract and L-Ascorbic Acid in Oxidative Stress-Induced SH-SY5Y Cell Damage
Synergistic Neuroprotection Through Epigenetic Modulation by Combined Curcumin-Enriched Turmeric Extract and L-Ascorbic Acid in Oxidative Stress-Induced SH-SY5Y Cell Damage Open
Epigenetic modulation plays a crucial role in neuroprotection by regulating cellular responses to stress, inflammation, and oxidative damage, particularly in neurodegenerative diseases. Recognizing the therapeutic potential of epigenetic r…
View article: Phytosome-Encapsulated 6-Gingerol- and 6-Shogaol-Enriched Extracts from Zingiber officinale Roscoe Protect Against Oxidative Stress-Induced Neurotoxicity
Phytosome-Encapsulated 6-Gingerol- and 6-Shogaol-Enriched Extracts from Zingiber officinale Roscoe Protect Against Oxidative Stress-Induced Neurotoxicity Open
The rising prevalence of neurodegenerative disorders underscores the urgent need for effective interventions to prevent neuronal cell death. This study evaluates the neuroprotective potential of phytosome-encapsulated 6-gingerol- and 6-sho…
View article: <i>Oroxylum indicum</i> Kurz (L) leaf extract exerted antioxidant and anti-inflammatory effects on LPS-stimulated BV2 microglial cells
<i>Oroxylum indicum</i> Kurz (L) leaf extract exerted antioxidant and anti-inflammatory effects on LPS-stimulated BV2 microglial cells Open
Purpose: To investigate the antioxidant and anti-inflammatory effects of Oroxylum indicum (L.) Kurz leaf extract on lipopolysaccharide (LPS)-activated BV2 microglia. Methods: BV2 cells were treated with LPS for 24 h in the presence or abse…
View article: An anthocyanin-rich extract from Zea mays L. var. ceratina alleviates neuronal cell death caused by hydrogen peroxide-induced cytotoxicity in SH-SY5Y cells
An anthocyanin-rich extract from Zea mays L. var. ceratina alleviates neuronal cell death caused by hydrogen peroxide-induced cytotoxicity in SH-SY5Y cells Open
View article: Neuroprotective Potential of <i>Thunbergia laurifolia</i> Lindl. Leaf Extracts against Beta Amyloid-induced Neurotoxicity: An <i>in vitro</i> Model of Alzheimer’s Disease
Neuroprotective Potential of <i>Thunbergia laurifolia</i> Lindl. Leaf Extracts against Beta Amyloid-induced Neurotoxicity: An <i>in vitro</i> Model of Alzheimer’s Disease Open
Background Beta-amyloid peptide (Aβ) induces oxidative stress, contributing to Alzheimer’s disease (AD) initiation and progression. This study aims to explore Thunbergia laurifolia ( T. laurifolia) leaf extract’s protective effects on Aβ25…
View article: Crude extracts of <i>Momordica cochinchinensis</i> (Lour.) Spreng exerts antioxidant and anti-neuroinflammatory properties in LPS-stimulated BV2 microglia
Crude extracts of <i>Momordica cochinchinensis</i> (Lour.) Spreng exerts antioxidant and anti-neuroinflammatory properties in LPS-stimulated BV2 microglia Open
Purpose: To evaluate the antioxidant and anti-neuroinflammatory properties of the leaves, seeds and pulp of Momordica cochinchinensis Spreng (commonly known as Gac) in vitro and in lipopolysaccharide (LPS)-activated BV2 microglial cells.
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View article: The neuroprotective effects of the combined extract of mulberry fruit and mulberry leaf against hydrogen peroxide-induced cytotoxicity in SH-SY5Y Cells
The neuroprotective effects of the combined extract of mulberry fruit and mulberry leaf against hydrogen peroxide-induced cytotoxicity in SH-SY5Y Cells Open
View article: Oroxylum indicum (L.) Fruits Extract Suppresses BV2 Microglial Activation Through Inhibition of NF-κB and Akt/ERK1/2 Pathway
Oroxylum indicum (L.) Fruits Extract Suppresses BV2 Microglial Activation Through Inhibition of NF-κB and Akt/ERK1/2 Pathway Open
Background and Objective: Oroxylum indicum (L.) Kurz, a plant distributed throughout India and Southeastern Asia.Different parts of the plant applied traditionally for the treatments.The present study attempted to elucidate the effect of O…
View article: Antioxidant and anti-inflammatory activities of Oroxylum indicum Kurz (L.) fruit extract in lipopolysaccharide-stimulated BV2 microglial cells
Antioxidant and anti-inflammatory activities of Oroxylum indicum Kurz (L.) fruit extract in lipopolysaccharide-stimulated BV2 microglial cells Open
Purpose: To investigate the anti-inflammatory effects and antioxidant activity of Oroxylum indicum (L.) Kurz fruit extract in lipopolysaccharide (LPS)-stimulated BV2 microglia.
Methods: BV2 cells were treated with LPS for 24 h in …
View article: Oroxylum indicum (L.) extract protects human neuroblastoma SH‑SY5Y cells against β‑amyloid‑induced cell injury
Oroxylum indicum (L.) extract protects human neuroblastoma SH‑SY5Y cells against β‑amyloid‑induced cell injury Open
It has been reported that amyloid β peptide, the major component of senile plaques, serves a critical role in the development and progression of Alzheimer's disease (AD) by generating reactive oxygen species (ROS), leading to oxidative str…
View article: Valproic acid attenuates nitric oxide and interleukin‑1β production in lipopolysaccharide‑stimulated iron‑rich microglia
Valproic acid attenuates nitric oxide and interleukin‑1β production in lipopolysaccharide‑stimulated iron‑rich microglia Open
Iron accumulation in activated microglia has been consistently reported in neurodegenerative diseases. Previous results suggest that these cells facilitate neuroinflammation leading to neuronal cell death. Therefore, chemical compounds tha…
View article: Okra (<i>Abelmoschus esculentus</i> Linn) inhibits lipopolysaccharide-induced inflammatory mediators in BV2 microglial cells
Okra (<i>Abelmoschus esculentus</i> Linn) inhibits lipopolysaccharide-induced inflammatory mediators in BV2 microglial cells Open
Purpose: To investigate the inhibitory effects of okra (Abelmoschus esculentus Linn.) extract on the production of reactive oxygen species (ROS) and pro-inflammatory cytokines in lipopolysaccharide (LPS)-stimulated BV2 microglia.Methods: O…
View article: Cytotoxic and antimigratory effects of Cratoxy formosum extract against HepG2 liver cancer cells
Cytotoxic and antimigratory effects of Cratoxy formosum extract against HepG2 liver cancer cells Open
The aim of the present study was to investigate the molecular mechanisms underlying Cratoxylum formosum (CF) Dyer-induced cancer cell death and antimigratory effects in HepG2 liver cancer cells. The cytotoxic, antiproliferative and …
View article: A Variation of the Musculocutaneous and the Median Nerve Anastomosis: A Case Report in Thai Cadaver
A Variation of the Musculocutaneous and the Median Nerve Anastomosis: A Case Report in Thai Cadaver Open
This report describes a branch communicating between the musculocutaneous (MCN) and the median nerve (MN), which was detected during routine educational dissection of the right upper limb of a male cadaver in a gross anatomy class at Mahas…
View article: Double Inferior Vena Cava Co-Existing with Abdominal Aortic Aneurysm: A Case Report and Literature Review
Double Inferior Vena Cava Co-Existing with Abdominal Aortic Aneurysm: A Case Report and Literature Review Open
The embryogenesis of the inferior vena cava is a complex process involving multiple steps for the three pairs of embryonic veins. Improper completion of this process may lead to anatomic anomalies of the inferior vena cava (IVC) and its tr…