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View article: Injectable Neural Hydrogel as in vivo Therapeutic Delivery Vehicle
Injectable Neural Hydrogel as in vivo Therapeutic Delivery Vehicle Open
View article: Effects of Varied Stimulation Parameters on Adipose-Derived Stem Cell Response to Low-Level Electrical Fields
Effects of Varied Stimulation Parameters on Adipose-Derived Stem Cell Response to Low-Level Electrical Fields Open
View article: Decellularized peripheral nerve as an injectable delivery vehicle for neural applications
Decellularized peripheral nerve as an injectable delivery vehicle for neural applications Open
Damage to the nervous system can result in loss of sensory and motor function, paralysis, or even death. To facilitate neural regeneration and functional recovery, researchers have employed biomaterials strategies to address both periphera…
View article: Extracellular Matrix Disparities in an Nkx2-5 Mutant Mouse Model of Congenital Heart Disease
Extracellular Matrix Disparities in an Nkx2-5 Mutant Mouse Model of Congenital Heart Disease Open
Congenital heart disease (CHD) affects almost one percent of all live births. Despite diagnostic and surgical reparative advances, the causes and mechanisms of CHD are still primarily unknown. The extracellular matrix plays a large role in…
View article: Development of novel apoptosis-assisted lung tissue decellularization methods
Development of novel apoptosis-assisted lung tissue decellularization methods Open
Decellularized tissues hold great potential for both regenerative medicine and disease modeling applications. The acellular extracellular matrix (ECM)-enriched scaffolds can be recellularized with patient-derived cells prior to transplanta…
View article: Progress toward finding the perfect match: hydrogels for treatment of central nervous system injury
Progress toward finding the perfect match: hydrogels for treatment of central nervous system injury Open
View article: Astrocyte Mechano-Activation by High-Rate Overpressure Involves Alterations in Structural and Junctional Proteins
Astrocyte Mechano-Activation by High-Rate Overpressure Involves Alterations in Structural and Junctional Proteins Open
Primary blast neurotrauma represents a unique injury paradigm characterized by high-rate overpressure effects on brain tissue. One major hallmark of blast neurotrauma is glial reactivity, notably prolonged astrocyte activation. This cellul…
View article: Attributes of Astrocyte Response to Mechano-Stimulation by High-Rate Overpressure
Attributes of Astrocyte Response to Mechano-Stimulation by High-Rate Overpressure Open
Blast neurotrauma represents a significant mode of traumatic injury to the brain. The incidence of blast neurotrauma is particularly high amongst military combat personnel and can be debilitating and endure clinically for years after injur…
View article: A Customizable Chamber for Measuring Cell Migration
A Customizable Chamber for Measuring Cell Migration Open
Cell migration is a vital part of immune responses, growth, and wound healing. Cell migration is a complex process that involves interactions between cells, the extracellular matrix, and soluble and non-soluble chemical factors (e.g., chem…
View article: Role of Glia in Memory Deficits Following Traumatic Brain Injury: Biomarkers of Glia Dysfunction
Role of Glia in Memory Deficits Following Traumatic Brain Injury: Biomarkers of Glia Dysfunction Open
Historically, glial cells have been recognized as a structural component of the brain. However, it has become clear that glial cells are intimately involved in the complexities of neural networks and memory formations. Astrocytes, microgli…