Norbert Blank
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View article: Assessment of Health-Related Quality of Life in Patients with Active Versus Inactive Adult-Onset Still’s Disease: Data from the PRO-AOSD Survey During the COVID-19 Pandemic
Assessment of Health-Related Quality of Life in Patients with Active Versus Inactive Adult-Onset Still’s Disease: Data from the PRO-AOSD Survey During the COVID-19 Pandemic Open
Background/Objectives: To report patients’ perspectives on the impact of adult-onset Still’s disease (AOSD) on their health-related quality of life (HRQoL), work productivity and the effect of coronavirus (COVID)-19, using data from the PR…
View article: Evaluating the Divide Between Patients’ and Physicians’ Perceptions of Adult-Onset Still’s Disease Cases: Insights from the PRO-AOSD Survey
Evaluating the Divide Between Patients’ and Physicians’ Perceptions of Adult-Onset Still’s Disease Cases: Insights from the PRO-AOSD Survey Open
Background/Objectives: This study aims to report and compare data from the PRO-AOSD (patient-reported outcomes adult-onset Still’s disease) survey in patients with AOSD from the perspective of patients and their treating physicians. Method…
View article: Definition of relapse criteria in patients with rapidly progressive systemic sclerosis treated with autologous haemopoietic stem cell transplantation
Definition of relapse criteria in patients with rapidly progressive systemic sclerosis treated with autologous haemopoietic stem cell transplantation Open
View article: First-line biological versus conventional synthetic disease-modifying antirheumatic drug therapy in adult-onset Still's disease: a multicentre, retrospective, propensity weighted cohort study
First-line biological versus conventional synthetic disease-modifying antirheumatic drug therapy in adult-onset Still's disease: a multicentre, retrospective, propensity weighted cohort study Open
None.
View article: Fatal Liver Failure After Herpes‐Simplex‐Virus‐2‐Induced Acute Necrotizing Hepatitis: A Case Report
Fatal Liver Failure After Herpes‐Simplex‐Virus‐2‐Induced Acute Necrotizing Hepatitis: A Case Report Open
Herpes simplex virus (HSV) infections are common in the European population, typically presenting with mucocutaneous and anogenital manifestations. However, disseminated infections and organ involvement are rare, usually occurring in immun…
View article: Long-Term Safety and Effectiveness of Canakinumab in Patients with MKD/HIDS: Interim Analysis of the RELIANCE Registry
Long-Term Safety and Effectiveness of Canakinumab in Patients with MKD/HIDS: Interim Analysis of the RELIANCE Registry Open
Data from this interim analysis of a unique registry of patients with a rare disease support the long-term safety and effectiveness of the IL-1-blocking agent canakinumab for the treatment of MKD/HIDS.
View article: Castleman’s disease in the rheumatological practice
Castleman’s disease in the rheumatological practice Open
No abstract available.
View article: VEXAS syndrome in a male patient with fever and rash
VEXAS syndrome in a male patient with fever and rash Open
View article: Fcγ-receptor-IIIA bioactivity of circulating and synovial immune complexes in rheumatoid arthritis
Fcγ-receptor-IIIA bioactivity of circulating and synovial immune complexes in rheumatoid arthritis Open
Objective Previous technical limitations prevented the proof of Fcγ-receptor (FcγR)-activation by soluble immune complexes (sICs) in patients. FcγRIIIa (CD16) is a risk factor in rheumatoid arthritis (RA). We aimed at determining the prese…
View article: Interdisziplinäre Zentren für Autoimmunerkrankungen in Deutschland
Interdisziplinäre Zentren für Autoimmunerkrankungen in Deutschland Open
View article: Effect of ambrisentan in patients with systemic sclerosis and mild pulmonary arterial hypertension: long-term follow-up data from EDITA study
Effect of ambrisentan in patients with systemic sclerosis and mild pulmonary arterial hypertension: long-term follow-up data from EDITA study Open
View article: bDMARD can prevent the progression of AA amyloidosis to end-stage renal disease
bDMARD can prevent the progression of AA amyloidosis to end-stage renal disease Open
View article: Development and Validation of Staging Systems for AA Amyloidosis
Development and Validation of Staging Systems for AA Amyloidosis Open
Key Points Patients with AA amyloidosis and age ≥65 years, eGFR 1000 ng/L and/or type-B natriuretic peptide >130 ng/L at diagnosis have poorer survival. Proteinuria >3.0 g/24 hours and eGFR 130 ng/L and/or N -terminal type-B natriuretic pe…
View article: Clinical and serological characterization of acute pleuropericarditis suggests an autoinflammatory pathogenesis and highlights risk factors for recurrent attacks
Clinical and serological characterization of acute pleuropericarditis suggests an autoinflammatory pathogenesis and highlights risk factors for recurrent attacks Open
Purpose We describe the manifestations and course of patients with pleuropericarditis (PP). Serum parameters were analyzed to evaluate the contribution of autoimmune and autoinflammatory mechanisms to PP pathogenesis. Finally, we outline r…
View article: Long-term safety and effectiveness of canakinumab in patients with monogenic autoinflammatory diseases: results from the interim analysis of the RELIANCE registry
Long-term safety and effectiveness of canakinumab in patients with monogenic autoinflammatory diseases: results from the interim analysis of the RELIANCE registry Open
Objective Interim analysis of the RELIANCE registry, an on-going, non-interventional, open-label, multicentre, prospective study evaluating the long-term safety, dosing regimens and effectiveness of canakinumab in patients with cryopyrin-a…
View article: First-Line Biological vs. Conventional Therapy in Adult-Onset Still's Disease a Multicentre, Retrospective, Propensity Weighted Analysis
First-Line Biological vs. Conventional Therapy in Adult-Onset Still's Disease a Multicentre, Retrospective, Propensity Weighted Analysis Open
View article: Third-generation CD19.CAR-T cell-containing combination therapy in Scl70+ systemic sclerosis
Third-generation CD19.CAR-T cell-containing combination therapy in Scl70+ systemic sclerosis Open
and further staff of the Medizinische Klinik V and Thoraxklinik, Heidelberg, including
View article: Treat-to-target strategies for the management of familial Mediterranean Fever in children
Treat-to-target strategies for the management of familial Mediterranean Fever in children Open
View article: Clinical presentation and genetic variants in patients with autoinflammatory diseases: results from the German GARROD registry
Clinical presentation and genetic variants in patients with autoinflammatory diseases: results from the German GARROD registry Open
To investigate clinical symptoms and genetic variants in patients from the German anti-IL-1 registry for autoinflammatory orphan diseases (GARROD) between 2013 and 2022. Multicentre, retrospective analysis of demographic, clinical and gene…
View article: Morbus Castleman in der rheumatologischen Praxis
Morbus Castleman in der rheumatologischen Praxis Open
View article: Impact of Systemic Sclerosis-Associated Interstitial Lung Disease With and Without Pulmonary Hypertension on Survival
Impact of Systemic Sclerosis-Associated Interstitial Lung Disease With and Without Pulmonary Hypertension on Survival Open
ILD is the most prevalent pulmonary involvement in SSc, whereas the combination of ILD and PH is associated with the most detrimental survival.
View article: AB1412 THE DAMAGE OF JUVENILE IDIOPATHIC ARTHRITIS IN ADULT PATIENTS
AB1412 THE DAMAGE OF JUVENILE IDIOPATHIC ARTHRITIS IN ADULT PATIENTS Open
View article: OP0252 LONG-TERM SAFETY AND EFFECTIVENESS OF CANAKINUMAB IN CRYOPYRIN-ASSOCIATED PERIODIC SYNDROMES (CAPS) – 4-YEARS DATA FROM THE RELIANCE REGISTRY
OP0252 LONG-TERM SAFETY AND EFFECTIVENESS OF CANAKINUMAB IN CRYOPYRIN-ASSOCIATED PERIODIC SYNDROMES (CAPS) – 4-YEARS DATA FROM THE RELIANCE REGISTRY Open
View article: POS1573 LONG-TERM EFFICACY AND SAFETY OF CANAKINUMAB IN PATIENTS WITH TRAPS (TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PERIODIC SYNDROME) - INTERIM ANALYSIS OF THE RELIANCE REGISTRY
POS1573 LONG-TERM EFFICACY AND SAFETY OF CANAKINUMAB IN PATIENTS WITH TRAPS (TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PERIODIC SYNDROME) - INTERIM ANALYSIS OF THE RELIANCE REGISTRY Open
View article: AB1496 LONG-TERM EFFICACY AND SAFETY OF CANAKINUMAB IN PATIENTS WITH HIDS (HYPER-IGD SYNDROME) − INTERIM ANALYSIS OF THE RELIANCE REGISTRY
AB1496 LONG-TERM EFFICACY AND SAFETY OF CANAKINUMAB IN PATIENTS WITH HIDS (HYPER-IGD SYNDROME) − INTERIM ANALYSIS OF THE RELIANCE REGISTRY Open
View article: Characteristics and outcomes of SARS-CoV-2 breakthrough infections among double-vaccinated and triple-vaccinated patients with inflammatory rheumatic diseases
Characteristics and outcomes of SARS-CoV-2 breakthrough infections among double-vaccinated and triple-vaccinated patients with inflammatory rheumatic diseases Open
Objective To analyse the clinical profile of SARS-CoV-2 breakthrough infections in at least double-vaccinated patients with inflammatory rheumatic diseases (IRDs). Methods Data from the physician-reported German COVID-19-IRD registry colle…
View article: Hypochromic red cells as a prognostic indicator of survival among patients with systemic sclerosis screened for pulmonary hypertension
Hypochromic red cells as a prognostic indicator of survival among patients with systemic sclerosis screened for pulmonary hypertension Open
View article: Erratum to: Diagnosis and treatment of adult-onset Still’s disease: a concise summary of the German society of rheumatology S2 guideline
Erratum to: Diagnosis and treatment of adult-onset Still’s disease: a concise summary of the German society of rheumatology S2 guideline Open
View article: Oxygenated hemoglobin as prognostic marker among patients with systemic sclerosis screened for pulmonary hypertension
Oxygenated hemoglobin as prognostic marker among patients with systemic sclerosis screened for pulmonary hypertension Open
Oxygenated hemoglobin (OxyHem) in arterial blood may reflect disease severity in patients with systemic sclerosis (SSc). The aim of this study was to analyze the predictive value of OxyHem in SSc patients screened for pulmonary hypertensio…
View article: Anti-acid therapy in SSc-associated interstitial lung disease: long-term outcomes from the German Network for Systemic Sclerosis
Anti-acid therapy in SSc-associated interstitial lung disease: long-term outcomes from the German Network for Systemic Sclerosis Open
Objectives Gastroesophageal reflux disease (GERD) occurs frequently in patients with SSc. We investigated whether the presence of GERD and/or the use of anti-acid therapy, specifically proton-pump inhibitors (PPIs), are associated with lon…