Explanipedia

A pep in your strep: streptococcus pyogenes multifocal osteomyelitis and septic arthritis in an immunocompetent 7-year-old Open

D Dagdag, GH Degaffe, Norma Pérez · 2024

1625. Challenges in Addressing Congenital Syphilis in a Large Hospital System Open

Gilhen Rodriguez, Sebastian Shrager, Stacy Gomez Hernandez, Gloria P. Heresi, Asvini Thiviyanathan , et al. · 2023

Background Congenital Syphilis (CS) has increased markedly in the Houston-TX metropolitan region; the rate per 100,000 live births was 138.6 in 2018. Therefore, we reviewed CS exposures presented to our network of institutions to identify …

Durability of Cellular and Humoral Immunity After Primary and Booster Hepatitis B Vaccination of Individuals Living With Perinatally Acquired HIV Open

German Contreras, Gilhen Rodriguez, Gabriela Del Bianco, Norma Pérez, James R. Murphy , et al. · 2023

THE EDITOR-It is well known that individuals living with perinatally acquired human immunodeficiency virus (HIV) have substantial dyscrasias inside the B-cell compartment, affecting their immune response to vaccines [1-3].However, it is no…

2062. Impact of Indeterminate HIV Test Results on Efficacy of Emergency Department Routine HIV Screening Open

Elizabeth Aguilera, Gabriela Del Bianco, Gilhen Rodriguez, Norma Pérez, Gloria P. Heresi , et al. · 2022

Background In 2019, 36,801 new HIV cases were reported in the United States. Emergency Department routine HIV testing is crucial to identify new asymptomatic HIV infections. Early diagnosis followed by prompt antiretroviral therapy decreas…

Human papillomavirus vaccine effectiveness by number of doses: Updated systematic review of data from national immunization programs Open

Lauri E. Markowitz, Mélanie Drolet, Rayleen M. Lewis, Philippe Lemieux-Mellouki, Norma Pérez , et al. · 2022

Cerebral Infarctions in an Infant With COVID-19 Delta Variant Infection and Disseminated Tuberculosis Open

Stuart Fraser, Misti Ellsworth, Norma Pérez, Hunter Hamilton, Stephen A. Fletcher , et al. · 2021

926. Antibody Response to HPV Vaccination in Pediatric and Adolescent People Living with HIV (PLWH) Open

Roukaya Al Hammoud, Elizabeth R. Unger, Gitika Panicker, Gabriela Del Bianco, Gloria P. Heresi , et al. · 2020

Background Immune dysfunction related to HIV infection is associated with an inability to clear HPV infection and may compromise the immunogenicity of quadrivalent HPV vaccine Gardasil® (4v HPV). Methods Between 2005 and 2017, males and fe…

1020 Sleep and Glycemic Control in Adults With Long-Standing Type 1 Diabetes and Hypoglycemia Unawareness Open

S K Malone, Amy J. Peleckis, Allan I Pack, Norma Pérez, Yu Gao , et al. · 2020

Introduction Nocturnal hypoglycemia is life threatening for individuals with type 1 diabetes (T1D) due to loss of hypoglycemia symptom recognition (hypoglycemia unawareness) and impaired glucose counterregulation. These individuals also sh…

Health Disparities Past the Classroom: The Impact of Frontier Medicine on Students Open

Meghan White, Norma Pérez, Sema Hajmurad, Melissa Victory Brodman · 2020

Long-Term Compassionate Use of Cefiderocol To Treat Chronic Osteomyelitis Caused by Extensively Drug-Resistant Pseudomonas aeruginosa and Extended-Spectrum-β-Lactamase-Producing Klebsiella pneumoniae in a Pediatric Patient Open

Zain Alamarat, Jessica T. Babic, Truc T. Tran, Susan H. Wootton, An Q Dinh , et al. · 2019

We report a 15 year-old Nigerian adolescent male with chronic osteomyelitis caused by an extensively drug-resistant (XDR) Pseudomonas aeruginosa strain of sequence type 773 (ST773) carrying bla NDM-1 and an extended spectrum β-lactamase (E…

Teaching Medical Spanish to Improve Population Health: Evidence for Incorporating Language Education and Assessment in U.S. Medical Schools Open

Pilar Ortega, Norma Pérez, Brenda Robles, Yumirle P. Turmelle, David Acosta · 2019

Introduction: Language concordance between patients and physicians is an important factor in providing safe and effective health care, with Spanish as the predominant and fastest growing non-English language in the United Sates. How…

Medical Spanish Standardization in U.S. Medical Schools: Consensus Statement From a Multidisciplinary Expert Panel Open

Pilar Ortega, Lisa C. Diamond, Marco A. Alemán, Jaime Fatás-Cabeza, Dalia Magaña , et al. · 2019

Medical Spanish (MS) education is in growing demand from U.S. medical students, providers, and health systems, but there are no standard recommendations for how to structure the curricula, evaluate programs, or assess provider performance …

Strategies for Teaching Linguistic Preparedness for Physicians: Medical Spanish and Global Linguistic Competence in Undergraduate Medical Education Open

Pilar Ortega, Norma Pérez, Brenda Robles, Yumirle P. Turmelle, David Acosta · 2019

In accordance with Liaison Committee on Medical Education (LCME) curriculum content standards, medical schools are expected to teach physician communication skills and cultural competence. Given the sustained U.S. Spanish-speaking populati…

Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis Open

Mélanie Drolet, Élodie Bénard, Norma Pérez, Marc Brisson, Hammad Ali , et al. · 2019

TREATMENT COMPLETION AND IMPLEMENTATION BY PATIENTS INITIATING TICAGRELOR Open

Jean‐Pierre Grégoire, Paul Poirier, Norma Pérez, Éric Demers, Jocelyne Moisan · 2019

BackgroundIn secondary prevention of adverse events and death following acute coronary syndrome, patients may benefit from adhering to a ticagrelor treatment.ObjectivesThe authors assessed the proportion of new ticagrelor users who complet…

Adherence stages measured by patient-reported outcome instruments in adults with asthma: a scoping review Open

Myriam Gagné, Louis‐Philippe Boulet, Norma Pérez, Jocelyne Moisan · 2019

Objective: Individuals who are adherent to their asthma inhaled maintenance medication: (1) initiate their treatment (take the first dose); (2) implement it (take it as per prescribed dosing regimen); and persist with it (take it fo…

Review of the current published evidence on single-dose HPV vaccination 2nd Edition Open

Partha Basu, Mark Brisson, Nicole G. Campos, Ed Clarke, Mélanie Drolet , et al. · 2019

Prophylactic human papillomavirus (HPV) vaccines have been licensed for over ten years. They were initially administered as a three-dose regimen over a six-month period. In 2014, following a review of the evidence for dose reduction by the…

Adherence stages measured by patient-reported outcome instruments in adults with asthma: a scoping review Open

Myriam Gagné, Louis‐Philippe Boulet, Norma Pérez, Jocelyne Moisan · 2019

Objective: Individuals who are adherent to their asthma inhaled maintenance medication: (1) initiate their treatment (take the first dose); (2) implement it (take it as per prescribed dosing regimen); and persist with it (take it fo…

Appropriateness of Ticagrelor Use at Initiation: A Population-Based Cohort Study Open

Jean‐Pierre Grégoire, Paul Poirier, Norma Pérez, Éric Demers, Jocelyne Moisan · 2018

Purpose. Ticagrelor is recommended following an acute coronary syndrome if used appropriately. Its use has not yet been well described in the context of ambulatory clinical practice. The objective of this study was to assess the proportion…

Transverse Myelitis and Guillain-Barré Syndrome Associated with Cat-Scratch Disease, Texas, USA, 2011 Open

Ramia Zakhour, Pedro Mancías, Gloria P. Heresi, Norma Pérez · 2018

We describe a case of coexisting transverse myelitis and Guillain-Barré syndrome related to infection with Bartonella henselae proteobacterium and review similar serology-proven cases. B. henselae infection might be emerging as a cause of …

Human papillomavirus vaccine effectiveness by number of doses: Systematic review of data from national immunization programs Open

Lauri E. Markowitz, Mélanie Drolet, Norma Pérez, Mark Jit, Marc Brisson · 2018

Most post-licensure studies report highest effectiveness with three doses; some found no statistically significant difference between two and three doses. Additionally, almost half found some effectiveness with one dose. Several biases imp…

1054 Physical workload exposure threshold in cumulative-trauma disorders useful for primary prevention and for causal assessment: a 12.5 y follow-up cohort study Open

DA Alvarez-Rincón, Norma Pérez · 2018

Introduction Cumulative-Trauma Disorders (CTD) are major loss causes in labour environments through the world, but few is known about quantitative robust and reliable workload exposure limits. The aim of this research was to define shoulde…

Imported Congenital Rubella Syndrome, United States, 2017 Open

Roukaya Al Hammoud, James R. Murphy, Norma Pérez · 2018

Although transmission of rubella virus within the United States is rare, the risk for imported cases persists. We describe a rubella case in a newborn, conceived in Saudi Arabia, in Texas during 2017, highlighting the importance of active …

AB0649 Systemic sclerosis in argentina: evaluation of a single center cohort and comparison with international series Open

Mary Carrasco, LO Roa Prerez, Roy Gomez, Samira B. Leal, F M Paniego , et al. · 2017

<i>Angiostrongylus cantonensis</i> Meningitis and Myelitis, Texas, USA Open

Roukaya Al Hammoud, Stacy L. Nayes, James R. Murphy, Gloria P. Heresi, Ian J. Butler , et al. · 2017

Infection with Angiostrongylus cantonensis roundworms is endemic in Southeast Asia and the Pacific Basin. A. cantonensis meningitis and myelitis occurred in summer 2013 in a child with no history of travel outside of Texas, USA. Angiostron…

CD31 Expression on CD4+ Cells: A Simple Method for Quantitation of Recent Thymus Emigrant CD4 Cells Open

Ramia Zakhour, Dat Q. Tran, Gloria P. Heresi, Guenet H. Degaffe, Cynthia Bell , et al. · 2016

Measurements of CD4 + CD31 + cells gave results consistent with those expected for recent thymus emigrant (RTE) CD4 + cells. The method was markedly simpler than established procedures for measurement of CD4 + RTE cells and is usable in lo…

Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients Open

John S. Bradley, J. Armstrong, Antonio Arrieta, Raafat Bishai, Shampa Das , et al. · 2016

This study aimed to investigate the pharmacokinetics (PK), safety, and tolerability of a single dose of ceftazidime-avibactam in pediatric patients. A phase I, multicenter, open-label PK study was conducted in pediatric patients hospitaliz…

Recent Thymus Emigrant CD4+ T Cells Predict HIV Disease Progression in Patients With Perinatally Acquired HIV Open

Ramia Zakhour, Dat Q. Tran, Guenet H. Degaffe, Cynthia Bell, Elizabeth Donnachie , et al. · 2016

CD4+RTE% predicts disease progression and may reflect history of disease in HIV-positive patients and adolescents. They are easy to measure in the clinical setting and may be helpful markers in guiding treatment decisions.

Underweight, overweight and obesity prevalence among adolescent school children in the Province of La Pampa, Argentina Open

Fabrizio Catalani, Javier Fraire, Norma Pérez, M. Mazzola, Ana María Salinas‐Martínez , et al. · 2016

In contrast with the small prevalence of low weight in the region, overweight and obesity are a significant problem among the studied population in La Pampa.

Incidence and Predictors of Viral Suppression in a Cohort of Perinatally Human Immunodeficiency Virus-Infected Children and Adolescents Open

German Contreras, Gilhen Rodriguez, Gabriela Delbianco, Norma Pérez, James R. Murphy , et al. · 2016

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