Nour Elhouda Daoudi
YOU?
Author Swipe
View article: Harnessing the Hepatoprotective and Nephroprotective Potential of Nigella sativa Fractions via per os Administration in CCl4-Intoxicated Wistar Rats: A Mixed Approach
Harnessing the Hepatoprotective and Nephroprotective Potential of Nigella sativa Fractions via per os Administration in CCl4-Intoxicated Wistar Rats: A Mixed Approach Open
Background: Nigella sativa, known as black cumin, is traditionally used to treat various illnesses. Objective: The current study aims to investigate the potential hepatoprotective and nephroprotective effect of black cumin fractions via pe…
View article: Phytochemical Profiling, Antioxidant Capacity, and the Antidiabetic Potential of <scp> <i>Atriplex halimus</i> </scp> Extracts: <scp>UHPLC</scp> <scp>–</scp> <scp>MS</scp> <scp>/</scp> <scp>MS</scp> Analysis, In Vitro Enzyme Inhibition Assays, and Molecular Docking Studies
Phytochemical Profiling, Antioxidant Capacity, and the Antidiabetic Potential of <span> <i>Atriplex halimus</i> </span> Extracts: <span>UHPLC</span> <span>–</span> <span>MS</span> <span>/</span> <span>MS</span> Analysis, In Vitro Enzyme Inhibition Assays, and Molecular Docking Studies Open
Atriplex halimus (L.) is known to be characterized by numerous pharmacological prospects comprising antioxidant, anticancer, antibacterial, and antidiabetic properties. The core objective of the present study is to harness the chemical com…
View article: A Comparative Study of the Phytochemical Composition, Antioxidant Properties, and In Vitro Anti-Diabetic Efficacy of Different Extracts of Caulerpa prolifera
A Comparative Study of the Phytochemical Composition, Antioxidant Properties, and In Vitro Anti-Diabetic Efficacy of Different Extracts of Caulerpa prolifera Open
The Moroccan coastline has been the focus of attention for researchers studying the national algal flora, with the aim of preserving these invaluable natural resources. Since the year 2000, these resources have stimulated great interest in…
View article: Therapeutic Potential of <i>Lavandula stoechas</i> Aqueous Extract in Managing Diabetes and Its Complications: Insights From Biochemical and In Silico Studies
Therapeutic Potential of <i>Lavandula stoechas</i> Aqueous Extract in Managing Diabetes and Its Complications: Insights From Biochemical and In Silico Studies Open
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia, commonly associated with dyslipidemia, oxidative stress, and complications affecting multiple organs, including the kidneys and liver. These compl…
View article: New Generation of Hybrid Pyrazole–Tetrazole Tetrapodal Compounds: Synthesis and Biological Activities
New Generation of Hybrid Pyrazole–Tetrazole Tetrapodal Compounds: Synthesis and Biological Activities Open
The elaboration of a new family of tetrapodal molecules L1–L3 bearing two pyrazole–tetrazole units is presented. The structure assigned to such molecules was verified by various techniques, including FTIR, NMR, HRMS and elemental analysis.…
View article: Comprehensive analysis of bioactive compounds in Crocus sativus stamens extracts by HPLC-DAD: investigating antidiabetic activity via in vitro, in vivo, and molecular docking simulation
Comprehensive analysis of bioactive compounds in Crocus sativus stamens extracts by HPLC-DAD: investigating antidiabetic activity via in vitro, in vivo, and molecular docking simulation Open
Introduction: Medicinal herbs used in traditional diabetes treatment are a rich source of anti-diabetic compounds. Pancreatic α-amylase inhibitors offer an effective strategy to reduce postprandial hyperglycemic levels via control of starc…
View article: Investigation into the Phytochemical Composition, Antioxidant Properties, and In-Vitro Anti-Diabetic Efficacy of Ulva lactuca Extracts
Investigation into the Phytochemical Composition, Antioxidant Properties, and In-Vitro Anti-Diabetic Efficacy of Ulva lactuca Extracts Open
In this research, the chemical compositions of various extracts obtained from Ulva lactuca, a type of green seaweed collected from the Nador lagoon in the northern region of Morocco, were compared. Their antioxidant and anti-diabetic prope…
View article: Antioxidant, Antiglycation, Inhibition of Digestive Enzymes and Enhanced Glucose Uptake Activities of Opuntia ficus indica L, In Vitro and In Vivo
Antioxidant, Antiglycation, Inhibition of Digestive Enzymes and Enhanced Glucose Uptake Activities of Opuntia ficus indica L, In Vitro and In Vivo Open
Opuntia ficus indica L (Cactaceae), is commonly employed in Morocco as an alternative medicinal approach for managing diabetes mellitus (DM). The objective of the study is to explore and examine novel mechanism underlying the antidiabetic …
View article: Study of the Phytochemical Composition, Antioxidant Properties, and In Vitro Anti-Diabetic Efficacy of Gracilaria bursa-pastoris Extracts
Study of the Phytochemical Composition, Antioxidant Properties, and In Vitro Anti-Diabetic Efficacy of Gracilaria bursa-pastoris Extracts Open
In this study, a comparison was made of the chemical makeup of different extracts obtained from Gracilaria bursa-pastoris, a type of red seaweed that was gathered from the Nador lagoon situated in the northern part of Morocco. Additionally…
View article: In vitro α-amylase and hemoglobin glycation inhibitory potential of Nigella sativa essential oil, and molecular docking studies of its principal components
In vitro α-amylase and hemoglobin glycation inhibitory potential of Nigella sativa essential oil, and molecular docking studies of its principal components Open
Nigella sativa is plant that is endowed with various pharmacological activities including antioxidant, anticancer, anti-inflammatory, antibacterial, antidiabetic, and immunostimulant. This study aims to investigate the antidiabetic activit…
View article: Antioxidant Activity and Inhibition of Carbohydrate Digestive Enzymes Activities of Artemisia campestris L.
Antioxidant Activity and Inhibition of Carbohydrate Digestive Enzymes Activities of Artemisia campestris L. Open
Background: Carbohydrate digestive enzymes play a major role in the management of the postprandial hyperglycemia. A chronic hyperglycemia can lead to serious health problems due to excessive production of several reactive oxygen species. T…
View article: Inhibition of α-Amylase, α-Glucosidase, and Lipase, Intestinal Glucose Absorption, and Antidiabetic Properties by Extracts of Erodium guttatum
Inhibition of α-Amylase, α-Glucosidase, and Lipase, Intestinal Glucose Absorption, and Antidiabetic Properties by Extracts of Erodium guttatum Open
Erodium guttatum is widely used in traditional medicine to treat various diseases, including diabetes. In this study, we evaluated in vitro inhibitory activity of extracts of E. guttatum on α-amylase, α-glucosidase, and lipase and then stu…
View article: New pyrazole-tetrazole hybrid compounds as potent α-amylase and non-enzymatic glycation inhibitors
New pyrazole-tetrazole hybrid compounds as potent α-amylase and non-enzymatic glycation inhibitors Open
View article: Natural aldose reductase inhibitors for treatment and prevention of diabetic cataract: A review
Natural aldose reductase inhibitors for treatment and prevention of diabetic cataract: A review Open
Summary Introduction: Aldose reductase (AR) is an enzyme that catalyzes the reduction of glucose to sorbitol responsible for the development of diabetic complications like cataracts. Medicinal plants contain several phytocompounds that can…
View article: Protective effect of Crocus sativus stamens extract on gentamicin-induced nephrotoxicity and oxidative damage in rat kidney
Protective effect of Crocus sativus stamens extract on gentamicin-induced nephrotoxicity and oxidative damage in rat kidney Open
Crocus sativus is a medicinal plant supposedly possessing various biological activities. Currently, it is evaluated only by the medicinal properties of its stigma and many parts of this plant are unused. This work contributes to the valori…
View article: Artemisia absinthium L. Aqueous and Ethyl Acetate Extracts: Antioxidant Effect and Potential Activity In Vitro and In Vivo against Pancreatic α-Amylase and Intestinal α-Glucosidase
Artemisia absinthium L. Aqueous and Ethyl Acetate Extracts: Antioxidant Effect and Potential Activity In Vitro and In Vivo against Pancreatic α-Amylase and Intestinal α-Glucosidase Open
Artemisia absinthium L. is one of the plants which has been used in folk medicine for many diseases over many centuries. This study aims to analyze the chemical composition of the Artemisia absinthium ethyl acetate and its aqueous extracts…
View article: Ammodaucus leucotrichus Coss. & Durieu: Antihyperglycemic activity via the inhibition of α-amylase, α-glucosidase, and intestinal glucose absorption activities and its chemical composition
Ammodaucus leucotrichus Coss. & Durieu: Antihyperglycemic activity via the inhibition of α-amylase, α-glucosidase, and intestinal glucose absorption activities and its chemical composition Open
Context: Ammodaucus leucotrichus commonly known as a ‘Kamune es sufi or akâman’ in Morocco, is used to treat many diseases including diabetes. Aims: To investigate the antihyperglycemic activity of an aqueous extract of fruits A. leucotric…
View article: Protective Effect of Opuntia dillenii (Ker Gawl.) Haw. Seed Oil on Gentamicin-Induced Nephrotoxicity: A Biochemical and Histological Analysis
Protective Effect of Opuntia dillenii (Ker Gawl.) Haw. Seed Oil on Gentamicin-Induced Nephrotoxicity: A Biochemical and Histological Analysis Open
Opuntia dillenii is a medicinal plant with frequent usage in folk medicine to treat many illnesses. The present study aims to investigate the protective effect of Opuntia dillenii seed oil against gentamicin-induced nephrotoxicity in rats.…
View article: Phytochemistry and biological activities of <i>Opuntia</i> seed oils: <i>Opuntia dillenii</i> (Ker Gawl.) Haw. and <i>Opuntia ficus-indica</i> (L.) Mill. A review
Phytochemistry and biological activities of <i>Opuntia</i> seed oils: <i>Opuntia dillenii</i> (Ker Gawl.) Haw. and <i>Opuntia ficus-indica</i> (L.) Mill. A review Open
Summary Opuntia species belong to semi-arid and arid regions of Mexico and the United States. O. ficus-indica and O. dillenii are commonly used in alternative medicine to treat various diseases. Up to date, several scientific works have be…
View article: Opuntia dillenii (Ker Gawl.) Haw., Seeds Oil Antidiabetic Potential Using In Vivo, In Vitro, In Situ, and Ex Vivo Approaches to Reveal Its Underlying Mechanism of Action
Opuntia dillenii (Ker Gawl.) Haw., Seeds Oil Antidiabetic Potential Using In Vivo, In Vitro, In Situ, and Ex Vivo Approaches to Reveal Its Underlying Mechanism of Action Open
Opuntia dillenii Ker Gawl. is one of the medicinal plants used for the prevention and treatment of diabetes mellitus (DM) in Morocco. This study aims to investigate the antihyperglycemic effect of Opuntia dillenii seed oil (ODSO), its mech…
View article: Evaluation of Hepatoprotective Activity of Caralluma europaea Stem Extract against CCl4-Induced Hepatic Damage in Wistar Rats
Evaluation of Hepatoprotective Activity of Caralluma europaea Stem Extract against CCl4-Induced Hepatic Damage in Wistar Rats Open
The present study aims to evaluate the hepatoprotective activity of stem aqueous extract of Caralluma europaea (AECe) on carbon tetrachloride- (CCl4-) induced hepatic damage in Wistar rats. The animals were daily treated with the aqueous e…
View article: Chemical Composition Analysis Using HPLC‐UV/GC‐MS and Inhibitory Activity of Different <i>Nigella sativa</i> Fractions on Pancreatic <i>α</i>‐Amylase and Intestinal Glucose Absorption
Chemical Composition Analysis Using HPLC‐UV/GC‐MS and Inhibitory Activity of Different <i>Nigella sativa</i> Fractions on Pancreatic <i>α</i>‐Amylase and Intestinal Glucose Absorption Open
Nigella sativa (NS) is a well‐known plant for its various benefits and multiuse in traditional medicine. This study is aimed at investigating the chemical composition of the different NS fractions by using GC‐MS for the esterified fatty ac…
View article: Medicinal Plants as a Drug Alternative Source for the Antigout Therapy in Morocco
Medicinal Plants as a Drug Alternative Source for the Antigout Therapy in Morocco Open
Background. The gout is a metabolic disease that is associated with a high level of uric acid in the blood. This disease is treated with some medications that aim to reduce serum urate levels. However, the use of various medicines leads to…
View article: Inhibitory effect of roasted/ unroasted Argania spinosa seeds oil on α- glucosidase, α-amylase and intestinal glucose absorption activities
Inhibitory effect of roasted/ unroasted Argania spinosa seeds oil on α- glucosidase, α-amylase and intestinal glucose absorption activities Open
Diabetes mellitus is a serious metabolic disease, which affects a large number of populations in the world. Phytotherapy is considered as the most remedies used by Moroccan people to treat this pathology. Argania spinosa L. (SKEELS) seeds …
View article: Hepatoprotective Essential Oils: A Review
Hepatoprotective Essential Oils: A Review Open
In this work, we classified the plants; contain the essential oils, in alphabetical order as a table containing the scientific, family names, information plants, the experimental assay and the results obtained from the hepatoprotective stu…
View article: Phenolic Content and Antioxidant, Antihyperlipidemic, and Antidiabetogenic Effects of Opuntia dillenii Seed Oil
Phenolic Content and Antioxidant, Antihyperlipidemic, and Antidiabetogenic Effects of Opuntia dillenii Seed Oil Open
Opuntia dillenii (Ker-Gawl.) Haw. is a medicinal plant that is widely used by the Moroccan population to treat many diseases, thanks to its richness in bioactive molecules. This study aims to evaluate the total phenolic content and antioxi…
View article: The Pathogenesis of Coronavirus Disease 2019 (COVID‐19): Evaluation and Prevention
The Pathogenesis of Coronavirus Disease 2019 (COVID‐19): Evaluation and Prevention Open
Coronavirus Disease 2019 (COVID‐19) has become a major health problem causing severe acute respiratory illness in humans. It has spread rapidly around the globe since its first identification in Wuhan, China, in December 2019. The causativ…