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View article: Bacteriophage-enhanced doxycycline activity against Escherichia coli in chronic bacterial prostatitis
Bacteriophage-enhanced doxycycline activity against Escherichia coli in chronic bacterial prostatitis Open
Although the E. coli strain was resistant to doxycycline, the antibiotic was administered specifically to target the Mycoplasma infection. Interestingly, the enhanced in vitro activity observed when the antibiotic was combined with phages …
View article: Human serum lipids affect Staphylococcus aureus sensitivity to phage infection
Human serum lipids affect Staphylococcus aureus sensitivity to phage infection Open
Taken together, our findings suggest that serum lipid fraction impacts phage infectivity in a strain-specific manner, highlighting the need for tailored approaches for phage therapy.
View article: P23. Development of phage therapy in Italy for the treatment of difficult-to-treat bacterial infections
P23. Development of phage therapy in Italy for the treatment of difficult-to-treat bacterial infections Open
Background Difficult-to-treat bacterial infections represent a significant public health issue.1 Phage therapy is emerging as a promising strategy to be combined with antibiotic treatment for their eradication.2 In Italy, the demand for th…
View article: Characterisation of four novel bacteriophages targeting carbapenem-resistant Klebsiella pneumoniae and their lytic activity alone and in combination
Characterisation of four novel bacteriophages targeting carbapenem-resistant Klebsiella pneumoniae and their lytic activity alone and in combination Open
Klebsiella pneumoniae is a nosocomial pathogen with rising levels of antibiotic resistance, increasing interest in bacteriophage therapy as an adjunct or alternative treatment. This study aimed to isolate and characterise bacteriophages ac…
View article: Management of an elderly patient with retention of a steel nail in the scrotum: a case report
Management of an elderly patient with retention of a steel nail in the scrotum: a case report Open
Background: The retention of foreign bodies inside the body during ludic/sexual procedures or for traumatism represents one of the causes of visits to accident and emergency departments that often requires surgical removal of the foreign b…
View article: Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study
Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study Open
View article: Evaluation of antibiofilm activity of cefiderocol alone and in combination with imipenem against Pseudomonas aeruginosa
Evaluation of antibiofilm activity of cefiderocol alone and in combination with imipenem against Pseudomonas aeruginosa Open
Cefiderocol exhibited an encouraging antibiofilm activity against tested strains, representing a valid option for the treatment of P. aeruginosa biofilm-associated infections, especially when administered in combination with imipenem.
View article: Efficacy of Convalescent Plasma to Treat Long-Standing COVID-19 in Patients with B-Cell Depletion
Efficacy of Convalescent Plasma to Treat Long-Standing COVID-19 in Patients with B-Cell Depletion Open
The use of antivirals, corticosteroids, and IL-6 inhibitors has been recommended by the WHO to treat COVID-19. CP has also been considered for severe and critical cases. Clinical trials on CP have shown contradictory results, but an increa…
View article: Application of Phage Therapy in a Case of a Chronic Hip-Prosthetic Joint Infection due to<i>Pseudomonas aeruginosa</i>: An Italian Real-Life Experience and<i>In Vitro</i>Analysis
Application of Phage Therapy in a Case of a Chronic Hip-Prosthetic Joint Infection due to<i>Pseudomonas aeruginosa</i>: An Italian Real-Life Experience and<i>In Vitro</i>Analysis Open
Background Prosthetic joint infection (PJI) caused by Pseudomonas aeruginosa represents a severe complication in orthopedic surgery. We report the case of a patient with chronic PJI from P. aeruginosa successfully treated with personalized…
View article: Phage-Based Control of Methicillin Resistant Staphylococcus aureus in a Galleria mellonella Model of Implant-Associated Infection
Phage-Based Control of Methicillin Resistant Staphylococcus aureus in a Galleria mellonella Model of Implant-Associated Infection Open
Staphylococcus aureus implant-associated infections are difficult to treat because of the ability of bacteria to form biofilm on medical devices. Here, the efficacy of Sb-1 to control or prevent S. aureus colonization on medical foreign bo…
View article: Depressive and anxiety symptoms in patients with SARS-CoV2 infection
Depressive and anxiety symptoms in patients with SARS-CoV2 infection Open
View article: Mild clinical manifestations of SARS-CoV-2 related pneumonia in two patients with multiple sclerosis under treatment with ocrelizumab
Mild clinical manifestations of SARS-CoV-2 related pneumonia in two patients with multiple sclerosis under treatment with ocrelizumab Open
View article: Sleep and wake impairment in patients with SARS-CoV2 infection
Sleep and wake impairment in patients with SARS-CoV2 infection Open
View article: Subjective neurological symptoms frequently occur in patients with SARS-CoV2 infection
Subjective neurological symptoms frequently occur in patients with SARS-CoV2 infection Open
View article: HBcAb seropositivity is correlated with poor HIV viremia control in an Italian cohort of HIV/HBV-coinfected patients on first-line therapy
HBcAb seropositivity is correlated with poor HIV viremia control in an Italian cohort of HIV/HBV-coinfected patients on first-line therapy Open