Nuno R. Faria
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View article: Scientific Update on The Treatment of Rheumatoid Arthritis: A Systematic Review with Meta-Analysis
Scientific Update on The Treatment of Rheumatoid Arthritis: A Systematic Review with Meta-Analysis Open
Objective: To update the treatment and management of rheumatoid arthritis. The secondary objective is to provide the orthopedic medical community with greater confidence in evidence-based treatment. Methodology: Systematic review with meta…
View article: Fast and Trustworthy Nowcasting of Dengue Fever: A Case Study Using Attention-Based Probabilistic Neural Networks in São Paulo, Brazil
Fast and Trustworthy Nowcasting of Dengue Fever: A Case Study Using Attention-Based Probabilistic Neural Networks in São Paulo, Brazil Open
Nowcasting methods are crucial in infectious disease surveillance, as reporting delays often lead to underestimation of recent incidence and can impair timely public health decision-making. Accurate real-time estimates of case counts are e…
View article: Case report: Dengue virus serotype 3 and Oropouche virus co-infection in a Cuban traveller diagnosed in Portugal, November 2024
Case report: Dengue virus serotype 3 and Oropouche virus co-infection in a Cuban traveller diagnosed in Portugal, November 2024 Open
In 2024, unprecedented outbreaks of dengue virus (DENV) and Oropouche virus (OROV) were reported in Latin America and the Caribbean. We describe a case of co-infection with DENV serotype 3 and OROV imported into Portugal from Cuba. RT-PCR …
View article: The overlapping global distribution of dengue, chikungunya, Zika and yellow fever
The overlapping global distribution of dengue, chikungunya, Zika and yellow fever Open
Arboviruses transmitted mainly by Aedes ( Stegomyia ) aegypti and Ae. albopictus , including dengue, chikungunya, and Zika viruses, and yellow fever virus in urban settings, pose an escalating global threat. Existing risk maps, often hampe…
View article: Yellow fever virus resurgence in São Paulo State, Brazil, 2024-2025
Yellow fever virus resurgence in São Paulo State, Brazil, 2024-2025 Open
Yellow fever virus (YFV) was detected in two distinct geographic locations in São Paulo State, Brazil, between September 2024 and February 2025. Phylogenetic analysis of six new genomes revealed a re-introduction in 2022 from Midwest Brazi…
View article: Proactive One-Health surveillance reveals novel orthobunyaviruses and their potential vectors and reservoirs
Proactive One-Health surveillance reveals novel orthobunyaviruses and their potential vectors and reservoirs Open
Mosquito-borne viruses pose a significant, global threat to human and animal health. Traditionally, arthropod-borne virus (arbovirus) surveillance has been retroactive following an outbreak, which limits the ability to predict and prevent …
View article: Dengue Transmission Dynamics and Spread in Angola: A Phylogenetic and Cross-Sectional Seroprevalence Study
Dengue Transmission Dynamics and Spread in Angola: A Phylogenetic and Cross-Sectional Seroprevalence Study Open
View article: Re-emergence of Oropouche virus between 2023 and 2024 in Brazil: an observational epidemiological study
Re-emergence of Oropouche virus between 2023 and 2024 in Brazil: an observational epidemiological study Open
For the Portuguese translation of the abstract see Supplementary Materials section.
View article: A new lineage nomenclature to aid genomic surveillance of dengue virus
A new lineage nomenclature to aid genomic surveillance of dengue virus Open
Dengue virus (DENV) is currently causing epidemics of unprecedented scope in endemic settings and expanding to new geographical areas. It is therefore critical to track this virus using genomic surveillance. However, the complex patterns o…
View article: The overlapping global distribution of dengue, chikungunya, Zika and yellow fever
The overlapping global distribution of dengue, chikungunya, Zika and yellow fever Open
Arboviruses transmitted mainly by Aedes (Stegomiya) aegypti and Ae. albopictus in urban settings, including dengue, chikungunya, Zika, and yellow fever viruses, pose an escalating global threat. Existing risk maps, often hampered by survei…
View article: Reemergence of Oropouche virus between 2023 and 2024 in Brazil
Reemergence of Oropouche virus between 2023 and 2024 in Brazil Open
Background Oropouche virus (OROV; species Orthobunyavirus oropoucheense ) is an arthropod-borne virus that has caused outbreaks of Oropouche fever in Central and South America since the 1950s. This study investigates virological factors co…
View article: The Looming Threat of Dengue Fever: The Africa Context
The Looming Threat of Dengue Fever: The Africa Context Open
In Africa, compared to 2019, dengue infections have surged ninefold by December 2023, with over 270 000 cases and 753 deaths reported across 18 African Union (AU) Member States. This commentary synthesises the context of dengue outbreaks i…
View article: Human movement and environmental barriers shape the emergence of dengue
Human movement and environmental barriers shape the emergence of dengue Open
View article: A new lineage nomenclature to aid genomic surveillance of dengue virus
A new lineage nomenclature to aid genomic surveillance of dengue virus Open
Dengue virus (DENV) is currently causing epidemics of unprecedented scope in endemic settings and expanding to new geographical areas. It is therefore critical to track this virus using genomic surveillance. However, the complex patterns o…
View article: Molecular Epidemiology of Mayaro Virus among Febrile Patients, Roraima State, Brazil, 2018–2021
Molecular Epidemiology of Mayaro Virus among Febrile Patients, Roraima State, Brazil, 2018–2021 Open
We detected Mayaro virus (MAYV) in 3.4% (28/822) of febrile patients tested during 2018-2021 from Roraima State, Brazil. We also isolated MAYV strains and confirmed that these cases were caused by genotype D. Improved surveillance is neede…
View article: Pathophysiology of chikungunya virus infection associated with fatal outcomes
Pathophysiology of chikungunya virus infection associated with fatal outcomes Open
View article: Mpox continues to spread in Africa and threatens global health security
Mpox continues to spread in Africa and threatens global health security Open
View article: Clinical and epidemiological characteristics of Madariaga and Venezuelan equine encephalitis virus infections
Clinical and epidemiological characteristics of Madariaga and Venezuelan equine encephalitis virus infections Open
Madariaga virus (MADV) and Venezuelan equine encephalitis virus (VEEV) are emerging arboviruses affecting rural and remote areas of Latin America. However, there are limited clinical and epidemiological reports available, and outbreaks are…
View article: Tracking arboviruses, their transmission vectors and potential hosts by nanopore sequencing of mosquitoes
Tracking arboviruses, their transmission vectors and potential hosts by nanopore sequencing of mosquitoes Open
The risk to human health from mosquito-borne viruses such as dengue, chikungunya and yellow fever is increasing due to increased human expansion, deforestation and climate change. To anticipate and predict the spread and transmission of mo…
View article: Characteristics of Madariaga and Venezuelan Equine Encephalitis Virus Infections, Panama
Characteristics of Madariaga and Venezuelan Equine Encephalitis Virus Infections, Panama Open
Madariaga virus (MADV) and Venezuelan equine encephalitis virus (VEEV) are emerging arboviruses affecting rural and remote areas of Latin America. However, clinical and epidemiologic reports are limited, and outbreaks are occurring at an i…
View article: SARS-CoV-2 shedding, infectivity, and evolution in an immunocompromised adult patient
SARS-CoV-2 shedding, infectivity, and evolution in an immunocompromised adult patient Open
This study aimed to provide further insight into the evolutionary dynamics of SARS-CoV-2 by analyzing the case of a 40-year-old man who had previously undergone autologous hematopoietic stem cell transplantation due to a diffuse large B-ce…
View article: Characteristics of Madariaga and Venezuelan Equine Encephalitis Virus Infections, Panama
Characteristics of Madariaga and Venezuelan Equine Encephalitis Virus Infections, Panama Open
View article: A one-step low-cost molecular test for SARS-CoV-2 detection suitable for community testing using minimally processed saliva
A one-step low-cost molecular test for SARS-CoV-2 detection suitable for community testing using minimally processed saliva Open
The gold standard for coronavirus disease 2019 diagnostic testing relies on RNA extraction from naso/oropharyngeal swab followed by amplification through reverse transcription-polymerase chain reaction (RT-PCR) with fluorogenic probes. Whi…
View article: Mental Health, the COVID-19 Pandemic and Social Inequalities: An Integrative Review
Mental Health, the COVID-19 Pandemic and Social Inequalities: An Integrative Review Open
View article: Lessons from a Multilaboratorial Task Force for Diagnosis of a Fatal Toxoplasmosis Outbreak in Captive Primates in Brazil
Lessons from a Multilaboratorial Task Force for Diagnosis of a Fatal Toxoplasmosis Outbreak in Captive Primates in Brazil Open
Toxoplasmosis is an important zoonotic disease caused by the parasite Toxoplasma gondii and is especially fatal for neotropical primates. In Brazil, the Ministry of Health is responsible for national epizootic surveillance, but some diseas…
View article: Real-time RT-PCR for Venezuelan equine encephalitis complex, Madariaga, and Eastern equine encephalitis viruses: application in human and mosquito public health surveillance in Panama
Real-time RT-PCR for Venezuelan equine encephalitis complex, Madariaga, and Eastern equine encephalitis viruses: application in human and mosquito public health surveillance in Panama Open
Eastern equine encephalitis virus (EEEV), Madariaga virus (MADV), and Venezuelan equine encephalitis virus complex (VEEV) are New World alphaviruses transmitted by mosquitoes. They cause febrile and sometimes severe neurological diseases i…
View article: SARS-CoV-2 lineage-specific disease symptoms and disease severity in São Caetano do Sul city, Brazil
SARS-CoV-2 lineage-specific disease symptoms and disease severity in São Caetano do Sul city, Brazil Open
Background The city of São Caetano do Sul, Brazil, established a web-based platform to provide primary care to suspected COVID-19 patients, integrating clinical and demographic data and sample metadata. Here we describe lineage-specific sp…
View article: Epidemiological and genomic investigation of chikungunya virus in Rio de Janeiro state, Brazil, between 2015 and 2018
Epidemiological and genomic investigation of chikungunya virus in Rio de Janeiro state, Brazil, between 2015 and 2018 Open
Since 2014, Brazil has experienced an unprecedented epidemic caused by chikungunya virus (CHIKV), with several waves of East-Central-South-African (ECSA) lineage transmission reported across the country. In 2018, Rio de Janeiro state, the …
View article: Lessons from a multilaboratorial task force for diagnosis of a fatal toxoplasmosis outbreak in captive primates in Brazil
Lessons from a multilaboratorial task force for diagnosis of a fatal toxoplasmosis outbreak in captive primates in Brazil Open
As exemplified by the Coronavirus Disease 2019 (COVID-19) pandemic, infectious diseases may emerge and spread rapidly, often causing serious economic losses and public health concerns. In fact, disease outbreaks have become increasingly co…
View article: Correction: Implementation of Genomic Surveillance of SARS-CoV-2 in the Caribbean: Lessons learned for sustainability in resource-limited settings
Correction: Implementation of Genomic Surveillance of SARS-CoV-2 in the Caribbean: Lessons learned for sustainability in resource-limited settings Open
[This corrects the article DOI: 10.1371/journal.pgph.0001455.].