Nur Aishah Mohd Taib
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View article: Threshold-Based Overlap of Breast Cancer High-Risk Classification Using Family History, Polygenic Risk Scores, and Traditional Risk Models in 180,398 Women
Threshold-Based Overlap of Breast Cancer High-Risk Classification Using Family History, Polygenic Risk Scores, and Traditional Risk Models in 180,398 Women Open
Background: Breast cancer polygenic risk scores (PRS) and traditional risk models (e.g., the Gail model [Gail]) are known to contribute largely independent information, but it is unclear how the overlap varies by ancestry, age, disease typ…
View article: Polygenic risk score for breast cancer risk prediction in Asian BRCA1 and BRCA2 pathogenic variants carriers
Polygenic risk score for breast cancer risk prediction in Asian BRCA1 and BRCA2 pathogenic variants carriers Open
Polygenic risk scores (PRS) have been shown to be predictive of breast cancer (BC) risk in European BRCA1 and BRCA2 pathogenic variant (PV) carriers, but their utility in Asian populations has not been evaluated. In this study, we evaluate…
View article: MyGESig: a population-specific gene signature improves survival prediction in Malaysian breast cancer patients
MyGESig: a population-specific gene signature improves survival prediction in Malaysian breast cancer patients Open
Accurate prognostic models are essential for guiding treatment decisions and improving patient outcomes in breast cancer. To achieve this, population-specific models are needed to account for genetic, clinical, and pathological differences…
View article: CLICK, MEASURE, SUCCEED: A BIBLIOMETRIC JOURNEY AND EMERGING RESEARCH GAPS IN INFORMATION SYSTEMS (IS) EFFECTIVENESS
CLICK, MEASURE, SUCCEED: A BIBLIOMETRIC JOURNEY AND EMERGING RESEARCH GAPS IN INFORMATION SYSTEMS (IS) EFFECTIVENESS Open
Information Systems (IS) effectiveness has emerged as a critical research area in the face of rapid digital transformation and the increasing reliance on technology across various sectors. Despite the field’s maturity, theoretical developm…
View article: Part II: consensus statements and expert recommendations for BRCA-associated breast cancer in the Asia-Pacific region: clinical management
Part II: consensus statements and expert recommendations for BRCA-associated breast cancer in the Asia-Pacific region: clinical management Open
Introduction Existing guidelines have practical gaps in decision and treatment sequencing for BRCA germline pathogenic variant breast cancers. This paper aims to develop clinical-practice consensus guidelines to address these gaps in the c…
View article: Part I: consensus statements and expert recommendations for HER2-negative early breast cancer in the Asia-Pacific region: diagnosis and risk assessment
Part I: consensus statements and expert recommendations for HER2-negative early breast cancer in the Asia-Pacific region: diagnosis and risk assessment Open
Introduction In the Asia-Pacific region, there is increasing contention on the practical challenges involved in managing human epidermal growth factor receptor 2 (HER2)-negative early breast cancer (eBC). This modified Delphi consensus exp…
View article: BRIDGING TECHNOLOGY AND QUALITY: A SYSTEMATIC REVIEW OF INFORMATION SYSTEM (IS) EFFECTIVENESS IN ENHANCING TAX AUDIT QUALITY
BRIDGING TECHNOLOGY AND QUALITY: A SYSTEMATIC REVIEW OF INFORMATION SYSTEM (IS) EFFECTIVENESS IN ENHANCING TAX AUDIT QUALITY Open
In an era of accelerating digital transformation, the integrity and efficiency of tax audits have become more critical than ever. As governments confront increasing fiscal pressures, ensuring high-quality audits is essential to safeguardin…
View article: Efficacy and safety of Lignosus rhinocerus (Cooke) Ryvarden TM02® supplementation for immune-challenged patients with localised breast cancer in remission: a randomised controlled trial
Efficacy and safety of Lignosus rhinocerus (Cooke) Ryvarden TM02® supplementation for immune-challenged patients with localised breast cancer in remission: a randomised controlled trial Open
Our study found that TM02®, a natural supplement containing standardized compounds from Lignosus rhinocerus, is well tolerated in patients with localized breast cancer post-adjuvant chemotherapy. TM02® supplementation…
View article: IoT-Integrated Smart Gardening System for Real-Time Monitoring and User-Controlled with Smart Film
IoT-Integrated Smart Gardening System for Real-Time Monitoring and User-Controlled with Smart Film Open
Internet of things (IoT) refers to devices connected to the internet that enable human-to-human or human-to-computer communication. It facilitates the collection and exchange of data between these devices and users. This study presents an …
View article: Overlap of high-risk individuals across family history, genetic & non-genetic breast cancer risk models: Analysis of 180,398 women from European & Asian ancestries
Overlap of high-risk individuals across family history, genetic & non-genetic breast cancer risk models: Analysis of 180,398 women from European & Asian ancestries Open
Background Breast cancer is multifactorial. Focusing on limited risk factors may miss high-risk individuals. Methods We assessed the performance and overlap of various risk factors in identifying high-risk individuals for invasive breast c…
View article: Overlap of High-Risk Individuals Predicted by Family History, Genetic and Non-Genetic Breast Cancer Risk Prediction Models: An Analysis of 180,398 Women Across European and Asian Ancestry Populations
Overlap of High-Risk Individuals Predicted by Family History, Genetic and Non-Genetic Breast Cancer Risk Prediction Models: An Analysis of 180,398 Women Across European and Asian Ancestry Populations Open
View article: Framework-Guided Development and Testing of a Culturally Sensitive Decision Aid for Multiethnic Brca Pathogenic Variant Carriers in Malaysia Considering Risk-Reducing Salpingo-Oophorectomy
Framework-Guided Development and Testing of a Culturally Sensitive Decision Aid for Multiethnic Brca Pathogenic Variant Carriers in Malaysia Considering Risk-Reducing Salpingo-Oophorectomy Open
View article: A CRITICAL REVIEW OF TAX AUDIT QUALITY FACTORS: A RESEARCH SYNTHESIS
A CRITICAL REVIEW OF TAX AUDIT QUALITY FACTORS: A RESEARCH SYNTHESIS Open
The quality of tax audits plays a critical role in ensuring the transparency, accuracy, and integrity of the taxation system, which in turn contributes to public confidence and higher tax compliance. In an increasingly complex and dynamic …
View article: Proteomic Profiling of Serum of Women with Bi-Rads 1 to 5: Identification of Potential Complementary Biomarkers for Early Detection of Breast Cancer
Proteomic Profiling of Serum of Women with Bi-Rads 1 to 5: Identification of Potential Complementary Biomarkers for Early Detection of Breast Cancer Open
Mammography remains the gold standard for the screening of breast cancer (BrCa) despite its shortcomings. Cancer antigen 15-3, an FDA-approved biomarker, is most useful as a treatment response and recurrence monitoring tool rather than for…
View article: Trends in Presentation, Management, and Survival of Women With Breast Cancer in a Multiethnic, Middle-Income Asian Setting
Trends in Presentation, Management, and Survival of Women With Breast Cancer in a Multiethnic, Middle-Income Asian Setting Open
PURPOSE Granular data on breast cancer (BC) are pertinent for surveillance, planning, and monitoring of cancer care delivery. We determined the trends in clinical presentation, management, and survival of women with BC in a multiethnic mid…
View article: Gene expression signature for predicting homologous recombination deficiency in triple-negative breast cancer
Gene expression signature for predicting homologous recombination deficiency in triple-negative breast cancer Open
Triple-negative breast cancers (TNBCs) are a subset of breast cancers that have remained difficult to treat. A proportion of TNBCs arising in non-carriers of BRCA pathogenic variants have genomic features that are similar to BRCA carriers …
View article: Non Adherence to Post Surgery Annual Surveilance Mammogram and Follow Up Among Breast Cancer Survivors in a Tertiary Care Hospital in Malaysia
Non Adherence to Post Surgery Annual Surveilance Mammogram and Follow Up Among Breast Cancer Survivors in a Tertiary Care Hospital in Malaysia Open
PURPOSE The importance of surveillance mammogram and follow up post breast cancer surgery has been emphasised in most international and local guidelines including Malaysian Clinical Practice Guidelines (CPG). There is insufficient real-wor…
View article: Association of area- and volumetric-mammographic density and breast cancer risk in women of Asian descent: a case control study
Association of area- and volumetric-mammographic density and breast cancer risk in women of Asian descent: a case control study Open
View article: Clustering of HR + /HER2− breast cancer in an Asian cohort is driven by immune phenotypes
Clustering of HR + /HER2− breast cancer in an Asian cohort is driven by immune phenotypes Open
Breast cancer exhibits significant heterogeneity, manifesting in various subtypes that are critical in guiding treatment decisions. This study aimed to investigate the existence of distinct subtypes of breast cancer within the Asian popula…
View article: Age-specific breast and ovarian cancer risks associated with germline BRCA1 or BRCA2 pathogenic variants – an Asian study of 572 families
Age-specific breast and ovarian cancer risks associated with germline BRCA1 or BRCA2 pathogenic variants – an Asian study of 572 families Open
View article: JURNI (Journeying with Patients’ Understanding and Responding to Needs Interactively): An In-Hospital Navigation Application for Timely Diagnosis and Treatment of Breast Cancer at the University Malaya Medical Centre
JURNI (Journeying with Patients’ Understanding and Responding to Needs Interactively): An In-Hospital Navigation Application for Timely Diagnosis and Treatment of Breast Cancer at the University Malaya Medical Centre Open
One of the main challenges in breast cancer management is health system literacy to provide optimal and timely diagnosis and treatments within complex and multidisciplinary health system environments. Digitalised patient navigation program…
View article: Clustering of HR+/HER2- breast cancer in an Asian cohort is driven by immune phenotypes
Clustering of HR+/HER2- breast cancer in an Asian cohort is driven by immune phenotypes Open
Breast cancer exhibits significant heterogeneity, manifesting in various subtypes that are critical in guiding treatment decisions. This study aimed to investigate the existence of distinct subtypes of breast cancer within the Asian popula…
View article: Breast conserving surgery versus mastectomy: the effect of surgery on quality of life in breast cancer survivors in Malaysia
Breast conserving surgery versus mastectomy: the effect of surgery on quality of life in breast cancer survivors in Malaysia Open
View article: The development and evaluation of a mHealth, community education and navigation intervention to improve clinical breast examination uptake in Segamat Malaysia: A randomised controlled trial
The development and evaluation of a mHealth, community education and navigation intervention to improve clinical breast examination uptake in Segamat Malaysia: A randomised controlled trial Open
Introduction Breast cancer (BC) screening uptake in Malaysia is low and a high number of cases present at a late stage. Community navigation and mobile health (mHealth) may increase screening attendance, particularly by women from rural co…
View article: The “Know Your Lemons” Tools: A strategy to improve breast cancer warning signs recognition in Malaysia
The “Know Your Lemons” Tools: A strategy to improve breast cancer warning signs recognition in Malaysia Open
BACKGROUND: Breast cancer (BC) is the most common cancer in Malaysia, with many diagnosed at late stages. The “Know Your Lemons” (KYL) visual educational tools were developed by KYL Foundation. This study aimed to evaluate participants' co…
View article: Natural language processing in narrative breast radiology reporting in University Malaya Medical Centre
Natural language processing in narrative breast radiology reporting in University Malaya Medical Centre Open
Radiology reporting is narrative, and its content depends on the clinician’s ability to interpret the images accurately. A tertiary hospital, such as anonymous institute, focuses on writing reports narratively as part of training for medic…
View article: Evaluation of SNPs associated with mammographic density in European women with mammographic density in Asian women from South-East Asia
Evaluation of SNPs associated with mammographic density in European women with mammographic density in Asian women from South-East Asia Open
View article: Association between pre-existing cardiometabolic comorbidities and the pathological profiles of breast cancer at initial diagnosis: a cross sectional study
Association between pre-existing cardiometabolic comorbidities and the pathological profiles of breast cancer at initial diagnosis: a cross sectional study Open
The presence of comorbidities has been associated with later stages of breast cancer diagnosis.It is unclear whether biological mechanisms are partly responsible.We examined the association between the presence of pre-existing comorbiditie…
View article: Discriminatory Ability and Clinical Utility of the AJCC7 and AJCC8 Staging Systems for Breast Cancer in a Middle-Income Setting
Discriminatory Ability and Clinical Utility of the AJCC7 and AJCC8 Staging Systems for Breast Cancer in a Middle-Income Setting Open
(1) Background: Differences in access to biomarker testing and cancer treatment in resource-limited settings may affect the clinical utility of the AJCC8 staging system compared to the anatomical AJCC7 system. (2) Methods: A total of 4151 …
View article: Development and Validation of a Dual-Language (English and Malay) Needs Assessment Tool for Breast Cancer (NeAT-BC)
Development and Validation of a Dual-Language (English and Malay) Needs Assessment Tool for Breast Cancer (NeAT-BC) Open
Background: Needs assessment tools may be used to guide the optimisation of cancer survivorship services. We sought to develop and validate a dual-language needs assessment tool for women with breast cancer. Methods: The study comprised tw…