Nur Diyana Md Nasir
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View article: Molecular pathobiology of breast fibroepithelial tumours
Molecular pathobiology of breast fibroepithelial tumours Open
View article: Tumours of the nipple – evidence gaps mapped from the fifth edition of the WHO classification of tumours of the breast: preliminary results
Tumours of the nipple – evidence gaps mapped from the fifth edition of the WHO classification of tumours of the breast: preliminary results Open
View article: A New Hierarchy of Research Evidence for Tumor Pathology: A Delphi Study to Define Levels of Evidence in Tumor Pathology
A New Hierarchy of Research Evidence for Tumor Pathology: A Delphi Study to Define Levels of Evidence in Tumor Pathology Open
The hierarchy of evidence is a fundamental concept in evidence-based medicine, but existing models can be challenging to apply in laboratory-based health care disciplines, such as pathology, where the types of evidence and contexts are sig…
View article: Phyllodes tumour evidence gaps mapped from the 5th edition of the WHO classification of tumours of the breast
Phyllodes tumour evidence gaps mapped from the 5th edition of the WHO classification of tumours of the breast Open
Aims Breast phyllodes tumours (PTs) are a rare subset of fibroepithelial neoplasms categorised into benign, borderline, and malignant grades according to the World Health Organization (WHO) Classification of Tumours (WCTs). In this report,…
View article: A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers—Analytical validation and performance evaluation with clinical samples
A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers—Analytical validation and performance evaluation with clinical samples Open
Introduction: A well-validated diagnostic assay with curated biomarkers complements clinicopathological factors to facilitate early diagnosis and ensure timely treatment delivery. This study focuses on an Asian-centric cancer diagnostic as…
View article: Therapeutic and immunomodulatory potential of pazopanib in malignant phyllodes tumor
Therapeutic and immunomodulatory potential of pazopanib in malignant phyllodes tumor Open
View article: Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing
Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing Open
View article: Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma Open
Angiosarcomas are rare, clinically aggressive tumors with limited treatment options and a dismal prognosis. We analyzed angiosarcomas from 68 patients, integrating information from multiomic sequencing, NanoString immuno-oncology profiling…
View article: Morphologic and genetic heterogeneity in breast fibroepithelial lesions—a comprehensive mapping study
Morphologic and genetic heterogeneity in breast fibroepithelial lesions—a comprehensive mapping study Open
View article: Counting Mitoses With Digital Pathology in Breast Phyllodes Tumors
Counting Mitoses With Digital Pathology in Breast Phyllodes Tumors Open
Context.— Mitotic count is an important histologic criterion for grading and prognostication in phyllodes tumors (PTs). Counting mitoses is a routine practice for pathologists evaluating neoplasms, but different microscopes, variable field…
View article: Genetics and genomics of breast fibroadenomas
Genetics and genomics of breast fibroadenomas Open
Fibroadenomas of the breast are benign fibroepithelial tumours most frequently encountered in women of reproductive age, although they may be diagnosed at any age. The fibroadenoma comprises a proliferation of both stromal and epithelial c…
View article: MED12 protein expression in breast fibroepithelial lesions: correlation with mutation status and oestrogen receptor expression
MED12 protein expression in breast fibroepithelial lesions: correlation with mutation status and oestrogen receptor expression Open
Aims Recent reports have identified recurrent MED12 somatic mutations in fibroadenomas and phyllodes tumours. The frequency and type of somatic mutations were noted to be similar to those of uterine leiomyomas. We aimed to investigate prot…
View article: <i>MED12</i> is frequently mutated in breast phyllodes tumours: a study of 112 cases
<i>MED12</i> is frequently mutated in breast phyllodes tumours: a study of 112 cases Open
Aim To determine the frequency of MED12 mutations in a series of 112 breast phyllodes tumours, and to correlate the findings with clinicopathological parameters and survival outcomes. Methods Phyllodes tumours from the Department of Pathol…