Nur Izzah Md Fadilah
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View article: Harnessing Plant Bioactive Compounds in Biomaterial Scaffolds for Advanced Wound Healing: A Comprehensive Review
Harnessing Plant Bioactive Compounds in Biomaterial Scaffolds for Advanced Wound Healing: A Comprehensive Review Open
Wound healing remains a significant clinical challenge due to antibiotic-resistant pathogens, persistent inflammation, oxidative stress, and impaired tissue regeneration. Conventional therapies are often inadequate, necessitating alternati…
View article: Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review
Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review Open
Wound healing is a complex and dynamic process that requires the coordination of cellular, molecular, and physiological events to restore tissue integrity. Despite notable advances in treatment strategies, optimizing healing outcomes, part…
View article: A Scoping Review of Pathogenesis, Current Treatments, and Novel Approaches for Vitiligo
A Scoping Review of Pathogenesis, Current Treatments, and Novel Approaches for Vitiligo Open
Background Vitiligo is a chronic skin disorder characterized by loss of melanocytes, causing depigmentation and psychological distress. Its pathogenesis is complex and multifactorial, involving genetic predisposition, autoimmune, oxidative…
View article: Kelulut Honey-Incorporated Hybrid Gelatin-PVA Hydrogel for Wound Healing: Fabrication and In Vitro Characterization
Kelulut Honey-Incorporated Hybrid Gelatin-PVA Hydrogel for Wound Healing: Fabrication and In Vitro Characterization Open
Hydrogels are attractive biomaterials for skin replacement and tissue regeneration, offering advantages over split-skin grafts for large or irregular wounds. Honey-containing hydrogels are of particular interest, combining honey’s natural …
View article: Antimicrobial Peptides in Wound Healing and Skin Regeneration: Dual Roles in Immunity and Microbial Defense
Antimicrobial Peptides in Wound Healing and Skin Regeneration: Dual Roles in Immunity and Microbial Defense Open
Although penicillin transformed antibiotic therapy, rising antimicrobial resistance (AMR) has limited its effectiveness, creating a need for new approaches in wound healing. Antimicrobial peptides (AMPs) are promising candidates due to the…
View article: Hybrid Adhesive Hydrogel Patch Containing Genipin-Crosslinked Gelatin–Hyaluronic Acid for Future Use in Atopic Dermatitis
Hybrid Adhesive Hydrogel Patch Containing Genipin-Crosslinked Gelatin–Hyaluronic Acid for Future Use in Atopic Dermatitis Open
Hydrogel patches have gained significant attention in wound healing applications as they are similar to hydrogel dressings due to their moisture-retentive properties, biocompatibility, and ability to promote tissue regeneration. In this st…
View article: Physicochemical Characterization of Injectable Genipin-Crosslinked Gelatin–Kelulut Honey Hydrogels for Future Cutaneous Tissue Loss
Physicochemical Characterization of Injectable Genipin-Crosslinked Gelatin–Kelulut Honey Hydrogels for Future Cutaneous Tissue Loss Open
Chronic wounds, particularly those associated with conditions like diabetes, present significant challenges in healthcare due to prolonged healing and high susceptibility to infections. This study investigates the development of injectable…
View article: A Comprehensive Review of Honey-Containing Hydrogel for Wound Healing Applications
A Comprehensive Review of Honey-Containing Hydrogel for Wound Healing Applications Open
Honey has long been recognized for its medicinal properties, particularly in wound healing. Recent advancements in material science have led to the development of honey-containing hydrogels, combining the natural healing properties of hone…
View article: Physicochemical properties of gelatin/hyaluronic acid printed hydrogel and incorporated with thymoquinone: In Vitro evaluation of biocompatibility for wound healing
Physicochemical properties of gelatin/hyaluronic acid printed hydrogel and incorporated with thymoquinone: In Vitro evaluation of biocompatibility for wound healing Open
Wound healing is a multifaceted biological process that necessitates the development of advanced materials that can effectively support tissue regeneration and repair. The fabrication of bioengineered wound dressings has evolved significan…
View article: Flavonoids as Natural Anti-Inflammatory Agents in the Atopic Dermatitis Treatment
Flavonoids as Natural Anti-Inflammatory Agents in the Atopic Dermatitis Treatment Open
Eczema is a complex autoimmune condition characterised mainly by inflammation and skin lesions along with physical and psychological comorbidities. Although there have been significant advances in understanding the mechanisms behind atopic…
View article: Asiaticoside-Loaded Multifunctional Bioscaffolds for Enhanced Hyperglycemic Wound Healing
Asiaticoside-Loaded Multifunctional Bioscaffolds for Enhanced Hyperglycemic Wound Healing Open
The review explores the potential of asiaticoside-loaded bioscaffolds to improve the management of hyperglycemic wounds, particularly diabetic foot ulcers (DFUs). Asiaticoside, sourced from Centella asiatica, possesses properties that addr…
View article: Fabrication and Evaluation of Dissolving Hyaluronic Acid Microneedle Patches for Minimally Invasive Transdermal Drug Delivery by Nanoimprinting
Fabrication and Evaluation of Dissolving Hyaluronic Acid Microneedle Patches for Minimally Invasive Transdermal Drug Delivery by Nanoimprinting Open
Transdermal drug delivery minimizes pain and provides a controlled, stable release of drugs, but its effectiveness is limited by the skin’s natural barriers. Microneedles overcome this problem, enabling minimally invasive drug delivery. Mi…
View article: Current Insight of Peptide-Based Hydrogels for Chronic Wound Healing Applications: A Concise Review
Current Insight of Peptide-Based Hydrogels for Chronic Wound Healing Applications: A Concise Review Open
Chronic wounds present a substantial healthcare obstacle, marked by an extended healing period that can persist for weeks, months, or even years. Typically, they do not progress through the usual phases of healing, which include hemostasis…
View article: Injectable Gelatin–Palmitoyl–GDPH Hydrogels as Bioinks for Future Cutaneous Regeneration: Physicochemical Characterization and Cytotoxicity Assessment
Injectable Gelatin–Palmitoyl–GDPH Hydrogels as Bioinks for Future Cutaneous Regeneration: Physicochemical Characterization and Cytotoxicity Assessment Open
Tissue engineering and regenerative medicine have made significant breakthroughs in creating complex three-dimensional (3D) constructs that mimic human tissues. This progress is largely driven by the development of hydrogels, which enable …
View article: Thymoquinone-Incorporated CollaGee Biomatrix: A Promising Approach for Full-Thickness Wound Healing
Thymoquinone-Incorporated CollaGee Biomatrix: A Promising Approach for Full-Thickness Wound Healing Open
Wound infection is the leading cause of delayed wound healing. Despite ongoing research, the ideal treatment for full-thickness skin wounds is yet to be achieved. Skin tissue engineering provides an alternative treatment, with the potentia…
View article: Application of 3D-Printed Bioinks in Chronic Wound Healing: A Scoping Review
Application of 3D-Printed Bioinks in Chronic Wound Healing: A Scoping Review Open
Chronic wounds, such as diabetic foot ulcers, pressure ulcers, and venous ulcers, pose significant clinical challenges and burden healthcare systems worldwide. The advent of 3D bioprinting technologies offers innovative solutions for enhan…
View article: Functionalised Sodium–Carboxymethylcellulose–Collagen Bioactive Bilayer as an Acellular Skin Substitute for Future Use in Diabetic Wound Management: The Evaluation of Physicochemical, Cell Viability, and Antibacterial Effects
Functionalised Sodium–Carboxymethylcellulose–Collagen Bioactive Bilayer as an Acellular Skin Substitute for Future Use in Diabetic Wound Management: The Evaluation of Physicochemical, Cell Viability, and Antibacterial Effects Open
The wound healing mechanism is dynamic and well-orchestrated; yet, it is a complicated process. The hallmark of wound healing is to promote wound regeneration in less time without invading skin pathogens at the injury site. This study deve…
View article: Antibacterial compounds-incorporated functional biomaterials for chronic wound healing application via 3D bioprinting: The mechanism of action
Antibacterial compounds-incorporated functional biomaterials for chronic wound healing application via 3D bioprinting: The mechanism of action Open
Wounds represent a critical issue in the healthcare industry since they are highly susceptible to infections that in turn lead to more serious complications. With bacterial infections gradually growing to be a challenge to wound healing, f…
View article: Effect of Multiple-Cycle Collections of Conditioned Media from Different Cell Sources towards Fibroblasts in In Vitro Wound Healing Model
Effect of Multiple-Cycle Collections of Conditioned Media from Different Cell Sources towards Fibroblasts in In Vitro Wound Healing Model Open
Conditioned media refers to a collection of the used cell culture media. The goal of this study was to evaluate the possible impacts of different conditioned media collected across a number of cycles on the fibroblast proliferation, migrat…
View article: Progress in Wound-Healing Products Based on Natural Compounds, Stem Cells, and MicroRNA-Based Biopolymers in the European, USA, and Asian Markets: Opportunities, Barriers, and Regulatory Issues
Progress in Wound-Healing Products Based on Natural Compounds, Stem Cells, and MicroRNA-Based Biopolymers in the European, USA, and Asian Markets: Opportunities, Barriers, and Regulatory Issues Open
Wounds are breaks in the continuity of the skin and underlying tissues, resulting from external causes such as cuts, blows, impacts, or surgical interventions. Countless individuals suffer minor to severe injuries, with unfortunate cases e…
View article: Discovery of bioactive peptides as therapeutic agents for skin wound repair
Discovery of bioactive peptides as therapeutic agents for skin wound repair Open
Short sequences of amino acids called peptides have a wide range of biological functions and the potential to treat a number of diseases. Bioactive peptides can be derived from different sources, including marine organisms, and synthetic d…
View article: Progress in Wound Healing Products based on Natural Compounds, Stem Cells and MicroRNA-based Biopolymers in the European, USA, and Asian Markets: Opportunities, Barriers, and Regulatory Issues
Progress in Wound Healing Products based on Natural Compounds, Stem Cells and MicroRNA-based Biopolymers in the European, USA, and Asian Markets: Opportunities, Barriers, and Regulatory Issues Open
Wounds are breaks in the continuity of the skin and the underlying tissues, due to external causes, such as cuts, blows and impacts, or even, during surgical interventions. Millions of people suffer minor or serious injuries, sometimes end…
View article: Progress in Wound Healing Products Based on Natural Compounds, Stem Cells and MicroRNA-Based Biopolymers in the European, USA, and Asian Markets: Opportunities, Barriers, and Regulatory Issues
Progress in Wound Healing Products Based on Natural Compounds, Stem Cells and MicroRNA-Based Biopolymers in the European, USA, and Asian Markets: Opportunities, Barriers, and Regulatory Issues Open
Wounds are breaks in the continuity of the skin and the underlying tissues, due to external causes, such as cuts, blows and impacts, or even, during surgical interventions. Millions of people suffer minor or serious injuries, sometimes end…
View article: Biological Safety Assessments of High-Purified Ovine Collagen Type I Biomatrix for Future Therapeutic Product: International Organisation for Standardisation (ISO) and Good Laboratory Practice (GLP) Settings
Biological Safety Assessments of High-Purified Ovine Collagen Type I Biomatrix for Future Therapeutic Product: International Organisation for Standardisation (ISO) and Good Laboratory Practice (GLP) Settings Open
Wound care management is incredibly challenging for chronic injuries, despite the availability of various types of wound care products in the market. However, most current wound-healing products do not attempt to mimic the extracellular ma…
View article: Functionalised-biomatrix for wound healing and cutaneous regeneration: future impactful medical products in clinical translation and precision medicine
Functionalised-biomatrix for wound healing and cutaneous regeneration: future impactful medical products in clinical translation and precision medicine Open
Skin tissue engineering possesses great promise in providing successful wound injury and tissue loss treatments that current methods cannot treat or achieve a satisfactory clinical outcome. A major field direction is exploring bioscaffolds…
View article: Sustainable Approach of Functional Biomaterials–Tissue Engineering for Skin Burn Treatment: A Comprehensive Review
Sustainable Approach of Functional Biomaterials–Tissue Engineering for Skin Burn Treatment: A Comprehensive Review Open
Burns are a widespread global public health traumatic injury affecting many people worldwide. Non-fatal burn injuries are a leading cause of morbidity, resulting in prolonged hospitalization, disfigurement, and disability, often with resul…
View article: Antioxidant Biomaterials in Cutaneous Wound Healing and Tissue Regeneration: A Critical Review
Antioxidant Biomaterials in Cutaneous Wound Healing and Tissue Regeneration: A Critical Review Open
Natural-based biomaterials play an important role in developing new products for medical applications, primarily in cutaneous injuries. A large panel of biomaterials with antioxidant properties has revealed an advancement in supporting and…
View article: Characterization of Dual-Layer Hybrid Biomatrix for Future Use in Cutaneous Wound Healing
Characterization of Dual-Layer Hybrid Biomatrix for Future Use in Cutaneous Wound Healing Open
A skin wound without immediate treatment could delay wound healing and may lead to death after severe infection (sepsis). Any interruption or inappropriate normal wound healing, mainly in these wounds, commonly resulted in prolonged and ex…
View article: The Discovery and Development of Natural-Based Biomaterials with Demonstrated Wound Healing Properties: A Reliable Approach in Clinical Trials
The Discovery and Development of Natural-Based Biomaterials with Demonstrated Wound Healing Properties: A Reliable Approach in Clinical Trials Open
Current research across the globe still focuses strongly on naturally derived biomaterials in various fields, particularly wound care. There is a need for more effective therapies that will address the physiological deficiencies underlying…
View article: Characterization and Cytocompatibility of Collagen–Gelatin–Elastin (CollaGee) Acellular Skin Substitute towards Human Dermal Fibroblasts: In Vitro Assessment
Characterization and Cytocompatibility of Collagen–Gelatin–Elastin (CollaGee) Acellular Skin Substitute towards Human Dermal Fibroblasts: In Vitro Assessment Open
Full-thickness skin wounds have become a serious burden to patients, medical care, and the socio-economic environment. The development of a safe and effective acellular skin substitute that can rapidly restore intact physiological skin is …