Oluwafemi Adeleke Ojo
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View article: Harnessing nanoparticles for phytochemical delivery: a comprehensive review of safety and therapeutic potential
Harnessing nanoparticles for phytochemical delivery: a comprehensive review of safety and therapeutic potential Open
Nanoparticle encapsulation has emerged as a relevant technology with the potential to revolutionize multiple fields, including medicine, food technology, cosmetics, and environmental monitoring. This review discusses the fundamental aspect…
View article: Effects of genetic polymorphism in susceptibility to schistosomiasis infection and adverse treatment outcomes
Effects of genetic polymorphism in susceptibility to schistosomiasis infection and adverse treatment outcomes Open
Schistosomiasis is a serious tropical disease that is undiagnosed (Neglected tropical disease -NTD). The only disease with a more detrimental socio-economic impact than its causative agent is malaria. Over 250 million individuals are prese…
View article: Application of genetic scissoring in the management of genetically related diseases
Application of genetic scissoring in the management of genetically related diseases Open
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology has emerged as a groundbreaking tool for genome editing, revolutionizing the management of genetic diseases. Its precision, efficiency, and adaptability enable t…
View article: Performance Indices, Carcass Characteristics, Organs, and Thermal Stress Responses of Broiler Chicken Exposed to Dietary Betaine Hydrochloride During Hot Season
Performance Indices, Carcass Characteristics, Organs, and Thermal Stress Responses of Broiler Chicken Exposed to Dietary Betaine Hydrochloride During Hot Season Open
The impact of varied levels of betaine hydrochloride on performance indices, carcass characteristics and thermal stress of broilers during the hot season was assessed by this study. 180 day-old broiler chicks were distributed into 5 treatm…
View article: Antibacterial and antifungal effects of Hippocratea velutina (Afzel.) leaves and its constituents: Experimental and computational approaches
Antibacterial and antifungal effects of Hippocratea velutina (Afzel.) leaves and its constituents: Experimental and computational approaches Open
Hippocratea velutina (HV) Afzel's application in wound care suggests its antimicrobial property, although no scientific data confirms its efficacy. Therefore, the antibacterial and antifungal properties of HV leaves are assessed in this st…
View article: Ameliorative effect of Hibiscus sabdariffa leaf flavonoid extract on the PSA/CEA/AKT/MMP-9 signaling pathway in benign prostatic hyperplasia-induced rats
Ameliorative effect of Hibiscus sabdariffa leaf flavonoid extract on the PSA/CEA/AKT/MMP-9 signaling pathway in benign prostatic hyperplasia-induced rats Open
Benign prostatic hypertrophy (BPH) is a prevalent condition affecting the prostate gland of elderly men. This study investigated the effects of H. sabdariffa leaf flavonoid extracts on BPH induction in rats. Thirty-six male Wistar rats wer…
View article: Exploring the Multifunctional Agents of Flavonoid‐Rich Beet Leaf Extracts: Insights From Experimental and Computational Studies
Exploring the Multifunctional Agents of Flavonoid‐Rich Beet Leaf Extracts: Insights From Experimental and Computational Studies Open
This study evaluated the multifunctional ability of Beta vulgaris leaves in dual therapy for Alzheimer's disease (AD) and type 2 diabetes (T2D). Flavonoid‐rich extracts of B. vulgaris leaves (FREBVL) were tested for their antidiabetic prop…
View article: Bioprospection of indigenous herbal formulations for diabetes care: in vitro, network pharmacology, and molecular dynamics studies
Bioprospection of indigenous herbal formulations for diabetes care: in vitro, network pharmacology, and molecular dynamics studies Open
Background Herbal formulations have garnered significant interest from researchers for their potential antidiabetic effects. However, scientific validation of their efficacy and understanding of their mechanisms of action have limited thei…
View article: Sustaining the power grid: Breakthroughs and challenges in long-duration energy storage
Sustaining the power grid: Breakthroughs and challenges in long-duration energy storage Open
The rapid shift towards renewable energy sources, particularly solar and wind power, is both a triumph and a challenge for modern energy grids. While these resources promise a cleaner future, their inherent intermittency threatens grid sta…
View article: Protective effects of flavonoid-rich extracts from Hibiscus sabdariffa leaves on streptozotocin-induced testicular damage in rats
Protective effects of flavonoid-rich extracts from Hibiscus sabdariffa leaves on streptozotocin-induced testicular damage in rats Open
Objective: This study investigated the protective effects of flavonoid-rich extracts from Hibiscus sabdariffa leaves on testicular cumulative reproductive function biomarkers in streptozotocin (STZ)-induced diabetic rats. Methods: Rats wer…
View article: Comparative profiling of secondary metabolites and antidiabetic properties of Anogeissus leiocarpus (DC.) Guill. & Perr. (Combretaceae) extracts
Comparative profiling of secondary metabolites and antidiabetic properties of Anogeissus leiocarpus (DC.) Guill. & Perr. (Combretaceae) extracts Open
Background: Diabetes mellitus is a chronic metabolic condition which can result in severe long-term complications, and current treatments often have significant side effects. As a result, there is a growing interest in identifying novel α-…
View article: IoT-Enabled Energy Storage Systems For Renewable Energy Grid Integration
IoT-Enabled Energy Storage Systems For Renewable Energy Grid Integration Open
The rapid growth of renewable energy sources, such as solar and wind, has introduced significant challenges to grid reliability due to their intermittent and unpredictable nature. Energy storage systems (ESS) have emerged as a vital soluti…
View article: The Relationships between the Biochemical Processes of Diabetes and Urinary and Genital Tract Alterations
The Relationships between the Biochemical Processes of Diabetes and Urinary and Genital Tract Alterations Open
This abstract examines the complex interactions that occur between the metabolic processes linked to diabetes and the resulting changes in the genital and urinary tracts. Diabetes mellitus is a metabolic disease that affects several physio…
View article: IoT-Driven Predictive Maintenance For Wind Turbines
IoT-Driven Predictive Maintenance For Wind Turbines Open
Wind turbines are critical components of renewable energy infrastructure, yet their maintenance poses significant challenges due to unpredictable failures and high operational costs. This paper presents an IoT-driven predictive maintenance…
View article: Smart Grids And IOT-Enabled Renewable Energy Integration
Smart Grids And IOT-Enabled Renewable Energy Integration Open
Over the past decades, the power system has undergone significant transformations. However, it faces multiple challenges, including rising electricity demand, power losses, grid failures, and a lack of innovative technology. Additionally, …
View article: Enhancing Power Grid Resilience Through Energy Storage And Demand Response
Enhancing Power Grid Resilience Through Energy Storage And Demand Response Open
The resilience of power grids is increasingly essential in the face of climate change, extreme weather events, and the growing complexity of energy systems. To ensure continuous electricity supply during outages and stress events, utilitie…
View article: PHYTOCHEMICAL SCREENING, ANTIBACTERIAL AND ANTIOXIDANT STUDIES OF HYOSCYAMUS AUREUS L. LEAF EXTRACT
PHYTOCHEMICAL SCREENING, ANTIBACTERIAL AND ANTIOXIDANT STUDIES OF HYOSCYAMUS AUREUS L. LEAF EXTRACT Open
Hyoscyamus aureus L belongs to the Family, Solanaceae and it has been used both in ancient times and in modern medical practice for the treatment of certain disease conditions such as the relief of pain, inflammation, constipation, palpita…
View article: Ferroptosis as the new approach to cancer therapy
Ferroptosis as the new approach to cancer therapy Open
Cancer is characterized by unregulated cell proliferation, evasion of apoptosis, and a propensity for metastasis, making it a leading cause of morbidity and mortality globally. Major challenges in cancer treatment include drug resistance a…
View article: Effects of germinated pigeon pea inclusion on the chemical composition and sensory properties of maize-based pudding
Effects of germinated pigeon pea inclusion on the chemical composition and sensory properties of maize-based pudding Open
This study evaluated the effects of germinated pigeon pea addition on chemical and sensory properties of maize-pigeon pea pudding. The maize grains were cleaned, dried, milled, and sieved to produce maize flour while the pigeon peas were s…
View article: Endocrine-disrupting chemicals (EDCs) and epigenetic regulation in embryonic development: Mechanisms, impacts, and emerging trends
Endocrine-disrupting chemicals (EDCs) and epigenetic regulation in embryonic development: Mechanisms, impacts, and emerging trends Open
Endocrine-disrupting chemicals (EDCs) are prevalent ecological pollutants that interfere with hormonal systems and pose serious health risks to the public, especially during critical developmental windows. Well-known EDCs, such as bispheno…
View article: Advances in nanomaterials for lithium-ion batteries: Enhancing energy density and lifespan
Advances in nanomaterials for lithium-ion batteries: Enhancing energy density and lifespan Open
With revolutionary gains in energy density, stability, and lifetime, nanomaterials are driving the development of lithium-ion batteries (LIBs). The need for improved performance has prompted extensive study into the incorporation of nanoma…
View article: Antioxidant activity of <i>Brachiaria sabia</i> and <i>Brachiaria marandu</i> and molecular docking of constituents targeting insulin-like growth factor 1 receptor (IGF-1R) for cancer treatment
Antioxidant activity of <i>Brachiaria sabia</i> and <i>Brachiaria marandu</i> and molecular docking of constituents targeting insulin-like growth factor 1 receptor (IGF-1R) for cancer treatment Open
The methanol extracts of Brachiaria sabia, and Brachiaria marandu leaves were evaluated for its ability to scavenge free radicals, reduce ferric iron, and function as an iron chelator. The extracts were subjected to HPLC analysis. The two …
View article: Application, benefits, and limitations of herbal garment in natural medicine administration
Application, benefits, and limitations of herbal garment in natural medicine administration Open
Natural dyes are becoming increasingly common for practical finishes that encourage an eco-friendly lifestyle. Natural dyes are renewable materials safe for the environment and do not cause toxicity, cancer, or allergic reactions. Transder…
View article: Effect of <i>Hibiscus sabdariffa</i> L. leaf flavonoid-rich extract on Nrf-2 and HO-1 pathways in liver damage of streptozotocin-induced diabetic rats
Effect of <i>Hibiscus sabdariffa</i> L. leaf flavonoid-rich extract on Nrf-2 and HO-1 pathways in liver damage of streptozotocin-induced diabetic rats Open
This study investigated the effects of flavonoid-rich extract from Hibiscus sabdariffa L. (Malvaceae) leaves on liver damage in streptozotocin-induced diabetic rats by evaluating various biochemical parameters, including the molecular gene…
View article: Beta vulgaris L. beetroot protects against iron-induced liver injury by restoring antioxidant pathways and regulating cellular functions
Beta vulgaris L. beetroot protects against iron-induced liver injury by restoring antioxidant pathways and regulating cellular functions Open
Beta vulgaris L. is a root vegetable that is consumed mainly as a food additive. This study aimed to describe the protective effect of B. vulgaris on Fe2+-mediated oxidative liver damage through in vitro, ex vivo, and in silico studies to …
View article: Brine shrimp lethality and antioxidant property of <i>Lagenaria breviflora</i> (Benth.) Roberty fruit crude extract and fractions
Brine shrimp lethality and antioxidant property of <i>Lagenaria breviflora</i> (Benth.) Roberty fruit crude extract and fractions Open
Background: Oxidative injury plays a pivotal impact in the development of human diseases, and it is a major component of the pathophysiology of several inflammation-linked human medical disorders. Objective: The focus of this study was to …
View article: Energy metabolism and spermatogenesis
Energy metabolism and spermatogenesis Open
Infertility has become a significant health burden around the globe as it is believed that 15 % of married couples struggle with infertility, with half of the problem accrued to the male. The issue of male infertility could be traced to in…