Okelue E Okobi
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View article: Temporal and Regional Trends in the Crude Prevalence of Diabetes in Canada From 2000 to 2022: An Ecological Study Using Aggregated Surveillance Data
Temporal and Regional Trends in the Crude Prevalence of Diabetes in Canada From 2000 to 2022: An Ecological Study Using Aggregated Surveillance Data Open
Background Diabetes remains a significant public health concern in Canada, with rising prevalence rates observed over recent decades. Understanding geographic and demographic patterns is essential for informing targeted prevention and reso…
View article: GLP-1 Agonists and Cardiovascular Risk Markers in U.S. Adults: National Health and Nutrition Examination Survey (NHANES) 2011-2018
GLP-1 Agonists and Cardiovascular Risk Markers in U.S. Adults: National Health and Nutrition Examination Survey (NHANES) 2011-2018 Open
GLP-1 receptor agonist use was associated with lower systolic blood pressure among adults with overweight or obesity. These findings highlight population-level associations that may inform future research on the cardiometabolic impact of G…
View article: Impact of Health Insurance Status on HbA1c Control Among United States Adults With Type 2 Diabetes: A Cross-Sectional Analysis of Nationally Representative Data
Impact of Health Insurance Status on HbA1c Control Among United States Adults With Type 2 Diabetes: A Cross-Sectional Analysis of Nationally Representative Data Open
Health insurance alone may not ensure optimal glycemic control. Addressing broader social and clinical factors is essential to improving outcomes in diabetes care.
View article: Association Between Physical Activity Frequency and Depression Severity Among Adults in the United States With Mild to Moderate Depression: A Cross-Sectional Analysis Using National Health and Nutrition Examination Survey (NHANES) Data
Association Between Physical Activity Frequency and Depression Severity Among Adults in the United States With Mild to Moderate Depression: A Cross-Sectional Analysis Using National Health and Nutrition Examination Survey (NHANES) Data Open
Physical activity frequency was not independently associated with depression severity. Socioeconomic and demographic factors were stronger predictors, highlighting the importance of addressing social determinants in depression intervention…
View article: Incidence of Dementia in Canada: A National Trend Analysis of Newly Diagnosed Cases
Incidence of Dementia in Canada: A National Trend Analysis of Newly Diagnosed Cases Open
Although the age-standardized incidence of newly diagnosed dementia in Canada declined modestly between 2007 and 2022, substantial sex, age, and regional disparities remain. The findings emphasize the need for ongoing investment in dementi…
View article: Comparative Effectiveness of Management Strategies for Stage IV Prostate Cancer: A Narrative Review
Comparative Effectiveness of Management Strategies for Stage IV Prostate Cancer: A Narrative Review Open
Stage IV prostate cancer (PCa) refers to a disease that has metastasized beyond the prostate gland to distant sites, such as bones, visceral organs, or non-regional lymph nodes. While early attempts at curative therapy were occasionally ma…
View article: Trends in Glucagon-Like Peptide-1 Agonist Use and BMI Among Obese Adults With Type 2 Diabetes: Analysis of the 2010-2015 National Ambulatory Medical Care Survey (NAMCS), Adjusted for Cardiovascular Comorbidity.
Trends in Glucagon-Like Peptide-1 Agonist Use and BMI Among Obese Adults With Type 2 Diabetes: Analysis of the 2010-2015 National Ambulatory Medical Care Survey (NAMCS), Adjusted for Cardiovascular Comorbidity. Open
Background and objective Glucagon-like peptide-1 (GLP-1) receptor agonists are increasingly used to manage type 2 diabetes (T2D) and promote weight loss; however, their real-world use remains undercharacterized. The objective of this study…
View article: Impact of Blood Pressure Control on Stroke and Myocardial Infarction Risk in Hypertensive Patients With and Without Diabetes: A Narrative Review
Impact of Blood Pressure Control on Stroke and Myocardial Infarction Risk in Hypertensive Patients With and Without Diabetes: A Narrative Review Open
Hypertension (HTN) is a well-acknowledged and modifiable risk factor that significantly increases the risk of cardiovascular disease. Left uncontrolled, HTN may result in severe complications, including myocardial infarction and stroke. Al…
View article: Asthma-Related ED Visits Among Children in the United States: A Cross-Sectional Analysis of Associated Factors Using the National Hospital Ambulatory Medical Care Survey (NHAMCS), 2006-2020
Asthma-Related ED Visits Among Children in the United States: A Cross-Sectional Analysis of Associated Factors Using the National Hospital Ambulatory Medical Care Survey (NHAMCS), 2006-2020 Open
Background Asthma remains a leading cause of ED visits among children in the United States. Despite clinical advancements, disparities in asthma care and control persist, particularly among socioeconomically and racially marginalized popul…
View article: Obesity, Depression, and Antidepressant Use: Analyzing Metabolic Side Effects in US Adults Using the National Health and Nutrition Examination Survey (NHANES)
Obesity, Depression, and Antidepressant Use: Analyzing Metabolic Side Effects in US Adults Using the National Health and Nutrition Examination Survey (NHANES) Open
While antidepressant use was not independently associated with obesity, it was linked to specific metabolic alterations, with effects varying by gender and depression status. These findings underscore the importance of monitoring metabolic…
View article: Ultra-Processed Food Intake, Obesity, and Mood Disorders: An Epidemiological Study From the National Health and Nutrition Examination Survey (NHANES) 2005 to 2018 Data
Ultra-Processed Food Intake, Obesity, and Mood Disorders: An Epidemiological Study From the National Health and Nutrition Examination Survey (NHANES) 2005 to 2018 Data Open
Higher UPF intake is associated with increased depressive symptoms but not with obesity after controlling for confounding variables. These findings emphasize the potential mental health implications of ultra-processed dietary patterns and …
View article: Prevalence and Hospitalization Trends of Cardiovascular Disease in Diabetic Populations: An Analysis of the United States Diabetes Surveillance System (USDSS) Data From 2000 to 2022
Prevalence and Hospitalization Trends of Cardiovascular Disease in Diabetic Populations: An Analysis of the United States Diabetes Surveillance System (USDSS) Data From 2000 to 2022 Open
Although crude hospitalization rates for CVD among adults with diabetes declined over two decades, the absolute burden of disease rose in step with the expanding diabetic population. Significant disparities by age, sex, and race persist. T…
View article: Relationship Between Health Insurance Status and Frequency of Routine Medical Checkups
Relationship Between Health Insurance Status and Frequency of Routine Medical Checkups Open
Health insurance coverage is a strong predictor of routine healthcare utilization. Expanding access to insurance may substantially improve the uptake of preventive services, particularly among underserved populations.
View article: Association Between Antidepressant Use and Hemoglobin A1c Levels in Adults With Comorbid Type 2 Diabetes Mellitus and Depression
Association Between Antidepressant Use and Hemoglobin A1c Levels in Adults With Comorbid Type 2 Diabetes Mellitus and Depression Open
Antidepressant use was not significantly associated with HbA1c levels in U.S. adults with T2DM and depression. Further research is needed to explore the effects of specific antidepressant types and behavioral factors on glycemic control.
View article: Demographic and Clinical Epidemiology of Irritable Bowel Syndrome in U.S. Community Health Centers: A Cross-Sectional Analysis of the 2022–2023 National Ambulatory Medical Care Survey
Demographic and Clinical Epidemiology of Irritable Bowel Syndrome in U.S. Community Health Centers: A Cross-Sectional Analysis of the 2022–2023 National Ambulatory Medical Care Survey Open
Background Irritable bowel syndrome (IBS) is a prevalent, burdensome gastrointestinal disorder frequently encountered in primary care. However, its demographic and comorbidity patterns in community health center (CHC) settings remain under…
View article: Protective Factors Against Hypertension: A Retrospective Population-Based Analysis of Resilience in High-Risk Groups
Protective Factors Against Hypertension: A Retrospective Population-Based Analysis of Resilience in High-Risk Groups Open
Background While risk factors for hypertension (HTN) are well-known, some high-risk individuals remain free of the condition, suggesting the presence of protective factors. Objective The objective of this study is to identify protective fa…
View article: Association Between Suicide-Related Outcomes and Primary Care Outpatient Visits: Impact of Mental Health Screening and Interventions
Association Between Suicide-Related Outcomes and Primary Care Outpatient Visits: Impact of Mental Health Screening and Interventions Open
Suicide remains a major public health concern, although most individuals who experience suicidal thoughts and ideations have contacted primary care shortly before committing suicide. This systematic review highlights the importance of suic…