O. Köhn
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View article: Thermal annealing of radiation dosimetry fibres
Thermal annealing of radiation dosimetry fibres Open
The thermal annealing of P-doped radiation dosimetry fibres was investigated to increase their operation time, especially at accelerators. We have shown that a regeneration of irradiated fibres is possible at least 20 times while keeping t…
View article: Radiomics-Based Image Phenotyping of Kidney Apparent Diffusion Coefficient Maps: Preliminary Feasibility & Efficacy
Radiomics-Based Image Phenotyping of Kidney Apparent Diffusion Coefficient Maps: Preliminary Feasibility & Efficacy Open
Given the central role of interstitial fibrosis in disease progression in chronic kidney disease (CKD), a role for diffusion-weighted MRI has been pursued. We evaluated the feasibility and preliminary efficacy of using radiomic features to…
View article: Fused Filament Fabrication Additive Manufacturing: Mechanical Response of Polyethylene Terephthalate Glycol
Fused Filament Fabrication Additive Manufacturing: Mechanical Response of Polyethylene Terephthalate Glycol Open
The additive manufacturing (AM) fused filament fabrication (FFF) technology is widely used today with different kinds of thermoplastic materials, including polyethylene terephthalate glycol (PETG). One of the major problems of parts produc…
View article: Supplementary Material for: Medullary Blood Oxygen Level-Dependent MRI Index (R2*) is Associated with Annual Loss of Kidney Function in Moderate CKD
Supplementary Material for: Medullary Blood Oxygen Level-Dependent MRI Index (R2*) is Associated with Annual Loss of Kidney Function in Moderate CKD Open
Background: The estimated glomerular filtration rate (eGFR) is frequently used to monitor progression of kidney disease. Multiple values have to be obtained, sometimes over years to determine the rate of decline in kidney function. Recent …
View article: Novel Use of Premixed Dialysate Bags during Water Supply Interruption in Acute Hospital Setting
Novel Use of Premixed Dialysate Bags during Water Supply Interruption in Acute Hospital Setting Open
Patients on dialysis are exposed to large amounts of water during conventional intermittent hemodialysis; hence, there are strict regulations regarding the quality of water used to prepare dialysate. Occasionally, water systems fail due to…
View article: Medullary Blood Oxygen Level-Dependent MRI Index (R2*) is Associated with Annual Loss of Kidney Function in Moderate CKD
Medullary Blood Oxygen Level-Dependent MRI Index (R2*) is Associated with Annual Loss of Kidney Function in Moderate CKD Open
Background: The estimated glomerular filtration rate (eGFR) is frequently used to monitor progression of kidney disease. Multiple values have to be obtained, sometimes over years to determine the rate of decline in kidney function. Recent …
View article: Cortical Perfusion and Tubular Function as Evaluated by Magnetic Resonance Imaging Correlates with Annual Loss in Renal Function in Moderate Chronic Kidney Disease
Cortical Perfusion and Tubular Function as Evaluated by Magnetic Resonance Imaging Correlates with Annual Loss in Renal Function in Moderate Chronic Kidney Disease Open
Background: Chronic hypoxia is a well-recognized factor in the pathogenesis of chronic kidney disease (CKD). Loss of microcirculation is thought to lead to enhanced renal hypoxia, which in turn results in the development of fibrosis, a hal…
View article: Irradiation tests on optical fibers below 20 k
Irradiation tests on optical fibers below 20 k Open
Up to now no comparison of radiation test results on optical fibers at room temperature and below 150 K was done. However, in some applications much lower temperatures will define the environment, for example at cryogenic accelerator insta…
View article: Three‐Stream, Bicarbonate‐Based Hemodialysis Solution Delivery System Revisited: With an Emphasis on Some Aspects of Acid‐Base Principles
Three‐Stream, Bicarbonate‐Based Hemodialysis Solution Delivery System Revisited: With an Emphasis on Some Aspects of Acid‐Base Principles Open
Hemodialysis patients can acquire buffer base (i.e., bicarbonate and buffer base equivalents of certain organic anions) from the acid and base concentrates of a three‐stream, dual‐concentrate, bicarbonate‐based, dialysis solution delivery …
View article: Evaluation of Renal Blood Flow in Chronic Kidney Disease Using Arterial Spin Labeling Perfusion Magnetic Resonance Imaging
Evaluation of Renal Blood Flow in Chronic Kidney Disease Using Arterial Spin Labeling Perfusion Magnetic Resonance Imaging Open
These results support the use of ASL in the evaluation of renal blood flow in patients with moderate level of CKD. Whether these measurements can identify subjects at risk of progressive CKD requires further longitudinal follow-up.
View article: Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND)
Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND) Open
The identified set of AIMs, which include American Indian parental allele frequencies, may be particularly useful for estimating genetic admixture in populations from the Americas. Failure to balance information in maximum likelihood, poly…
View article: Additional file 1: of Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND)
Additional file 1: of Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND) Open
RCWilliamsContrastEU_AI450AIMs. (XLSX 60 kb)
View article: Additional file 3: of Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND)
Additional file 3: of Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND) Open
RCWilliamsContrastAI_AF400AIMS. (XLSX 55 kb)
View article: Additional file 6: of Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND)
Additional file 6: of Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND) Open
RCWilliamsBalanced975AIMs. (XLSX 120 kb)
View article: Additional file 2: of Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND)
Additional file 2: of Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND) Open
RCWilliamsContrastEU_AF450AIMs. (XLSX 60 kb)
View article: Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)
Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND) Open
Diabetic kidney disease (DKD) is the most common etiology of chronic kidney disease (CKD) in the industrialized world and accounts for much of the excess mortality in patients with diabetes mellitus. Approximately 45% of U.S. patients with…