Olga Maria Nardone
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View article: Bowel Urgency Improvement Correlates With Clinical, Biochemical, and Intestinal Ultrasound Improvements in Inflammatory Bowel Disease: A Cross Sectional Multicenter Study
Bowel Urgency Improvement Correlates With Clinical, Biochemical, and Intestinal Ultrasound Improvements in Inflammatory Bowel Disease: A Cross Sectional Multicenter Study Open
Background Bowel urgency (BU) is reported by over 80% of patients with ulcerative colitis (UC) and 60% of those with Crohn's disease (CD). However, the impact of advanced therapies on BU has not been consistently evaluated. Objectives To a…
View article: Comparative analysis of sporadic, IBD-associated, early-onset and late-onset colorectal cancer: a systematic review and meta-analysis
Comparative analysis of sporadic, IBD-associated, early-onset and late-onset colorectal cancer: a systematic review and meta-analysis Open
Background: Colorectal cancer (CRC) remains a multifaceted disease with variations in aetiology, clinical presentation and prognostic factors. Objectives: This study explores the features and outcomes of sporadic (S-CRC), inflammatory bowe…
View article: Heterogeneity in Histological Evaluation of Microscopic Colitis in Randomized Clinical Trials: An Umbrella Review
Heterogeneity in Histological Evaluation of Microscopic Colitis in Randomized Clinical Trials: An Umbrella Review Open
Background The diagnosis of microscopic colitis (MC) is based on endoscopic biopsy with histological assessment. Histological outcomes (remission, response or improvement) are important treatment targets in clinical trials. Although a subs…
View article: Digital biomarkers and artificial intelligence: a new frontier in personalized management of inflammatory bowel disease
Digital biomarkers and artificial intelligence: a new frontier in personalized management of inflammatory bowel disease Open
Background and aims Artificial intelligence (AI) is rapidly gaining traction in gastroenterology, particularly in the management of inflammatory bowel disease (IBD). Given the complexity of IBD care, AI offers the potential to enhance diag…
View article: Non-invasive spectroscopic analytical molecular neural network-based profiling of saliva and endoscopic tissue biopsy for inflammatory bowel disease diagnosis
Non-invasive spectroscopic analytical molecular neural network-based profiling of saliva and endoscopic tissue biopsy for inflammatory bowel disease diagnosis Open
Current gold-standard for diagnosing and monitoring inflammatory bowel disease (IBD) is a costly, invasive and painful procedure. Recently, saliva analysis been emerging as a non-invasive biofluid due to its correlation with blood constitu…
View article: Advancing Inflammatory Bowel Disease-Driven Colorectal Cancer Management: Molecular Insights and Endoscopic Breakthroughs Towards Precision Medicine
Advancing Inflammatory Bowel Disease-Driven Colorectal Cancer Management: Molecular Insights and Endoscopic Breakthroughs Towards Precision Medicine Open
Colorectal cancer (CRC) is a serious complication of inflammatory bowel disease (IBD), significantly contributing to increased mortality and health care burden. Although advances in IBD management have led to a decline in CRC incidence, it…
View article: Artificial Intelligence in Advancing Inflammatory Bowel Disease Management: Setting New Standards
Artificial Intelligence in Advancing Inflammatory Bowel Disease Management: Setting New Standards Open
Introduction: Artificial intelligence (AI) is increasingly being applied to improve the diagnosis and management of inflammatory bowel disease (IBD). Aims and Methods: We conducted a narrative review of the literature on AI applications in…
View article: Venous and arterial thromboembolism in out-patients with inflammatory bowel disease: a single center study
Venous and arterial thromboembolism in out-patients with inflammatory bowel disease: a single center study Open
Background: Patients affected by inflammatory bowel diseases (IBD), namely Crohn's disease (CD) and ulcerative colitis (UC), are at risk for thromboembolic events (TE). Patients with active/relapsing disease and those needing hospitalizati…
View article: The Effectiveness of Medical Therapies for Joint, Skin and Eye Extraintestinal Manifestations in IBD—An Umbrella Review
The Effectiveness of Medical Therapies for Joint, Skin and Eye Extraintestinal Manifestations in IBD—An Umbrella Review Open
Background Extraintestinal manifestations (EIMs) occur commonly in patients with inflammatory bowel disease (IBD), affecting joints, skin, eyes and other organs, and contributing to morbidity and long‐term disability. Aims To synthesise ev…
View article: Ischemic ulcers do not significantly impact endoscopic recurrence score in Crohn's disease: A multicenter comparative study after right-side colectomy
Ischemic ulcers do not significantly impact endoscopic recurrence score in Crohn's disease: A multicenter comparative study after right-side colectomy Open
The prevalence of anastomotic (presumed ischemic) ulcers in CC patients is very low, but if shifted into the POR of CD, this is not representative of a real diagnostic matter. Prospective, multicenter, and direct comparative studies are ne…
View article: Reducing diagnostic delays of extraintestinal manifestations in inflammatory bowel disease: a comparative study of a multidisciplinary outpatient clinic versus conventional referral specialists
Reducing diagnostic delays of extraintestinal manifestations in inflammatory bowel disease: a comparative study of a multidisciplinary outpatient clinic versus conventional referral specialists Open
Background: Managing extraintestinal manifestations (EIMs) in inflammatory bowel disease (IBD) patients remains challenging due to considerable heterogeneity in diagnostic criteria and the lack of a standardised definition and validated di…
View article: P0925 Risk of postoperative Crohn’s disease recurrence in patients smoking e-cigarettes and heat-not-burn tobacco products: a multicenter retrospective study
P0925 Risk of postoperative Crohn’s disease recurrence in patients smoking e-cigarettes and heat-not-burn tobacco products: a multicenter retrospective study Open
Background Tobacco is a known risk factor for Crohn’s disease (CD) recurrence after surgery. However, the impact of electronic cigarettes (or vape) and heat-no-burn tobacco products on post-operative recurrence is unknown. Methods We condu…
View article: P0457 Food avoidance, eating disorders and disability in Inflammatory Bowel Disease: a cross-sectional analysis of risk factors
P0457 Food avoidance, eating disorders and disability in Inflammatory Bowel Disease: a cross-sectional analysis of risk factors Open
Background Patients with inflammatory bowel disease (IBD) often adjust their diet to manage symptoms and avoid perceived food triggers. However, these habits can increase the risk of eating disorders (ED) and avoidant/restrictive food inta…
View article: Rediscovering histology – the application of artificial intelligence in inflammatory bowel disease histologic assessment
Rediscovering histology – the application of artificial intelligence in inflammatory bowel disease histologic assessment Open
Integrating artificial intelligence (AI) into histologic disease assessment is transforming the management of inflammatory bowel disease (IBD). AI-aided histology enables precise, objective evaluations of disease activity by analysing whol…
View article: Artificial intelligence to revolutionize IBD clinical trials: a comprehensive review
Artificial intelligence to revolutionize IBD clinical trials: a comprehensive review Open
Integrating artificial intelligence (AI) into clinical trials for inflammatory bowel disease (IBD) has potential to be transformative to the field. This article explores how AI-driven technologies, including machine learning (ML), natural …
View article: P0271 Overweight is associated with low mediterranean diet adherence and increased disability in patients with Inflammatory Bowel Disease
P0271 Overweight is associated with low mediterranean diet adherence and increased disability in patients with Inflammatory Bowel Disease Open
Background The prevalence of obesity in inflammatory bowel disease (IBD) has risen, with 15–40% of adults classified as obese and an additional 20–40% as overweight1. Poor dietary habits and sedentary lifestyles contribute to overweight an…
View article: Inflammatory Bowel Diseases and Nephropathies: Exploring the Gut–Kidney Axis
Inflammatory Bowel Diseases and Nephropathies: Exploring the Gut–Kidney Axis Open
Inflammatory bowel disease (IBD) can extend beyond the gastrointestinal tract, affecting extraintestinal organs and significantly increasing morbidity and mortality. Despite early studies revealing kidney involvement in nearly a quarter of…
View article: Heterogeneity of definition of upper gastrointestinal tract in different guidelines of Crohn's disease: A scoping review
Heterogeneity of definition of upper gastrointestinal tract in different guidelines of Crohn's disease: A scoping review Open
Crohn's Disease (CD) can affect any part of the gastrointestinal (GI) tract, including the upper GI tract (UGIT). However, the definitions and classifications of upper GI CD (UGICD) vary. We conducted a scoping review to explore how UGIT a…
View article: Efficacy and safety of Advanced Combination Treatment in immune-mediated inflammatory disease: A systematic review and meta-analysis of randomized controlled trials
Efficacy and safety of Advanced Combination Treatment in immune-mediated inflammatory disease: A systematic review and meta-analysis of randomized controlled trials Open
ACT did not offer clinical benefit in patients with rheumatological IMIDs and resulted in higher rate adverse events in rheumatoid arthritis. ACT may offer clinical benefit without a clear safety signal in patients with IBD, but further tr…
View article: Sexual dysfunctions in inflammatory bowel disease: role of Mediterranean diet and quality of life
Sexual dysfunctions in inflammatory bowel disease: role of Mediterranean diet and quality of life Open
Background Dietary factors and chronic gastrointestinal diseases are frequent determinants of sexual dysfunctions (SD). Whether inflammatory bowel diseases (IBD) are associated with SD is not well known as well as the role of diet and qual…
View article: Advancing perioperative optimization in Crohn's disease surgery with machine learning predictions
Advancing perioperative optimization in Crohn's disease surgery with machine learning predictions Open
This editorial offers commentary on the article which aimed to forecast the likelihood of short-term major postoperative complications (Clavien-Dindo grade ≥ III), including anastomotic fistula, intra-abdominal sepsis, bleeding, and intest…
View article: Insights into Probiotic Prescription among Gastroenterologists and Other Healthcare Professionals: Evidence from an Italian Survey
Insights into Probiotic Prescription among Gastroenterologists and Other Healthcare Professionals: Evidence from an Italian Survey Open
Background: Probiotics, which are live microorganisms that provide health benefits, have been extensively studied for their various clinical applications. However, despite their potential, high-quality data supporting their use in several …
View article: Endocytoscopy with automated multispectral intestinal barrier pathology imaging for assessment of deep healing to predict outcomes in ulcerative colitis
Endocytoscopy with automated multispectral intestinal barrier pathology imaging for assessment of deep healing to predict outcomes in ulcerative colitis Open
Endoscopy newsdetails and guide tissue sampling combined with automated barrier protein evaluation
View article: Predicting Outcome after Acute Severe Ulcerative Colitis: A Contemporary Review and Areas for Future Research
Predicting Outcome after Acute Severe Ulcerative Colitis: A Contemporary Review and Areas for Future Research Open
Acute Severe Ulcerative Colitis (ASUC) is a severe form of ulcerative colitis relapse which requires hospitalization and intensive medical intervention to avoid colectomy. The timely recognition of patients at risk of corticosteroid failur…
View article: Insights into disability and psycho-social care of patients with inflammatory bowel disease
Insights into disability and psycho-social care of patients with inflammatory bowel disease Open
In recent years, the concept of disability has increasingly garnered attention as a crucial long-term target of inflammatory bowel disease (IBD) management. The treatment paradigm has changed dramatically from full control of the disease (…