Explanipedia

Evaluating the impact of a structured medication optimisation review on prescribing patterns and bleeding risk among patients prescribed direct oral anticoagulants (DOACs): a difference-in-differences study Open

Elizabeth Camacho, O. W. Butters, Konstantinos Daras, Jennifer Downing, S. V. Lynch , et al. · 2025

Objective To evaluate the safety of implementing structured medication optimisation reviews (SMORs) for patients with atrial fibrillation (AF) prescribed direct oral anticoagulants (DOACs). SMORs aimed to improve quality of care and facili…

How can mobility data be used to evaluate urban green space interventions? A synthetic control analysis of wildflower planting in Liverpool, UK (2021–2022) Open

Mark Green, Wenjing Zhang, Polly Moseley, Richard Scott, O. W. Butters , et al. · 2025

dsBase: 'DataSHIELD' Server Side Base Functions Open

Paul R. Burton, Rebecca Wilson, O. W. Butters, Patricia Ryser-Welch, Alex Westerberg , et al. · 2025

DataSHIELD: mitigating disclosure risk in a multi-site federated analysis platform Open

Demetris Avraam, Rebecca Wilson, Noemi Aguirre Chan, Soumya Banerjee, Tom Bishop , et al. · 2024

Motivation The validity of epidemiologic findings can be increased using triangulation, i.e. comparison of findings across contexts, and by having sufficiently large amounts of relevant data to analyse. However, access to data is often con…

Creating a learning health system to include environmental determinants of health: The <span>GroundsWell</span> experience Open

Sarah Rodgers, Rebecca Geary, Roberto Villegas‐Diaz, Iain Buchan, Hannah Burnett , et al. · 2024

Introduction Policies aiming to prevent ill health and reduce health inequalities need to consider the full complexity of health systems, including environmental determinants. A learning health system that incorporates environmental factor…

GroundsWell: Community-engaged and data-informed systems transformation of Urban Green and Blue Space for population health – a new initiative Open

Ruth F. Hunter, Sarah Rodgers, J. Hilton, Mike Clarke, Leandro Martin Totaro Garcia , et al. · 2022

Natural environments, such as parks, woodlands and lakes, have positive impacts on health and wellbeing. Urban Green and Blue Spaces (UGBS), and the activities that take place in them, can significantly influence the health outcomes of all…

825 DEVELOPMENT OF THE ANTICHOLINERGIC MEDICATION INDEX (ACMI) Open

Kate Best, Sarah Alderson, David P Alldred, Laura Bonnet, Iain Buchan , et al. · 2022

Introduction Medications with Anticholinergic (AC) properties, are prescribed to treat a range of conditions. Older people are increasingly likely to be prescribed multiple AC medications, but are also more likely to experience unwanted ad…

PUblications Metadata Augmentation (PUMA) pipeline Open

O. W. Butters, Rebecca Wilson, Hugh Garner, Thomas Burton · 2021

Cohort studies collect, generate and distribute data over long periods of time – often over the lifecourse of their participants. It is common for these studies to host a list of publications (which can number many thousands) on their webs…

PUMA pipeline output Open

O. W. Butters, Rebecca Wilson, Hugh Garner, Thomas Burton · 2021

Output of the PUMA (PUblications Metadata Augmentation) software pipeline which takes a list of journal articles and augments it with metadata from external sources. This augmented metadata is then processed to generate data files and an e…

PUMA pipeline output Open

O. W. Butters, Rebecca Wilson, Hugh Garner, Thomas Burton · 2021

Output of the PUMA (PUblications Metadata Augmentation) software pipeline which takes a list of journal articles and augments it with metadata from external sources. This augmented metadata is then processed to generate data files and an e…

Privacy preserving data visualizations Open

Demetris Avraam, Rebecca Wilson, O. W. Butters, Thomas Burton, Christos Nicolaides , et al. · 2021

PUblications Metadata Augmentation (PUMA) pipeline Open

O. W. Butters, Rebecca Wilson, Hugh Garner, Thomas Burton · 2020

Cohort studies collect, generate and distribute data over long periods of time – often over the lifecourse of their participants. It is common for these studies to host a list of publications (which can number many thousands) on their webs…

Recognizing, reporting and reducing the data curation debt of cohort studies Open

O. W. Butters, Rebecca Wilson, Paul R. Burton · 2020

Good data curation is integral to cohort studies, but it is not always done to a level necessary to ensure the longevity of the data a study holds. In this opinion paper, we introduce the concept of data curation debt—the data curation equ…

Automation of cleaning and reconstructing residential address histories to assign environmental exposures in longitudinal studies Open

Daniela Fecht, Kevin Garwood, O. W. Butters, John Henderson, Paul Elliott , et al. · 2019

Background We have developed an open-source ALgorithm for Generating Address Exposures (ALGAE) that cleans residential address records to construct address histories and assign spatially-determined exposures to cohort participants. The fir…

Generation of a cleaned dataset listing Avon Longitudinal Study of Parents And Children peer-reviewed publications to 2015 Open

O. W. Butters, Amran Ismail, Sue Ellen Thompson, Rebecca Wilson · 2018

Birth cohort studies generate huge amounts of data, and as a consequence are a source of many peer reviewed publications. We have taken the list of publications from the Avon Longitudinal Study of Parents and Children UK birth cohort, filt…

ALSPAC peer reviewed publications 1989-2015 Open

O. W. Butters, Amran Ismail, Sue Ellen Thompson, Rebecca Wilson · 2018

List of peer reviewed publications generated from the Avon Longitudinal Study of Parents and Children (ALSPAC) data from 1989 to the end of 2015.

ALSPAC peer reviewed publications 1989-2015 Open

O. W. Butters, Amran Ismail, Sue Thompson, Rebecca Wilson · 2018

List of peer reviewed publications generated from the Avon Longitudinal Study of Parents and Children (ALSPAC) data from 1989 to the end of 2015.

Better governance, better access: practising responsible data sharing in the METADAC governance infrastructure Open

Madeleine J. Murtagh, Mwenza Blell, O. W. Butters, Lorraine Cowley, Edward S. Dove , et al. · 2018

Background Genomic and biosocial research data about individuals is rapidly proliferating, bringing the potential for novel opportunities for data integration and use. The scale, pace and novelty of these applications raise a number of urg…

DataSHIELD – New Directions and Dimensions Open

Rebecca Wilson, O. W. Butters, Demetris Avraam, James Baker, Jonathan Tedds , et al. · 2017

In disciplines such as biomedicine and social sciences, sharing and combining sensitive individual-level data is often prohibited by ethical-legal or governance constraints and other barriers such as the control of intellectual property or…

Privacy protected text analysis in DataSHIELD Open

Rebecca Wilson, O. W. Butters, Demetris Avraam, Andrew Turner, Paul Burton · 2017

ObjectivesDataSHIELD (www.datashield.ac.uk) was born of the requirement in the biomedical and social sciences to co-analyse individual patient data (microdata) from different sources, without disclosing identity or sensitive information. U…

The ECOUTER methodology for stakeholder engagement in translational research Open

Madeleine J. Murtagh, Joel T. Minion, Andrew Turner, Rebecca Wilson, Mwenza Blell , et al. · 2017

Digital Methodology to implement the ECOUTER engagement process Open

Rebecca Wilson, O. W. Butters, Thomas A. Clark, Joel T. Minion, Andrew Turner , et al. · 2017

ECOUTER (Employing COnceptual schema for policy and Translation E in Research – French for ‘to listen’ – is a new stakeholder engagement method incorporating existing evidence to help participants draw upon their own knowledge of cognate i…

PUMA: First results Open

Becca Wilson, O. W. Butters, Hugh Garner, Tom Burton, Amran Ismail · 2017

Initial results showing outputs from the PUMA pipeline.

The Biomedical Research Infrastructure Software as a Service Kit (BRISSKit): technical description Open

O. W. Butters, Shajid Issa, Jeff Lusted, Malcolm Newbury, Russ Parsloe , et al. · 2016

With biomedical research becoming ever more computationally intensive, the challenge is to find sophisticated software tools that can keep pace with new requirements, while still being easy to use and secure. We describe a technical implem…

i2b2-install-procedures v1.0 Open

O. W. Butters, Jeff Lusted, Saj Issa · 2016

Shell scripts for installing i2b2

Digital methodology to implement the ECOUTER engagement process Open

Rebecca Wilson, O. W. Butters, Thomas A. Clark, Joel T. Minion, Andrew Turner , et al. · 2016

ECOUTER (Employing COnceptUal schema for policy and Translation Engagement in Research) – French for ‘to listen’ – is a new stakeholder engagement method incorporating existing evidence to help participants draw upon their own knowledge of…

ecouter: ECOUTER implementation scripts Open

beccawilson, O. W. Butters, Becca Wilson, Thomas A. Clark, O. W. Butters · 2016

A collection of scripts to assist in ECOUTER (http://www.bristol.ac.uk/ecouter) implementation utilising the free mindmapping software Mind42 (http://www.mind42.com). We share these to encourage use of the ECOUTER engagement process.

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