Odaro J. Huckstep
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View article: Exercise Improves Myocardial Deformation But Not Cardiac Structure in Preterm-Born Adults
Exercise Improves Myocardial Deformation But Not Cardiac Structure in Preterm-Born Adults Open
View article: Correction: Distinct circle of willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study
Correction: Distinct circle of willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study Open
View article: Distinct Circle of Willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study
Distinct Circle of Willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study Open
Background Preterm birth (< 37 weeks’ gestation) alters cerebrovascular development due to the premature transition from a foetal to postnatal circulatory system, with potential implications for future cerebrovascular health. This study ai…
View article: Improvement in myocardial deformation but not structural indices in adults born preterm following a prescribed aerobic exercise intervention: a randomized clinical trial
Improvement in myocardial deformation but not structural indices in adults born preterm following a prescribed aerobic exercise intervention: a randomized clinical trial Open
Background People born preterm (<37 weeks’ gestation) have a potentially adverse cardiac phenotype that progresses with blood pressure elevation. We sought to determine whether preterm-born adults with elevated and stage 1 hypertension exh…
View article: Designing a Wastewater-Based Epidemiology Study at the U.S. Air Force Academy: Using Severe Acute Respiratory Syndrome Coronavirus 2 to Test a Sentinel System for Early Disease Outbreak Detection
Designing a Wastewater-Based Epidemiology Study at the U.S. Air Force Academy: Using Severe Acute Respiratory Syndrome Coronavirus 2 to Test a Sentinel System for Early Disease Outbreak Detection Open
Introduction The presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) in wastewater has been proposed as a sentinel surveillance epidemiological tool for detection of infectious disease at a community level and as a comp…
View article: Aerobic exercise increases brain vessel lumen size and blood flow in young adults with elevated blood pressure. Secondary analysis of the TEPHRA randomized clinical trial
Aerobic exercise increases brain vessel lumen size and blood flow in young adults with elevated blood pressure. Secondary analysis of the TEPHRA randomized clinical trial Open
View article: Aerobic Exercise Training Response in Preterm-Born Young Adults with Elevated Blood Pressure and Stage 1 Hypertension: A Randomized Clinical Trial
Aerobic Exercise Training Response in Preterm-Born Young Adults with Elevated Blood Pressure and Stage 1 Hypertension: A Randomized Clinical Trial Open
Rationale: Premature birth is an independent predictor of long-term cardiovascular risk. Individuals affected are reported to have a lower rate of [Formula: see text]o2 at peak exercise intensity ([Formula: see text]o
View article: Effect of moderate to high intensity aerobic exercise on blood pressure in young adults: The TEPHRA open, two-arm, parallel superiority randomized clinical trial
Effect of moderate to high intensity aerobic exercise on blood pressure in young adults: The TEPHRA open, two-arm, parallel superiority randomized clinical trial Open
Wellcome Trust, British Heart Foundation, National Institute for Health Research, Oxford Biomedical Research Centre.
View article: Estimates of Single Dose and Full Dose BNT162b2 Vaccine Effectiveness among USAF Academy cadets, 1 Mar - 1 May 2021
Estimates of Single Dose and Full Dose BNT162b2 Vaccine Effectiveness among USAF Academy cadets, 1 Mar - 1 May 2021 Open
Beginning in early March 2021 and continuing through May 2021, the USAF Academy began vaccinating cadets for protection against the SARS-CoV-2 virus with the BNT162b2 (Pfizer-BioNTech) mRNA vaccine. During this period, vaccination of the a…
View article: Proteomic Signature of Dysfunctional Circulating Endothelial Colony‐Forming Cells of Young Adults
Proteomic Signature of Dysfunctional Circulating Endothelial Colony‐Forming Cells of Young Adults Open
Background A subpopulation of endothelial progenitor cells called endothelial colony‐forming cells (ECFCs) may offer a platform for cellular assessment in clinical studies because of their remarkable angiogenic and expansion potentials in …
View article: Association of Systolic Blood Pressure Elevation With Disproportionate Left Ventricular Remodeling in Very Preterm-Born Young Adults
Association of Systolic Blood Pressure Elevation With Disproportionate Left Ventricular Remodeling in Very Preterm-Born Young Adults Open
Preterm-born individuals have higher blood pressure with an increased risk of hypertension by young adulthood, as well as potentially adverse cardiac remodeling even when normotensive. To what extent blood pressure elevation affects left v…
View article: Left atrial strain predicts cardiovascular response to exercise in young adults with suboptimal blood pressure
Left atrial strain predicts cardiovascular response to exercise in young adults with suboptimal blood pressure Open
Young adults with suboptimal blood pressure have a reduced left ventricular systolic response to exercise, which can be predicted by their left atrial booster pump function at rest. Echocardiographic measures of left atrial function may pr…
View article: Association of Systolic Blood Pressure Elevation With Disproportionate Left Ventricular Remodeling in Very Preterm-Born Young Adults
Association of Systolic Blood Pressure Elevation With Disproportionate Left Ventricular Remodeling in Very Preterm-Born Young Adults Open
Preterm-born adults have a unique LV structure and function that worsens with systolic blood pressure elevation. Additional primary prevention strategies specifically targeting cardiovascular risk reduction in this population may be warran…
View article: Multimodality Imaging Demonstrates Reduced Right-Ventricular Function Independent of Pulmonary Physiology in Moderately Preterm-Born Adults
Multimodality Imaging Demonstrates Reduced Right-Ventricular Function Independent of Pulmonary Physiology in Moderately Preterm-Born Adults Open
View article: Variations in Cardiovascular Structure, Function, and Geometry in Midlife Associated With a History of Hypertensive Pregnancy
Variations in Cardiovascular Structure, Function, and Geometry in Midlife Associated With a History of Hypertensive Pregnancy Open
Hypertensive pregnancy is associated with increased maternal cardiovascular risk in later life. A range of cardiovascular adaptations after pregnancy have been reported to partly explain this risk. We used multimodality imaging to identify…
Impaired myocardial reserve underlies reduced exercise capacity and heart rate recovery in preterm-born young adults Open
View article: P374 Prediction of an adverse cardiovascular response to physical exercise from resting echocardiography imaging in young adults with suboptimal blood pressure
P374 Prediction of an adverse cardiovascular response to physical exercise from resting echocardiography imaging in young adults with suboptimal blood pressure Open
Funding Acknowledgements British Heart Foundation (BHF) grants (PG/13/58/30397) Background Young adults with mildly elevated blood pressure are less likely to engage with physical activity. This may be because early hypertension alters myo…
View article: Trial of exercise to prevent HypeRtension in young adults (TEPHRA) a randomized controlled trial: Study protocol 11 Medical and Health Sciences 1117 Public Health and Health Services
Trial of exercise to prevent HypeRtension in young adults (TEPHRA) a randomized controlled trial: Study protocol 11 Medical and Health Sciences 1117 Public Health and Health Services Open
View article: Trial of Exercise to Prevent HypeRtension in young Adults (TEPHRA) a randomized controlled trial: study protocol
Trial of Exercise to Prevent HypeRtension in young Adults (TEPHRA) a randomized controlled trial: study protocol Open
View article: Association of Cardiovascular Risk Factors With MRI Indices of Cerebrovascular Structure and Function and White Matter Hyperintensities in Young Adults
Association of Cardiovascular Risk Factors With MRI Indices of Cerebrovascular Structure and Function and White Matter Hyperintensities in Young Adults Open
In this preliminary study involving young adults without clinical evidence of cerebrovascular disease, a greater number of modifiable cardiovascular risk factors at recommended levels was associated with higher cerebral vessel density and …
View article: Physiological Stress Elicits Impaired Left Ventricular Function in Preterm-Born Adults
Physiological Stress Elicits Impaired Left Ventricular Function in Preterm-Born Adults Open
Preterm-born young adults had impaired LV response to physiological stress when subjected to physical exercise, which suggested a reduced myocardial functional reserve that might help explain their increased risk of early heart failure. (Y…
View article: Impact of Cardiovascular Risk Factors on Cerebrovascular Structure and Perfusion in Young Adults
Impact of Cardiovascular Risk Factors on Cerebrovascular Structure and Perfusion in Young Adults Open
View article: P100 TRIAL OF EXERCISE TO PREVENT HYPERTENSION IN YOUNG ADULTS (TEPHRA): RATIONALE AND PROTOCOL
P100 TRIAL OF EXERCISE TO PREVENT HYPERTENSION IN YOUNG ADULTS (TEPHRA): RATIONALE AND PROTOCOL Open
Background: Hypertension or pre-hypertension in young adults is unusual and more often linked with an adverse family or pregnancy history, such as preterm birth, than hypertension which develops later in life1–4. Surprisingly, no trials ha…
View article: Invited Commentary: Hypertension During Pregnancy and Offspring Microvascular Structure—Insights From the Retinal Microcirculation
Invited Commentary: Hypertension During Pregnancy and Offspring Microvascular Structure—Insights From the Retinal Microcirculation Open
Human clinical studies as well as laboratory animal studies demonstrate that offspring of pregnancies affected by common complications, such as preeclampsia and preterm birth, display developmental phenotypes that relate distinctly to the …
View article: Will Exercise Advice Be Sufficient for Treatment of Young Adults With Prehypertension and Hypertension? A Systematic Review and Meta-Analysis
Will Exercise Advice Be Sufficient for Treatment of Young Adults With Prehypertension and Hypertension? A Systematic Review and Meta-Analysis Open
Previous studies report benefits of exercise for blood pressure control in middle age and older adults, but longer-term effectiveness in younger adults is not well established. We performed a systematic review and meta-analysis of publishe…