Oh‐Bin Kwon
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View article: <scp>HDAC4</scp>/5 Inhibitor, <scp>LMK</scp>‐235 Improves Animal Voluntary Movement in <scp>MPTP</scp>‐Induced Parkinson's Disease Model
<span>HDAC4</span>/5 Inhibitor, <span>LMK</span>‐235 Improves Animal Voluntary Movement in <span>MPTP</span>‐Induced Parkinson's Disease Model Open
Oxidation of dopamine can cause various side effects, which ultimately leads to cell death and contributes to Parkinson's disease (PD). To counteract dopamine oxidation, newly synthesized dopamine is quickly transported into vesicles via v…
View article: Prenatal treatment with corticosterone via maternal injection induces learning and memory impairments via delaying postsynaptic development in hippocampal <scp>CA1</scp> neurons of rats
Prenatal treatment with corticosterone via maternal injection induces learning and memory impairments via delaying postsynaptic development in hippocampal <span>CA1</span> neurons of rats Open
Previously, we reported that prenatal exposure to high corticosterone induced attention‐deficit hyperactivity disorder (ADHD)‐like behaviors with cognitive deficits after weaning. In the present study, cellular mechanisms underlying cortis…
View article: Dopaminergic cell protection and alleviation of neuropsychiatric disease symptoms by<scp>VMAT2</scp>expression through the class I<scp>HDAC</scp>inhibitor<scp>TC‐H</scp>106
Dopaminergic cell protection and alleviation of neuropsychiatric disease symptoms by<span>VMAT2</span>expression through the class I<span>HDAC</span>inhibitor<span>TC‐H</span>106 Open
The importance of vesicular monoamine transporter 2 (VMAT2) in dopamine regulation, which is considered crucial for neuropsychiatric disorders, is currently being studied. Moreover, the development of disease treatments using histone deace…
View article: Neuregulin-2 ablation results in dopamine dysregulation and severe behavioral phenotypes relevant to psychiatric disorders
Neuregulin-2 ablation results in dopamine dysregulation and severe behavioral phenotypes relevant to psychiatric disorders Open
Numerous genetic and functional studies implicate variants of Neuregulin-1 (NRG1) and its neuronal receptor ErbB4 in schizophrenia and many of its endophenotypes. Although the neurophysiological and behavioral phenotypes of NRG1 mutant mic…