Explanipedia

Correction: The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer Open

Rodrigo Entrialgo‐Cadierno, Cristina Cueto‐Ureña, Connor Welch, Iker Feliu, Irati Macaya , et al. · 2023

The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer Open

Rodrigo Entrialgo‐Cadierno, Cristina Cueto‐Ureña, Connor Welch, Iker Feliu, Irati Macaya , et al. · 2023

Data from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael P. Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Melanoma and other solid cancers are frequently resistant to chemotherapies based on DNA alkylating agents such as dacarbazine and temozolomide. As a consequence, clinical responses are generally poor. Such resistance is partly due to the …

Data from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael P. Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Melanoma and other solid cancers are frequently resistant to chemotherapies based on DNA alkylating agents such as dacarbazine and temozolomide. As a consequence, clinical responses are generally poor. Such resistance is partly due to the …

Supplementary Figure 4 from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael Peter Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Supplementary Figure 4. A, Western-blot showing the expression levels of the MMR enzymes MSH2, MLH1 and MSH6 in NET cell lines. B, GI50s for glioblastoma (GBM), pancreatic neuroendocrine (NET) and colorectal (CRC) cancer cell lines treated…

Supplementary Figure 4 from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael P. Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Supplementary Figure 4. A, Western-blot showing the expression levels of the MMR enzymes MSH2, MLH1 and MSH6 in NET cell lines. B, GI50s for glioblastoma (GBM), pancreatic neuroendocrine (NET) and colorectal (CRC) cancer cell lines treated…

Supplementary Figure 3 from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael P. Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Supplementary Figure 3. Western-blot showing the expression levels of the MMR enzymes MSH2, MLH1 and MSH6 in 12 melanoma cell lines.

Supplementary Figure 1 from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael P. Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Supplementary Figure 1. A, Colony formation assay 12-well plate layout. B, MGMT promoter methylation assay.

Supplementary Figure 2 from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael P. Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Supplementary Figure 2. A,Effect 0.25μM olaparib on the proliferation of 12 melanoma cell lines. B, GI50s for TMZ of 12 melanoma cell lines treated with or without olaparib. PF50s values are also shown. C, Colony formation of 6 MGMT+ve and…

Supplementary Figure 1 from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael Peter Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Supplementary Figure 1. A, Colony formation assay 12-well plate layout. B, MGMT promoter methylation assay.

Supplementary Figure 3 from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael Peter Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Supplementary Figure 3. Western-blot showing the expression levels of the MMR enzymes MSH2, MLH1 and MSH6 in 12 melanoma cell lines.

Supplementary Figure 5 from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael P. Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Supplementary Figure 5. A, Colony formation assay on WM98.1 clones expressing an empty vector (vector) or MGMT (MGMT) treated with TMZ with or without veliparib (ABT). B, GI50s of the same WM98.1 clones treated with MMS with our without ol…

Supplementary Figure 2 from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael Peter Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Supplementary Figure 2. A,Effect 0.25μM olaparib on the proliferation of 12 melanoma cell lines. B, GI50s for TMZ of 12 melanoma cell lines treated with or without olaparib. PF50s values are also shown. C, Colony formation of 6 MGMT+ve and…

Supplementary Figure 5 from MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide Open

Oihane Erice, Michael P. Smith, Rachel White, Ibai Goicoechea, Jorge Barriuso , et al. · 2023

Supplementary Figure 5. A, Colony formation assay on WM98.1 clones expressing an empty vector (vector) or MGMT (MGMT) treated with TMZ with or without veliparib (ABT). B, GI50s of the same WM98.1 clones treated with MMS with our without ol…

Figure S4 from LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth Open