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View article: Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat
Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat Open
Safe anaerobic metabolism Naked mole-rats live in large colonies deep underground in hypoxic conditions. Park et al. found that these animals fuel anaerobic glycolysis with fructose by a rewired pathway that avoids tissue damage (see the P…
View article: Highlights of the 1st Student Symposium on Computational Genomics
Highlights of the 1st Student Symposium on Computational Genomics Open
On 30 November 2016, over 70 junior researchers in computational biology from diverse countries met in Mainz, Germany, for the 1st Student Symposium on Computational Genomics. Overall, the symposium was a great success and featured four ou…
View article: Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat
Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat Open
The naked mole-rat is a subterranean rodent lacking several pain behaviors found in humans, rats, and mice. For example, nerve growth factor (NGF), an important mediator of pain sensitization, fails to produce thermal hyperalgesia in naked…