Olga Scudiero
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View article: Evaluation of DGBIs Prevalence (Rome IV Criteria) in Paediatric Patients with Obesity and Correlation with Inflammatory Markers
Evaluation of DGBIs Prevalence (Rome IV Criteria) in Paediatric Patients with Obesity and Correlation with Inflammatory Markers Open
Background Several studies demonstrated a link between obesity and Disorders of Gut-Brain Interaction (DGBIs). In patients with obesity, it has been shown an alteration of inflammation markers. The study aims to assess the prevalence of DG…
View article: Review of: "Case Report: Urinary Proteomic Analysis of Exercise-Induced Rhabdomyolysis with Acute Kidney Injury"
Review of: "Case Report: Urinary Proteomic Analysis of Exercise-Induced Rhabdomyolysis with Acute Kidney Injury" Open
View article: Effect of elite sport activity on salivary microbiota: The case of water polo
Effect of elite sport activity on salivary microbiota: The case of water polo Open
View article: How Does Physical Activity Modulate Hormone Responses?
How Does Physical Activity Modulate Hormone Responses? Open
Physical activity highly impacts the neuroendocrine system and hormonal secretion. Numerous variables, both those related to the individual, including genetics, age, sex, biological rhythms, nutritional status, level of training, intake of…
View article: Bacterial Porins and Their Procoagulant Role: Implication in the Pathophysiology of Several Thrombotic Complications during Sepsis
Bacterial Porins and Their Procoagulant Role: Implication in the Pathophysiology of Several Thrombotic Complications during Sepsis Open
The association between sepsis and thrombotic complications is still not well known. Different mechanisms have been shown to be involved in the sepsis-induced prothrombotic state, but clinical scenarios may differ. In this review, we have …
View article: Thrombosis and Thrombotic Risk in Athletes
Thrombosis and Thrombotic Risk in Athletes Open
The hemostatic system is characterized by a delicate balance between pro- and anticoagulant forces, and the smallest alteration can cause serious events such as hemorrhages or thrombosis. Although exercise has been shown to play a protecti…
View article: Positive effects of physical activity in autism spectrum disorder: how influences behavior, metabolic disorder and gut microbiota
Positive effects of physical activity in autism spectrum disorder: how influences behavior, metabolic disorder and gut microbiota Open
Autism spectrum disorder is a neurodevelopmental disorder characterized by social interactions and communication skills impairments that include intellectual disabilities, communication delays and self-injurious behaviors; often are presen…
View article: Evaluation of Antioxidant Defence Systems and Inflammatory Status in Basketball Elite Athletes
Evaluation of Antioxidant Defence Systems and Inflammatory Status in Basketball Elite Athletes Open
Intense physical activity can induce metabolic changes that modify specific biochemical biomarkers. In this scenario, the purpose of our study was to evaluate how intense physical activity can affect oxidative metabolism. Following this, f…
View article: Integrated Approach to Highlighting the Molecular Bases of a Deep Vein Thrombosis Event in an Elite Basketball Athlete
Integrated Approach to Highlighting the Molecular Bases of a Deep Vein Thrombosis Event in an Elite Basketball Athlete Open
Acute or intense exercise can result in metabolic imbalances, muscle injuries, or reveal hidden disorders. Laboratory medicine in sports is playing an increasingly crucial role in monitoring athletes’ health conditions. In this study, we d…
View article: Visceral adipose tissue and residual cardiovascular risk: a pathological link and new therapeutic options
Visceral adipose tissue and residual cardiovascular risk: a pathological link and new therapeutic options Open
Obesity is a heterogeneous disease that affects almost one-third of the global population. A clear association has been established between obesity and cardiovascular disease (CVD). However, CVD risk is known to be related more to the loca…
View article: Combined MITOchondrial-NUCLEAR (MITO-NUCLEAR) Analysis for Mitochondrial Diseases Diagnosis: Validation and Implementation of a One-Step NGS Method
Combined MITOchondrial-NUCLEAR (MITO-NUCLEAR) Analysis for Mitochondrial Diseases Diagnosis: Validation and Implementation of a One-Step NGS Method Open
Background: Next-generation sequencing (NGS) technology is revolutionizing diagnostic screening for mitochondrial diseases (MDs). Moreover, an investigation by NGS still requires analyzing the mitochondrial genome and nuclear genes separat…
View article: Modulation of Hormonal Homeostasis and Blood Biochemical Markers by Non-Hormonal Drugs
Modulation of Hormonal Homeostasis and Blood Biochemical Markers by Non-Hormonal Drugs Open
View article: The Impact of Physical Exercise on Obesity in a Cohort of Southern Italian Obese Children: Improvement in Cardiovascular Risk and Immune System Biomarkers
The Impact of Physical Exercise on Obesity in a Cohort of Southern Italian Obese Children: Improvement in Cardiovascular Risk and Immune System Biomarkers Open
Background: Childhood obesity (CO) is a serious medical condition affecting approximately 120 million children and adolescents worldwide. It is characterized by a persistent inflammatory state with inflammatory markers overexpressed, which…
View article: Diagnostic and Therapeutic Potential for HNP-1, HBD-1 and HBD-4 in Pregnant Women with COVID-19
Diagnostic and Therapeutic Potential for HNP-1, HBD-1 and HBD-4 in Pregnant Women with COVID-19 Open
Pregnancy is characterized by significant immunological changes and a cytokine profile, as well as vitamin deficiencies that can cause problems for the correct development of a fetus. Defensins are small antimicrobial peptides that are par…
View article: The Biological Role of Vitamins in Athletes’ Muscle, Heart and Microbiota
The Biological Role of Vitamins in Athletes’ Muscle, Heart and Microbiota Open
Physical activity, combined with adequate nutrition, is considered a protective factor against cardiovascular disease, musculoskeletal disorders, and intestinal dysbiosis. Achieving optimal performance requires a significantly high energy …
View article: 596<i> </i>Multidisciplinary in-depth investigation in a young athlete suffering from syncope caused by myocardial bridge
596<i> </i>Multidisciplinary in-depth investigation in a young athlete suffering from syncope caused by myocardial bridge Open
Aims Laboratory medicine along with genetic investigations are taking on an increasingly important role in monitoring athlete’s health conditions. Acute or intense exercise can lead to metabolic imbalances, muscle injuries, or can point up…
View article: Multidisciplinary In-Depth Investigation in a Young Athlete Suffering from Syncope Caused by Myocardial Bridge
Multidisciplinary In-Depth Investigation in a Young Athlete Suffering from Syncope Caused by Myocardial Bridge Open
Laboratory medicine, along with genetic investigations in sports medicine, is taking on an increasingly important role in monitoring athletes’ health conditions. Acute or intense exercise can result in metabolic imbalances, muscle injuries…
View article: Antimicrobial Peptides and Physical Activity: A Great Hope against COVID 19
Antimicrobial Peptides and Physical Activity: A Great Hope against COVID 19 Open
Antimicrobial peptides (AMPs), α- and β-defensins, possess antiviral properties. These AMPs achieve viral inhibition through different mechanisms of action. For example, they can: (i) bind directly to virions; (ii) bind to and modulate hos…
View article: Molecular Epidemiology of Mitochondrial Cardiomyopathy: A Search Among Mitochondrial and Nuclear Genes
Molecular Epidemiology of Mitochondrial Cardiomyopathy: A Search Among Mitochondrial and Nuclear Genes Open
Mitochondrial Cardiomyopathy (MCM) is a common manifestation of multi-organ Mitochondrial Diseases (MDs), occasionally present in non-syndromic cases. Diagnosis of MCM is complex because of wide clinical and genetic heterogeneity and requi…
View article: Effects of the COVID-19 Pandemic on Job Activity, Dietary Behaviours and Physical Activity Habits of University Population of Naples, Federico II-Italy
Effects of the COVID-19 Pandemic on Job Activity, Dietary Behaviours and Physical Activity Habits of University Population of Naples, Federico II-Italy Open
Coronaviruses (CoVs) are a large family of respiratory viruses that can cause mild to moderate illness. The new variant COVID-19 has started to spread rapidly since December 2019, posing a new threat to global health. To counter the spread…
View article: Exercise, Immune System, Nutrition, Respiratory and Cardiovascular Diseases during COVID-19: A Complex Combination
Exercise, Immune System, Nutrition, Respiratory and Cardiovascular Diseases during COVID-19: A Complex Combination Open
Coronaviruses (CoVs) represent a large family of RNA viruses that can infect different living species, posing a global threat to human health. CoVs can evade the immune response, replicate within the host, and cause a rapid immune compromi…
View article: Dietary Thiols: A Potential Supporting Strategy against Oxidative Stress in Heart Failure and Muscular Damage during Sports Activity
Dietary Thiols: A Potential Supporting Strategy against Oxidative Stress in Heart Failure and Muscular Damage during Sports Activity Open
Moderate exercise combined with proper nutrition are considered protective factors against cardiovascular disease and musculoskeletal disorders. However, physical activity is known not only to have positive effects. In fact, the achievemen…
View article: The Hidden Fragility in the Heart of the Athletes: A Review of Genetic Biomarkers
The Hidden Fragility in the Heart of the Athletes: A Review of Genetic Biomarkers Open
Sudden cardiac death (SCD) is a devastating event which can also affect people in apparent good health, such as young athletes. It is known that intense and continuous exercise along with a genetic background that predisposes a person to t…
View article: Molecular Basis of Inflammation in the Pathogenesis of Cardiomyopathies
Molecular Basis of Inflammation in the Pathogenesis of Cardiomyopathies Open
Cardiomyopathies (CMPs) represent a diverse group of heart muscle diseases, grouped into specific morphological and functional phenotypes. CMPs are associated with mutations in sarcomeric and non-sarcomeric genes, with several suspected ep…
View article: Urinary Biomarkers: Diagnostic Tools for Monitoring Athletes’ Health Status
Urinary Biomarkers: Diagnostic Tools for Monitoring Athletes’ Health Status Open
Acute or intense exercise is sometimes related to infections of the urinary tract. It can also lead to incorrect hydration as well as incorrect glomerular filtration due to the presence of high-molecular-weight proteins that cause damage t…
View article: Athlete’s Passport: Prevention of Infections, Inflammations, Injuries and Cardiovascular Diseases
Athlete’s Passport: Prevention of Infections, Inflammations, Injuries and Cardiovascular Diseases Open
Laboratory medicine in sports medicine is taking on an ever-greater role in the assessment and monitoring of an athlete’s health condition. The acute or intense exercise practiced by elite athletes can lead to the appearance of infections,…
View article: Methicillin-Resistant Staphylococcus aureus: Risk for General Infection and Endocarditis Among Athletes
Methicillin-Resistant Staphylococcus aureus: Risk for General Infection and Endocarditis Among Athletes Open
The first studies on Staphylococcus aureus (SA) infections in athletes were conducted in the 1980s, and examined athletes that perform in close physical contact, with particular attention to damaged or infected skin. Recent studies have us…
View article: HNP-1 and HBD-1 as Biomarkers for the Immune Systems of Elite Basketball Athletes
HNP-1 and HBD-1 as Biomarkers for the Immune Systems of Elite Basketball Athletes Open
Acute or strenuous exercise is sometimes related to upper respiratory tract infections in athletes. Practicing intense and regular exercise can lead to incorrect activation of the immune system, causing athletes to be excluded from trainin…
View article: Human Defensins: A Novel Approach in the Fight against Skin Colonizing Staphylococcus aureus
Human Defensins: A Novel Approach in the Fight against Skin Colonizing Staphylococcus aureus Open
Staphylococcus aureus is a microorganism capable of causing numerous diseases of the human skin. The incidence of S. aureus skin infections reflects the conflict between the host skin′s immune defenses and the S. aureus’ virulence elements…
View article: Sudden Cardiac Death in Young Athletes: Literature Review of Molecular Basis
Sudden Cardiac Death in Young Athletes: Literature Review of Molecular Basis Open
Intense athletic training and competition can rarely result in sudden cardiac death (SCD). Despite the introduction of pre-participation cardiovascular screening, especially among young competitive athletes, sport-related SCD remains a deb…