Oliver Cottrell
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View article: HES1 oscillations are required for cell cycle re-entry in oestrogen receptor positive breast cancer cells
HES1 oscillations are required for cell cycle re-entry in oestrogen receptor positive breast cancer cells Open
Long-term recurrence in breast cancer is driven by reactivation of dormant disseminated tumour cells (DTCs) and remains a major clinical challenge, particularly in oestrogen receptor positive (ER⁺) tumours. This process is underpinned by r…
View article: Identification of genes with oscillatory expression in glioblastoma – The paradigm of<i>SOX2</i>
Identification of genes with oscillatory expression in glioblastoma – The paradigm of<i>SOX2</i> Open
Quiescence, a reversible state of cell-cycle arrest, is an important state during both normal development and cancer progression. For example, in glioblastoma (GBM) quiescent glioblastoma stem cells (GSCs) play an important role in re-esta…