Oliver Redfern
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View article: Development and external validation of a clinical prediction model for new-onset atrial fibrillation in intensive care: a multicentre, retrospective cohort study
Development and external validation of a clinical prediction model for new-onset atrial fibrillation in intensive care: a multicentre, retrospective cohort study Open
National Institute for Health and Care Research (NIHR) and NIHR Oxford Biomedical Research Centre.
View article: Is age associated with different vital signs in adults presenting to hospital with bacterial infection? A systematic review and meta-analysis
Is age associated with different vital signs in adults presenting to hospital with bacterial infection? A systematic review and meta-analysis Open
Background It has long been suspected that the vital sign abnormalities that accompany bacterial infection are subtle or absent in older adults. This review summarises the evidence for whether older adults present with different vital sign…
View article: Oxygen therapy in early warning scores: a systematic review and meta-analysis
Oxygen therapy in early warning scores: a systematic review and meta-analysis Open
Background Early warning systems (EWS) used across the world typically assign a fixed number of points to patients receiving supplemental oxygen, regardless of amount. This ordinal binary approach may fail to recognise deteriorating patien…
View article: Why vital signs observations are delayed and interrupted on acute hospital wards: A multisite observational study
Why vital signs observations are delayed and interrupted on acute hospital wards: A multisite observational study Open
10863045, ISRCTN (6/8/2019).
View article: Perioperative risk scores: prediction, pitfalls, and progress
Perioperative risk scores: prediction, pitfalls, and progress Open
Purpose of review Perioperative risk scores aim to risk-stratify patients to guide their evaluation and management. Several scores are established in clinical practice, but often do not generalize well to new data and require ongoing updat…
View article: Nursing Team Composition and Mortality Following Acute Hospital Admission
Nursing Team Composition and Mortality Following Acute Hospital Admission Open
Importance Many studies show the adverse consequences of insufficient nurse staffing in hospitals, but safe and effective staffing is unlikely to be just about staff numbers. There are considerable areas of uncertainty, including whether t…
View article: COVID pandemic impact on hypertension management in North-East London: an observational cohort study using electronic health records
COVID pandemic impact on hypertension management in North-East London: an observational cohort study using electronic health records Open
Background The COVID19 pandemic had a major impact on primary care management of long-term conditions such as hypertension. This observational cohort study of adults with hypertension registered in 193 primary care practices in North-East …
View article: Inequities in hypertension management: observational cross-sectional study in North East London using electronic health records
Inequities in hypertension management: observational cross-sectional study in North East London using electronic health records Open
Background Hypertension is a key modifiable risk factor for cardiovascular disease – the leading cause of death in the UK. Good blood pressure (BP) control reduces mortality. However, health inequities may lead to variability in hypertensi…
View article: Opportunities to improve nutrition delivery in hospital after discharge from an intensive care unit: A mixed methods analysis
Opportunities to improve nutrition delivery in hospital after discharge from an intensive care unit: A mixed methods analysis Open
Background and Aims Though adequate nutrition following critical illness is fundamental to rehabilitation, it is poorly provided. To inform interventions to improve nutrition support for patients discharged from an intensive care unit (ICU…
View article: Inequities in hypertension management: an observational cross-sectional study in North-East London using electronic health records
Inequities in hypertension management: an observational cross-sectional study in North-East London using electronic health records Open
Background Hypertension is a key potentially modifiable risk factor for cardiovascular disease-the leading cause of death in the UK. Good blood pressure (BP) control reduces mortality; however, health inequalities may lead to variability i…
View article: Two-stage Detection of Murmurs from Phonocardiograms using Deep and One-class Methods
Two-stage Detection of Murmurs from Phonocardiograms using Deep and One-class Methods Open
Detection of heart murmurs from stethoscope sounds is a key clinical technique used to identify cardiac abnormalities.We describe the creation of an ensemble classifier using both deep and hand-crafted features to screen for heart murmurs …
View article: Contactless skin perfusion monitoring with video cameras: tracking pharmacological vasoconstriction and vasodilation using photoplethysmographic changes
Contactless skin perfusion monitoring with video cameras: tracking pharmacological vasoconstriction and vasodilation using photoplethysmographic changes Open
Objectives. Clinical assessment of skin perfusion informs prognosis in critically ill patients. Video camera monitoring could provide an objective, continuous method to monitor skin perfusion. In this prospective, interventional study of h…
View article: Protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patient
Protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patient Open
Introduction Most patients admitted to hospital recover with treatments that can be administered on the general ward. A small but important group deteriorate however and require augmented organ support in areas with increased nursing to pa…
View article: Outlier detection of vital sign trajectories from COVID-19 patients
Outlier detection of vital sign trajectories from COVID-19 patients Open
In this work, we present a novel trajectory comparison algorithm to identify abnormal vital sign trends, with the aim of improving recognition of deteriorating health. There is growing interest in continuous wearable vital sign sensors for…
View article: Evaluation of a digital system to predict unplanned admissions to the intensive care unit: A mixed-methods approach
Evaluation of a digital system to predict unplanned admissions to the intensive care unit: A mixed-methods approach Open
View article: How long do nursing staff take to measure and record patients’ vital signs observations in hospital? A time-and-motion study
How long do nursing staff take to measure and record patients’ vital signs observations in hospital? A time-and-motion study Open
View article: Corrigendum to “Trajectories of vital signs in patients with COVID-19” [Resuscitation 156 (2020) 99–106]
Corrigendum to “Trajectories of vital signs in patients with COVID-19” [Resuscitation 156 (2020) 99–106] Open
View article: Reply to: Trajectories of vital signs in patients with Covid-19
Reply to: Trajectories of vital signs in patients with Covid-19 Open
View article: How long do nursing staff take to measure and record patients’ vital signs observations in hospital? A time-and-motion study
How long do nursing staff take to measure and record patients’ vital signs observations in hospital? A time-and-motion study Open
Introduction Monitoring vital signs in hospital is an important part of safe patient care. However, there are no robust estimates of the workload it generates for nursing staff. This makes it difficult to plan adequate staffing to ensure c…
View article: Trajectories of vital signs in patients with COVID-19
Trajectories of vital signs in patients with COVID-19 Open
Patients with COVID-19 who deteriorate in hospital experience rapidly-worsening respiratory failure, with low SpO2 and high FiO2, but only minor abnormalities in other vital signs. This has potential implications for …
View article: Managing new-onset atrial fibrillation in critically ill patients: a systematic narrative review
Managing new-onset atrial fibrillation in critically ill patients: a systematic narrative review Open
Objectives The aim of this review is to summarise the latest evidence on efficacy and safety of treatments for new-onset atrial fibrillation (NOAF) in critical illness. Participants Critically ill adult patients who developed NOAF during a…
View article: The association between nurse staffing levels and a failure to respond to patients with deranged physiology: A retrospective observational study in the UK
The association between nurse staffing levels and a failure to respond to patients with deranged physiology: A retrospective observational study in the UK Open
View article: Uncertainty-Aware Model for Reliable Prediction of Sepsis in the ICU
Uncertainty-Aware Model for Reliable Prediction of Sepsis in the ICU Open
Predicting the onset of sepsis from clinical data is challenging, as physiological and laboratory measurements are sampled at different frequencies and missing data are not randomly distributed.Our team ("CRASHers") propose a two-model app…
View article: The National Early Warning Score 2 (NEWS2)
The National Early Warning Score 2 (NEWS2) Open
View article: The effect of fractional inspired oxygen concentration on early warning score performance: A database analysis
The effect of fractional inspired oxygen concentration on early warning score performance: A database analysis Open
View article: Reply to: NEWS2 needs to be tested in prospective trials involving patients with confirmed hypercapnia
Reply to: NEWS2 needs to be tested in prospective trials involving patients with confirmed hypercapnia Open
View article: Sepsis in Non-ICU Patients: A Call for Guideline Reassessment - The authors reply.
Sepsis in Non-ICU Patients: A Call for Guideline Reassessment - The authors reply. Open
View article: Nurses’ 12-hour shifts and missed or delayed vital signs observations on hospital wards: retrospective observational study
Nurses’ 12-hour shifts and missed or delayed vital signs observations on hospital wards: retrospective observational study Open
Objectives 12-hour shifts worked by nurses on acute hospital wards have been associated with increased rates of missed care reported by nurses. This study aimed to measure the association between nurses working shifts of at least 12 hours …
View article: A comparison of the ability of the National Early Warning Score and the National Early Warning Score 2 to identify patients at risk of in-hospital mortality: A multi-centre database study
A comparison of the ability of the National Early Warning Score and the National Early Warning Score 2 to identify patients at risk of in-hospital mortality: A multi-centre database study Open
NEWS2 modifications to NEWS do not improve discrimination of adverse outcomes in patients with documented T2RF and decrease discrimination in patients at risk of T2RF. Further evaluation of the relationship between SpO2 values, …