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View article: Integrin-mediated inhibition of CCN1 attenuates angiogenesis and joint damage in experimental rheumatoid arthritis
Integrin-mediated inhibition of CCN1 attenuates angiogenesis and joint damage in experimental rheumatoid arthritis Open
Background: CCN1 is a matricellular protein with known proangiogenic and immunomodulatory properties. Its role in rheumatoid arthritis (RA) remains incompletely defined. We aimed to determine whether CCN1 acts as a biomarker of disease pro…
View article: OX40L blockade protects against inflammation-driven fibrosis
OX40L blockade protects against inflammation-driven fibrosis Open
Significance Fibrosis is a leading cause of death in industrialized countries. Until now, there has been no effective therapy to prevent or counteract the fibrotic process. This article describes the effect of the blockade of a late costim…