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View article: Manifestations rhumatologiques des syndromes myélodysplasiques
Manifestations rhumatologiques des syndromes myélodysplasiques Open
View article: Severe autoimmune hemolytic anemia in ICU: a place for emergency plasma exchange? A French multicenter retrospective study
Severe autoimmune hemolytic anemia in ICU: a place for emergency plasma exchange? A French multicenter retrospective study Open
In this large ICU cohort, severe AIHA was associated with high mortality, driven by organ failure rather than anemia severity. PlEx are associated with survival, suggesting its potential role as a bridge to immunosuppressive therapy in sel…
View article: Comparative efficacy and safety of anakinra and canakinumab in patients with <scp>VEXAS</scp> syndrome – an international multicenter study
Comparative efficacy and safety of anakinra and canakinumab in patients with <span>VEXAS</span> syndrome – an international multicenter study Open
Objectives The aim of this study was to compare differences in clinical response, drug survival, and adverse event rates between anakinra and canakinumab in VEXAS syndrome. Methods This multicenter international study includes VEXAS patien…
View article: POS0221 PROSPECTIVE FOLLOW UP OF 37 PREGNANCIES IN WOMEN RECEIVING IL1 INHIBITORS FOR SYSTEMIC AUTOINFLAMMATORY DISEASES: AN MULTICENTRIC FRENCH STUDY FROM THE GR2 COHORT
POS0221 PROSPECTIVE FOLLOW UP OF 37 PREGNANCIES IN WOMEN RECEIVING IL1 INHIBITORS FOR SYSTEMIC AUTOINFLAMMATORY DISEASES: AN MULTICENTRIC FRENCH STUDY FROM THE GR2 COHORT Open
View article: IgA vasculitis associated with chronic myelomonocytic leukemia
IgA vasculitis associated with chronic myelomonocytic leukemia Open
View article: Global frequency, diagnosis, and treatment of hereditary angioedema with normal C1 inhibitor
Global frequency, diagnosis, and treatment of hereditary angioedema with normal C1 inhibitor Open
HAE-nC1INH may be more prevalent than previously reported. Importantly, our findings revealed varying diagnostic and treatment approaches. Validated, accessible diagnostic biomarkers and clinical outcomes derived from rigorous clinical tri…
View article: Higher risk profile among patients with TET2-mutated giant cell arteritis: a cluster analysis
Higher risk profile among patients with TET2-mutated giant cell arteritis: a cluster analysis Open
Objective We aimed to assess the prevalence of clonal haematopoiesis (CH) in patients with giant cell arteritis (GCA) compared with controls and individuals with other autoimmune diseases (AIDs) and to identify high-risk clinical/genetic p…
View article: Angioedema due to Acquired C1-Inhibitor Deficiency Associated With Monoclonal Gammopathies of Undetermined Significance Characteristics of a French National Cohort
Angioedema due to Acquired C1-Inhibitor Deficiency Associated With Monoclonal Gammopathies of Undetermined Significance Characteristics of a French National Cohort Open
Complete remission of AAE-C1-INH is correlated to complete remission of the underlying hematological malignancy, as defined by an undetectable serum monoclonal immunoglobulin. In our MGUS-associated acquired angioedema cohort, we recorded …
View article: Characteristics and outcomes associated with CD2 and CD25 expression on bone marrow mast cells in patients with systemic mastocytosis
Characteristics and outcomes associated with CD2 and CD25 expression on bone marrow mast cells in patients with systemic mastocytosis Open
Not available.
View article: Prevalence estimation of a rare disease with the French National Rare Disease Registry: example of TNF receptor associated periodic syndrome (TRAPS)
Prevalence estimation of a rare disease with the French National Rare Disease Registry: example of TNF receptor associated periodic syndrome (TRAPS) Open
Background rare diseases (RD) have progressively emerged as public health priority in many countries. Epidemiology still presents obstacles and extracting data from public health system remains insufficient. In France, RD database set up i…
View article: Prevalence and association of placental lesions with obstetrical features and outcome: data from French prospective study
Prevalence and association of placental lesions with obstetrical features and outcome: data from French prospective study Open
The placenta analysis is important to understand the origin of adverse obstetrical outcome and the risk for subsequent pregnancy.
View article: Recurrent cervical swelling syndrome as a rare cause of left supraclavicular edema: Case series and literature review
Recurrent cervical swelling syndrome as a rare cause of left supraclavicular edema: Case series and literature review Open
View article: Hydroxychloroquine in recurrent pregnancy loss: data from a French prospective multicenter registry
Hydroxychloroquine in recurrent pregnancy loss: data from a French prospective multicenter registry Open
STUDY QUESTION What are the outcomes of pregnancies exposed to hydroxychloroquine (HCQ) in women with a history of recurrent pregnancy loss (RPL), and what factors predict the course of these pregnancies beyond the first trimester? SUMMARY…
View article: Kidney involvement in myelodysplastic syndromes
Kidney involvement in myelodysplastic syndromes Open
Introduction The objective of this study was to describe kidney involvement in patients with myelodysplastic syndromes (MDS), their treatments, and outcomes. Methods We conducted a multicenter retrospective study in seven centers, identify…
View article: Hydroxychloroquine levels in pregnancy and materno-fetal outcomes in systemic lupus erythematosus patients
Hydroxychloroquine levels in pregnancy and materno-fetal outcomes in systemic lupus erythematosus patients Open
Objectives Data about hydroxychloroquine (HCQ) levels during pregnancy are sparse. We assessed HCQ whole-blood levels at first trimester of pregnancy as a potential predictor of maternal and obstetric/fetal outcomes in patients with system…
View article: Induction of regulatory T cells and efficacy of low-dose interleukin-2 in systemic sclerosis: interventional open-label phase 1–phase 2a study
Induction of regulatory T cells and efficacy of low-dose interleukin-2 in systemic sclerosis: interventional open-label phase 1–phase 2a study Open
Background Systemic sclerosis (SSc) is a chronic autoimmune disease, with impaired immune response, increased fibrosis and endothelial dysfunction. Regulatory T cells (Tregs), which are essential to control inflammation, tissue repair and …
View article: Assessment of the Tolerability and Effectiveness of Berotralstat for Long-term Prophylaxis in Hereditary Angioedema: Berolife Study Interim Analysis
Assessment of the Tolerability and Effectiveness of Berotralstat for Long-term Prophylaxis in Hereditary Angioedema: Berolife Study Interim Analysis Open
View article: Chronic Myelomonocytic Leukemia Patients With Lysozyme Nephropathy and Renal Infiltration Display Markers of Severe Disease
Chronic Myelomonocytic Leukemia Patients With Lysozyme Nephropathy and Renal Infiltration Display Markers of Severe Disease Open
International audience
View article: POS1513 IDENTIFYING HIGH-RISK PROFILE IN PRIMARY ANTIPHOSPHOLIPID SYNDROME THROUGH CLUSTER ANALYSIS: FRENCH MULTICENTRIC COHORT STUDY
POS1513 IDENTIFYING HIGH-RISK PROFILE IN PRIMARY ANTIPHOSPHOLIPID SYNDROME THROUGH CLUSTER ANALYSIS: FRENCH MULTICENTRIC COHORT STUDY Open
View article: POS0954 CLINICAL FEATURES AND GENOMIC LANDSCAPE OF MYELOPROLIFERATIVE NEOPLASM (MPN) PATIENTS WITH AUTOIMMUNE AND INFLAMMATORY DISEASES
POS0954 CLINICAL FEATURES AND GENOMIC LANDSCAPE OF MYELOPROLIFERATIVE NEOPLASM (MPN) PATIENTS WITH AUTOIMMUNE AND INFLAMMATORY DISEASES Open
View article: AB0844 ARTERIAL ISCHEMIC EVENTS AND VENOUS THROMBOSIS IN SYSTEMIC SCLEROSIS: DATA FROM A MONO-CENTRIC STUDY
AB0844 ARTERIAL ISCHEMIC EVENTS AND VENOUS THROMBOSIS IN SYSTEMIC SCLEROSIS: DATA FROM A MONO-CENTRIC STUDY Open
View article: #2664 CHRONIC MYELOMONOCYTIC LEUKEMIA (CMML) PATIENTS WITH LYSOZYME NEPHROPATHY AND CMML RENAL INFILTRATION DISPLAY MARKERS OF SEVERE DISEASE
#2664 CHRONIC MYELOMONOCYTIC LEUKEMIA (CMML) PATIENTS WITH LYSOZYME NEPHROPATHY AND CMML RENAL INFILTRATION DISPLAY MARKERS OF SEVERE DISEASE Open
Background and Aims Chronic myelomonocytic leukemia (CMML) is a hematologic disorder which is an overlap syndrome between myelodysplastic syndromes, and myeloproliferative neoplasms, and can be associated with autoimmune and inflammatory d…
View article: AB0582 DESCRIPTION OF ASYMPTOMATIC ANTI-PHOSPHOLIPID CARRIERS IN A FRENCH MULTICENTER COHORT STUDY
AB0582 DESCRIPTION OF ASYMPTOMATIC ANTI-PHOSPHOLIPID CARRIERS IN A FRENCH MULTICENTER COHORT STUDY Open
View article: Intravenous versus subcutaneous tocilizumab in Takayasu arteritis: multicentre retrospective study
Intravenous versus subcutaneous tocilizumab in Takayasu arteritis: multicentre retrospective study Open
Objectives In this large multicentre study, we compared the effectiveness and safety of tocilizumab intravenous versus subcutaneous (SC) in 109 Takayasu arteritis (TAK) patients. Methods We conducted a retrospective multicentre study in re…
View article: #2663 KIDNEY INVOLVEMENT IN MYELODYSPLASTIC SYNDROMES
#2663 KIDNEY INVOLVEMENT IN MYELODYSPLASTIC SYNDROMES Open
Background and Aims Myelodysplastic syndromes (MDS) are hematologic disorders characterized by ineffective and dysplastic hematopoiesis that can be associated with systemic inflammatory and autoimmune diseases. The objective of this study …
View article: AB0588 ADALIMUMAB FOR IMMUNE RELATED INFERTILITY: EFFICACY AND SAFETY FROM PROSPECTIVE FRENCH MULTICENTER REGISTRY
AB0588 ADALIMUMAB FOR IMMUNE RELATED INFERTILITY: EFFICACY AND SAFETY FROM PROSPECTIVE FRENCH MULTICENTER REGISTRY Open
Background Recurrent miscarriage (RM) is a frequent condition affecting about 1–3 % of couples and is one of the most frustrating and difficult areas in reproductive medicine since the etiology is often unknown and evidence-based diagnosis…
View article: French practical guidelines for the diagnosis and management of relapsing polychondritis
French practical guidelines for the diagnosis and management of relapsing polychondritis Open
Relapsing polychondritis is a rare systemic disease. It usually begins in middle-aged individuals. This diagnosis is mainly suggested in the presence of chondritis, i.e. inflammatory flares on the cartilage, in particular of the ears, nose…
View article: Identifying high-risk profile in primary antiphospholipid syndrome through cluster analysis: French multicentric cohort study
Identifying high-risk profile in primary antiphospholipid syndrome through cluster analysis: French multicentric cohort study Open
Introduction Antiphospholipid syndrome (APS) is an autoimmune disease characterised by thrombosis (arterial, venous or small vessel) or obstetrical events and persistent antiphospholipid antibodies (aPL), according to the Sydney classifica…
View article: Triple positive profile in antiphospholipid syndrome: prognosis, relapse and management from a retrospective multicentre study
Triple positive profile in antiphospholipid syndrome: prognosis, relapse and management from a retrospective multicentre study Open
Objective Antiphospholipid syndrome (APS) is defined by the association of thromboembolic and/or obstetrical clinical manifestations and the presence of antiphospholipid antibodies. The objective of our study was to evaluate the impact of …
View article: Clinical Features and Genomic Landscape of Myeloproliferative Neoplasm (MPN) Patients with Autoimmune and Inflammatory Diseases (AID)
Clinical Features and Genomic Landscape of Myeloproliferative Neoplasm (MPN) Patients with Autoimmune and Inflammatory Diseases (AID) Open
There are few data regarding the association of autoimmune and inflammatory diseases (AID) with Philadelphia negative myeloproliferative neoplasms (MPN). In this retrospective study, we describe the prevalence, clinical and biological feat…