Olivier Lortholary
YOU?
Author Swipe
View article: Consecutive non-Aspergillus Fungal Invasive Infections in Chronic Granulomatous Disease: Data from the French National Reference Center for Primary ImmunoDeficiencies and literature review
Consecutive non-Aspergillus Fungal Invasive Infections in Chronic Granulomatous Disease: Data from the French National Reference Center for Primary ImmunoDeficiencies and literature review Open
View article: Recent Systemic Antifungal Exposure and Nonsusceptible <i>Candida</i> in Hospitalized Patients, South Africa, 2012–2017
Recent Systemic Antifungal Exposure and Nonsusceptible <i>Candida</i> in Hospitalized Patients, South Africa, 2012–2017 Open
Candida bloodstream infections, and their increasing antifungal resistance, are a global concern. In this cross-sectional study, we analyzed 2,443 culture-confirmed candidemia cases reported in South Africa during 2012-2017 to assess the e…
View article: Diagnosis, management and the burden of symptoms of mastocytosis from the physician's perspective: A nationwide study
Diagnosis, management and the burden of symptoms of mastocytosis from the physician's perspective: A nationwide study Open
Summary Mastocytosis is categorized into cutaneous mastocytosis (CM), mast cell sarcoma and systemic mastocytosis (SM). Within SM, indolent SM (ISM) is the more frequent subtype. Adult patients with CM but without an extracutaneous biopsy …
View article: Travel Practices and Associated Risks in Adult Thoracic Transplant Recipients: A Monocentric Survey
Travel Practices and Associated Risks in Adult Thoracic Transplant Recipients: A Monocentric Survey Open
Background Little is known regarding the travel practices of thoracic organ transplant recipients and their potential associated morbidity. Methods A questionnaire was distributed to thoracic organ transplant recipients to capture demograp…
View article: Personalised risk-prediction tools for cryptococcal meningitis mortality to guide treatment stratification in sub-Saharan Africa: a prognostic modelling study based on pooled analysis of two randomised controlled trials
Personalised risk-prediction tools for cryptococcal meningitis mortality to guide treatment stratification in sub-Saharan Africa: a prognostic modelling study based on pooled analysis of two randomised controlled trials Open
National Institute for Health Research.
View article: Duration of systemic antifungal therapy for patients with invasive fungal diseases: A reassessment
Duration of systemic antifungal therapy for patients with invasive fungal diseases: A reassessment Open
Invasive fungal diseases are associated with significant morbidity and mortality, especially among immunocompromised patients, and often prompt for rapid and aggressive treatment aiming cure. Due to the expanding magnitude of patients burd…
View article: Causes of HIV-related CNS infection in Cameroon, Malawi, and Tanzania: epidemiological findings from the DREAMM HIV-related CNS implementation study
Causes of HIV-related CNS infection in Cameroon, Malawi, and Tanzania: epidemiological findings from the DREAMM HIV-related CNS implementation study Open
For the French and Portuguese translations of the abstract see Supplementary Materials section.
View article: Recent Antiretroviral Therapy Initiation Is Associated With Increased Mortality Risk in Human Immunodeficiency Virus–associated Cryptococcal Meningitis: An Analysis of Clinical Trial Data From Africa
Recent Antiretroviral Therapy Initiation Is Associated With Increased Mortality Risk in Human Immunodeficiency Virus–associated Cryptococcal Meningitis: An Analysis of Clinical Trial Data From Africa Open
Mortality from cryptococcal meningitis was higher in recent ART initiators. ART interruption in this group may lead to improved outcomes.
View article: Effectiveness, Safety, and Patterns of Real-World Isavuconazole Use in Europe (2015–2019)
Effectiveness, Safety, and Patterns of Real-World Isavuconazole Use in Europe (2015–2019) Open
This study adds to the growing body of evidence that whether used as first-line therapy or after the failure of other antifungal therapies, isavuconazole appears to have a promising clinical response and a good safety profile as an antifun…
View article: Reappraising Cladophialophora bantiana phaeohyphomycosis in France: retrospective nation-based study
Reappraising Cladophialophora bantiana phaeohyphomycosis in France: retrospective nation-based study Open
Santé Publique France.
View article: Comparison of prognostic scores according to <scp>WHO</scp> classification in 170 patients with advanced mastocytosis and C‐finding treated with midostaurin
Comparison of prognostic scores according to <span>WHO</span> classification in 170 patients with advanced mastocytosis and C‐finding treated with midostaurin Open
Advanced systemic mastocytosis (AdvSM) encompasses heterogeneous mastocytosis subtypes and is associated with poor outcomes. Although midostaurin was the first tyrosine kinase inhibitor to be approved for AdvSM patients, long‐lasting respo…
View article: Characteristics and outcomes associated with CD2 and CD25 expression on bone marrow mast cells in patients with systemic mastocytosis
Characteristics and outcomes associated with CD2 and CD25 expression on bone marrow mast cells in patients with systemic mastocytosis Open
Not available.
View article: Epidemiology and prognostic factors of mucormycosis in France (2012–2022): a cross-sectional study nested in a prospective surveillance programme
Epidemiology and prognostic factors of mucormycosis in France (2012–2022): a cross-sectional study nested in a prospective surveillance programme Open
View article: Cryptococcosis Associated With Biologic Therapy: A Narrative Review
Cryptococcosis Associated With Biologic Therapy: A Narrative Review Open
Cryptococcus is an opportunistic fungal pathogen that can cause disseminated infection with predominant central nervous system involvement in patients with compromised immunity. Biologics are increasingly used in the treatment of neoplasms…
View article: Formulation and Stability of a 1% Clarithromycin-Based Topical Skin Cream: A New Option to Treat Buruli Ulcers?
Formulation and Stability of a 1% Clarithromycin-Based Topical Skin Cream: A New Option to Treat Buruli Ulcers? Open
There are more than 170 known species of non-tuberculous mycobacteria, and some are responsible for serious diseases in people infected with them. One of these is Buruli ulcers, a neglected tropical disease endemic in more than 33 countrie…
View article: Deciphering Unexpected Vascular Locations of <i>Scedosporium</i> spp. and <i>Lomentospora prolificans</i> Fungal Infections, France
Deciphering Unexpected Vascular Locations of <i>Scedosporium</i> spp. and <i>Lomentospora prolificans</i> Fungal Infections, France Open
Scedosporium spp. and Lomentospora prolificans are emerging non-Aspergillus filamentous fungi. The Scedosporiosis/lomentosporiosis Observational Study we previously conducted reported frequent fungal vascular involvement, including aortiti…
View article: Uncovering the Unseen: Bordetella hinzii Emerges in a Lung Transplant Recipient
Uncovering the Unseen: Bordetella hinzii Emerges in a Lung Transplant Recipient Open
Bordetella hinzii (B. hinzii), a Gram-negative bacillus commonly associated with respiratory infections in animals, has garnered attention for its sporadic cases in humans, particularly in immunocompromised individuals. Despite its opportu…
View article: Risk factors for Nocardia infection among allogeneic hematopoietic cell transplant recipients: A case-control study of the Infectious Diseases Working Party of the European Society for Blood and Marrow Transplantation
Risk factors for Nocardia infection among allogeneic hematopoietic cell transplant recipients: A case-control study of the Infectious Diseases Working Party of the European Society for Blood and Marrow Transplantation Open
View article: Histological characterization of liver involvement in systemic mastocytosis
Histological characterization of liver involvement in systemic mastocytosis Open
Background and Aims Systemic mastocytosis (SM) is characterized by the accumulation of atypical mast cells (MCs) in organs. Liver histology of SM has been marginally described and accurate histological classification is critical, given the…
View article: Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM
Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM Open
View article: Development and validation of quantitative PCR assays for HIV-associated cryptococcal meningitis in sub-Saharan Africa: a diagnostic accuracy study
Development and validation of quantitative PCR assays for HIV-associated cryptococcal meningitis in sub-Saharan Africa: a diagnostic accuracy study Open
European and Developing Countries Clinical Trials Partnership; Swedish International Development Cooperation Agency; Wellcome Trust/UK Medical Research Council/UKAID Joint Global Health Trials; and UK National Institute for Health Research.
View article: Increased Risk of Invasive Aspergillosis in Immunocompromised Patients With Persistent SARS-CoV-2 Viral Shedding &gt;8 Weeks, Retrospective Case-control Study
Increased Risk of Invasive Aspergillosis in Immunocompromised Patients With Persistent SARS-CoV-2 Viral Shedding >8 Weeks, Retrospective Case-control Study Open
Background Immunocompromised patients now represent the population most at risk for severe coronavirus disease 2019. Persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral shedding was reported in these patients rang…
View article: The Evolution and Determinants of Mucormycosis Prognosis and Epidemiology in France: A Ten-Year Prospective Multicenter Study
The Evolution and Determinants of Mucormycosis Prognosis and Epidemiology in France: A Ten-Year Prospective Multicenter Study Open
View article: Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM
Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM Open
View article: Cladophialophora Bantiana &nbsp;Phaeohyphomycosis in France:&nbsp;A Reappraisal of Epidemiology, Therapeutic Strategy, and Outcome
Cladophialophora Bantiana Phaeohyphomycosis in France: A Reappraisal of Epidemiology, Therapeutic Strategy, and Outcome Open
View article: Characterization of Patients with Clonal Mast Cells in the Bone Marrow with Clinical Significance Not Otherwise Specified
Characterization of Patients with Clonal Mast Cells in the Bone Marrow with Clinical Significance Not Otherwise Specified Open
View article: <i>Cryptococcus neoformans</i> Infections Differ Among Human Immunodeficiency Virus (HIV)–Seropositive and HIV-Seronegative Individuals: Results From a Nationwide Surveillance Program in France
<i>Cryptococcus neoformans</i> Infections Differ Among Human Immunodeficiency Virus (HIV)–Seropositive and HIV-Seronegative Individuals: Results From a Nationwide Surveillance Program in France Open
Among 1107 cryptococcosis cases from the French surveillance network (2005–2020), the proportion of HIV-seronegative individuals has recently surpassed that of HIV-seropositive individuals. We observed marked differences in patient charact…
View article: Performance of clinical metagenomics in France: a prospective observational study
Performance of clinical metagenomics in France: a prospective observational study Open
For the French translation of the abstract see Supplementary Materials section.
View article: Genetic diversity and microevolution in clinical <i>Cryptococcus</i> isolates from Cameroon
Genetic diversity and microevolution in clinical <i>Cryptococcus</i> isolates from Cameroon Open
Cryptococcal meningitis is the second most common cause of death in people living with HIV/AIDS, yet we have a limited understanding of how cryptococcal isolates change over the course of infection. Cryptococcal infections are environmenta…
View article: New Approaches to Manage Infections in Transplant Recipients: Report From the 2023 GTI (Infection and Transplantation Group) Annual Meeting
New Approaches to Manage Infections in Transplant Recipients: Report From the 2023 GTI (Infection and Transplantation Group) Annual Meeting Open
International audience