Olof Dahlqvist Leinhard
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View article: Adverse Muscle Composition Is an Early Feature of CKD and Associates With Poor Function and Comorbidities
Adverse Muscle Composition Is an Early Feature of CKD and Associates With Poor Function and Comorbidities Open
View article: Evaluating the prevalence and severity of metabolic dysfunction‐associated steatotic liver disease in patients with type 2 diabetes mellitus in primary care
Evaluating the prevalence and severity of metabolic dysfunction‐associated steatotic liver disease in patients with type 2 diabetes mellitus in primary care Open
Background and aims The prevalence of metabolic dysfunction‐associated steatotic liver disease (MASLD) has increased during the epidemic of obesity. Type 2 diabetes mellitus (T2DM) is associated with progressive MASLD. Therefore, many guid…
View article: Quantifying Leg Muscle Disuse Atrophy During Bed Rest Using DXA, CT, and MRI
Quantifying Leg Muscle Disuse Atrophy During Bed Rest Using DXA, CT, and MRI Open
This study evaluated whether dual‐energy X‐ray absorptiometry (DXA), computed tomography (CT), and magnetic resonance imaging (MRI) provide comparable outcomes in quantifying disuse‐induced skeletal muscle atrophy. Although the calculation…
View article: Relationship Between Quantitative Magnetic Resonance Imaging Measures and Functional Changes in Patients With Duchenne Muscular Dystrophy
Relationship Between Quantitative Magnetic Resonance Imaging Measures and Functional Changes in Patients With Duchenne Muscular Dystrophy Open
Introduction/Aims Improved methodologies to monitor the progression of Duchenne muscular dystrophy (DMD) are needed, especially in the context of clinical trials. We report changes in muscle magnetic resonance imaging (MRI) parameters in p…
View article: ADVERSE MUSCLE COMPOSITION IS LINKED TO LOWER MITOCHONDRIAL RESPIRATION AND SLOWER WALKING SPEED
ADVERSE MUSCLE COMPOSITION IS LINKED TO LOWER MITOCHONDRIAL RESPIRATION AND SLOWER WALKING SPEED Open
Low muscle mass and fat infiltration are core features of sarcopenic obesity. We examined skeletal muscle mitochondrial respiration and walking speed in older adults with normal muscle composition (NMC), only low muscle volume (LMV), only …
View article: Longitudinal changes in regional fat and muscle composition and cardiometabolic biomarkers over 5 years of hormone therapy in transgender individuals
Longitudinal changes in regional fat and muscle composition and cardiometabolic biomarkers over 5 years of hormone therapy in transgender individuals Open
Background Longitudinal studies investigating hormone therapy in transgender individuals are rare and often limited to 1‐ to 2‐year follow‐up periods. Objectives and Methods We examined changes in body composition, muscle volumes, and fat …
View article: Body composition and muscle composition phenotypes in patients on waitlist and shortly after liver transplant – results from a pilot study
Body composition and muscle composition phenotypes in patients on waitlist and shortly after liver transplant – results from a pilot study Open
View article: #1458 Adverse muscle composition predicts all-cause mortality in CKD
#1458 Adverse muscle composition predicts all-cause mortality in CKD Open
Background and Aims Sarcopenia is common in CKD and associates with morbidity and mortality. A rapid and standardized MRI (Magnetic Resonance Imaging) scan protocol allows an accurate muscle composition analysis by quantification of skelet…
View article: Dissecting unique and common variance across body and brain health indicators using age prediction
Dissecting unique and common variance across body and brain health indicators using age prediction Open
Ageing is a heterogeneous multisystem process involving different rates of decline in physiological integrity across biological systems. The current study dissects the unique and common variance across body and brain health indicators and …
View article: Effect of liraglutide on thigh muscle fat and muscle composition in adults with overweight or obesity: Results from a randomized clinical trial
Effect of liraglutide on thigh muscle fat and muscle composition in adults with overweight or obesity: Results from a randomized clinical trial Open
Background Excess muscle fat is observed in obesity and associated with greater burden of cardiovascular risk factors and higher risk of mortality. Liraglutide reduces total body weight and visceral fat but its effect on muscle fat and adv…
View article: Effect of tirzepatide on body fat distribution pattern in people with type 2 diabetes
Effect of tirzepatide on body fat distribution pattern in people with type 2 diabetes Open
Aims To describe the overall fat distribution patterns independent of body mass index (BMI) in participants with type 2 diabetes (T2D) in the SURPASS‐3 MRI substudy by comparison with sex‐ and BMI‐matched virtual control groups (VCGs) deri…
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Contents Open
View article: Risk stratification using magnetic resonance imaging-derived, personalized z-scores of visceral adipose tissue, subcutaneous adipose tissue, and liver fat in persons with obesity
Risk stratification using magnetic resonance imaging-derived, personalized z-scores of visceral adipose tissue, subcutaneous adipose tissue, and liver fat in persons with obesity Open
Personalized MR-derived fat z-scores can identify phenotypes of obesity with specific cardiometabolic risk profiles regardless of BMI. Current guidelines for bariatric surgery based on BMI exclude some of these high-risk patients.
View article: Pain and the biochemistry of fibromyalgia: patterns of peripheral cytokines and chemokines contribute to the differentiation between fibromyalgia and controls and are associated with pain, fat infiltration and content
Pain and the biochemistry of fibromyalgia: patterns of peripheral cytokines and chemokines contribute to the differentiation between fibromyalgia and controls and are associated with pain, fat infiltration and content Open
Objectives This explorative study analyses interrelationships between peripheral compounds in saliva, plasma, and muscles together with body composition variables in healthy subjects and in fibromyalgia patients (FM). There is a need to be…
View article: A rapid, non-invasive, clinical surveillance for CachExia, sarcopenia, portal hypertension, and hepatocellular carcinoma in end-stage liver disease: the ACCESS-ESLD study protocol
A rapid, non-invasive, clinical surveillance for CachExia, sarcopenia, portal hypertension, and hepatocellular carcinoma in end-stage liver disease: the ACCESS-ESLD study protocol Open
Background Liver cirrhosis, the advanced stage of many chronic liver diseases, is associated with escalated risks of liver-related complications like decompensation and hepatocellular carcinoma (HCC). Morbidity and mortality in cirrhosis p…
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Contents Open
View article: Dissecting unique and common variance across body and brain health indicators using age prediction
Dissecting unique and common variance across body and brain health indicators using age prediction Open
Ageing is a heterogeneous multisystem process involving different rates of decline in physiological integrity across biological systems. The current study dissects the unique and common variance across body and brain health indicators and …
View article: Skewness in Body fat Distribution Pattern Links to Specific Cardiometabolic Disease Risk Profiles
Skewness in Body fat Distribution Pattern Links to Specific Cardiometabolic Disease Risk Profiles Open
Objective Fat distribution pattern could help determine cardiometabolic risk profile. This study aimed to evaluate the association of balance/imbalance between visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue (aSAT), an…
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Contents Open
View article: #3296 ADVERSE MUSCLE COMPOSITION ASSESSED BY MRI ASSOCIATES TO POOR FUNCTIONAL PERFORMANCE AND METABOLIC COMORBIDITIES IN CKD
#3296 ADVERSE MUSCLE COMPOSITION ASSESSED BY MRI ASSOCIATES TO POOR FUNCTIONAL PERFORMANCE AND METABOLIC COMORBIDITIES IN CKD Open
Background and Aims CKD is associated with alterations in body composition, such as reduced muscle mass, increased amount of fat or both simultaneously. Furthermore, both sarcopenia and sarcopenic obesity are associated with worse physical…
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Contents Open
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Contents Open
View article: Fatty infiltrate and neck muscle volume in individuals with chronic whiplash associated disorders compared to healthy controls – a cross sectional case–control study
Fatty infiltrate and neck muscle volume in individuals with chronic whiplash associated disorders compared to healthy controls – a cross sectional case–control study Open
View article: Fat infiltration in the thigh muscles is associated with symptomatic spinal stenosis and reduced physical functioning in adults with achondroplasia
Fat infiltration in the thigh muscles is associated with symptomatic spinal stenosis and reduced physical functioning in adults with achondroplasia Open
View article: Adverse muscle composition is a significant risk factor for all-cause mortality in NAFLD
Adverse muscle composition is a significant risk factor for all-cause mortality in NAFLD Open
View article: The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition Open
View article: 265th ENMC International Workshop: Muscle imaging in Facioscapulohumeral Muscular Dystrophy (FSHD): relevance for clinical trials. 22–24 April 2022, Hoofddorp, The Netherlands
265th ENMC International Workshop: Muscle imaging in Facioscapulohumeral Muscular Dystrophy (FSHD): relevance for clinical trials. 22–24 April 2022, Hoofddorp, The Netherlands Open
View article: Liver, visceral and subcutaneous fat in men and women of South Asian and white European descent: a systematic review and meta-analysis of new and published data
Liver, visceral and subcutaneous fat in men and women of South Asian and white European descent: a systematic review and meta-analysis of new and published data Open
Aims/hypothesis South Asians have a two- to fivefold higher risk of developing type 2 diabetes than those of white European descent. Greater central adiposity and storage of fat in deeper or ectopic depots are potential contributing mechan…
View article: Fibromyalgia in women: association of inflammatory plasma proteins, muscle blood flow, and metabolism with body mass index and pain characteristics
Fibromyalgia in women: association of inflammatory plasma proteins, muscle blood flow, and metabolism with body mass index and pain characteristics Open
Introduction: Obesity is a common comorbidity in fibromyalgia (FM). Both FM and obesity have been connected to low-grade inflammation, although it is possible that previously reported inflammatory alterations in FM primarily may be linked …
View article: Morphology and composition of the ventral neck muscles in individuals with chronic whiplash related disorders compared to matched healthy controls: a cross-sectional case–control study
Morphology and composition of the ventral neck muscles in individuals with chronic whiplash related disorders compared to matched healthy controls: a cross-sectional case–control study Open