Omar Abdel‐Rahman
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View article: Les avancées dans le traitement du cancer nécessitent des changements de toute urgence dans les effectifs en oncologie
Les avancées dans le traitement du cancer nécessitent des changements de toute urgence dans les effectifs en oncologie Open
View article: The impact of peri-operative chemotherapy on the Outcomes of Patients with non-metastatic biliary tract cancer
The impact of peri-operative chemotherapy on the Outcomes of Patients with non-metastatic biliary tract cancer Open
Introduction Biliary-tract cancers, including intra- and extra-hepatic cholangiocarcinoma and gallbladder carcinoma, are uncommon but highly lethal. They represent roughly 2–3 % of new cancer diagnoses yet contribute about 5 % of cancer-re…
View article: Advances in cancer therapy require urgent changes to the oncology workforce
Advances in cancer therapy require urgent changes to the oncology workforce Open
View article: Thermal performance evaluation of phase changing materials in double glazing units for office buildings in Egypt
Thermal performance evaluation of phase changing materials in double glazing units for office buildings in Egypt Open
View article: Correction: Consensus Statement: Recommendations on Actionable Biomarker Testing for Thyroid Cancer Management
Correction: Consensus Statement: Recommendations on Actionable Biomarker Testing for Thyroid Cancer Management Open
View article: Consensus Statement: Recommendations on Actionable Biomarker Testing for Thyroid Cancer Management
Consensus Statement: Recommendations on Actionable Biomarker Testing for Thyroid Cancer Management Open
View article: Multidisciplinary Canadian consensus on the multimodal management of high-risk and radioactive iodine-refractory thyroid carcinoma
Multidisciplinary Canadian consensus on the multimodal management of high-risk and radioactive iodine-refractory thyroid carcinoma Open
Most follicular cell-derived differentiated thyroid carcinomas are regarded as low-risk neoplasms prompting conservative therapeutic management. Here, we provide consensus recommendations reached by a multidisciplinary group of endocrinolo…
View article: Remission of Ectopic Cushing Syndrome Secondary to Medullary Thyroid Cancer With Vandetanib and Selpercatinib
Remission of Ectopic Cushing Syndrome Secondary to Medullary Thyroid Cancer With Vandetanib and Selpercatinib Open
Medullary thyroid cancer (MTC) is a neuroendocrine tumor associated with activating mutations of the rearranged during transfection (RET) proto-oncogene. These tumors may rarely secrete adrenocorticotropin or corticotropin-releasing hormon…
View article: Supplementary material: Prognostic and predictive value of microsatellite instability status among patients with colorectal cancer
Supplementary material: Prognostic and predictive value of microsatellite instability status among patients with colorectal cancer Open
This is a peer-reviewed supplementary table for the article 'Prognostic and predictive value of microsatellite instability status among patients with colorectal cancer' published in the Journal of Comparative Eff…
View article: Increasing access to palliative care for patients with advanced cancer of African and Latin American descent: a patient-oriented community-based study protocol
Increasing access to palliative care for patients with advanced cancer of African and Latin American descent: a patient-oriented community-based study protocol Open
Background Cancer disparities are a major public health concern in Canada, affecting racialized communities of Latin American and African descent, among others. This is evident in lower screening rates, lower access to curative, and pallia…
View article: Switch to generic formulation of temozolomide results in statistically significant increase in grade 3 and 4 bone marrow toxicity in glioma patients in the province of Alberta
Switch to generic formulation of temozolomide results in statistically significant increase in grade 3 and 4 bone marrow toxicity in glioma patients in the province of Alberta Open
Background Temozolomide (TMZ) is an oral, systemic chemotherapy used chiefly for treating high-grade glioma. Due to the rising costs of systemic chemotherapy, many jurisdictions have replaced brand name with generic formulations. The aim o…
View article: Clarifying the role of adjuvant therapy after multi-agent neoadjuvant chemotherapy for patients with pancreatic ductal adenocarcinoma
Clarifying the role of adjuvant therapy after multi-agent neoadjuvant chemotherapy for patients with pancreatic ductal adenocarcinoma Open
View article: P-17 Impacts of patient-reported non-hormonal symptoms on outcomes of patients with neuroendocrine neoplasms (NENs)
P-17 Impacts of patient-reported non-hormonal symptoms on outcomes of patients with neuroendocrine neoplasms (NENs) Open
View article: Challenges in Diagnosis and Treatment of Pancreatic Exocrine Insufficiency among Patients with Pancreatic Ductal Adenocarcinoma
Challenges in Diagnosis and Treatment of Pancreatic Exocrine Insufficiency among Patients with Pancreatic Ductal Adenocarcinoma Open
Pancreatic ductal adenocarcinoma (PDAC) is the most common malignancy of the pancreas and is associated with an extremely poor prognosis. Many PDAC patients suffer from profound nutritional complications such as nutrient deficiencies, weig…
View article: Impact of Patient Characteristics on the Outcomes of Patients with Gastrointestinal Cancers Treated with Immune Checkpoint Inhibitors
Impact of Patient Characteristics on the Outcomes of Patients with Gastrointestinal Cancers Treated with Immune Checkpoint Inhibitors Open
Gastrointestinal (GI) cancers are a group of malignancies that globally account for a significant portion of cancer incidence and cancer-related death. Survival outcomes for esophageal, gastric, pancreatic, and hepatobiliary cancers remain…
View article: Borderline Resectable Pancreatic Cancer: Challenges for Clinical Management
Borderline Resectable Pancreatic Cancer: Challenges for Clinical Management Open
Though progress has been made, the optimal management of BR-PDAC is uncertain. Phase III trials utilizing modern chemotherapeutic regimens are needed to establish a standard of care.
View article: Exploring the Relationship between Obesity, Metabolic Syndrome and Neuroendocrine Neoplasms
Exploring the Relationship between Obesity, Metabolic Syndrome and Neuroendocrine Neoplasms Open
Obesity is a major burden for modern medicine, with many links to negative health outcomes, including the increased incidence of certain cancer types. Interestingly, some studies have supported the concept of an “Obesity Paradox”, where so…
View article: Impact of perioperative chemotherapy on survival outcomes among patients with metastatic colorectal cancer to the liver
Impact of perioperative chemotherapy on survival outcomes among patients with metastatic colorectal cancer to the liver Open
Aim: Compare overall survival (OS) between adjuvant and neoadjuvant chemotherapy and analyze the effect of chemotherapy on OS. Materials & methods: National Cancer Database was queried for patients diagnosed with metastatic colorectal aden…
View article: Cancer Burden Among Arab-World Females in 2020: Working Toward Improving Outcomes
Cancer Burden Among Arab-World Females in 2020: Working Toward Improving Outcomes Open
PURPOSE Cancer is the leading cause of morbidity and mortality worldwide. This work presents the Arab-world females' cancers (AFCs) statistics in 2020, compared with the 2018 AFCs statistics, the Arab-world male cancers statistics, and the…
View article: The Role of Surgery in Small Differentiated Thyroid Cancer
The Role of Surgery in Small Differentiated Thyroid Cancer Open
Introduction The incidence of small, differentiated thyroid cancer (DTC) cases has been increasing in the United States and the world mainly due to incidental detection because of widespread use of diagnostic modalities. While the option …
View article: Managing 5FU Cardiotoxicity in Colorectal Cancer Treatment
Managing 5FU Cardiotoxicity in Colorectal Cancer Treatment Open
Matthew Anaka, Omar Abdel-Rahman Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, AB, CanadaCorrespondence: Omar Abdel-RahmanDepartment of Oncology, Cross Cancer Institute, University of Alberta, 11560 Unive…
View article: Factors associated with fatal coronavirus disease 2019 infections among cancer patients in the US FDA Adverse Event Reporting System database
Factors associated with fatal coronavirus disease 2019 infections among cancer patients in the US FDA Adverse Event Reporting System database Open
Aim: To explore factors affecting coronavirus disease 2019 (COVID-19) mortality among cancer patients based on a pharmacovigilance database. Methods: US FDA Adverse Event Reporting System (FAERS) quarterly data extract files …
View article: SO-21 Impact of timing of perioperative chemotherapy on survival outcomes among patients with colorectal liver metastases: A propensity score matching of the national cancer database
SO-21 Impact of timing of perioperative chemotherapy on survival outcomes among patients with colorectal liver metastases: A propensity score matching of the national cancer database Open
View article: What is the real value of metronomic chemotherapy in the treatment of gastrointestinal cancer?
What is the real value of metronomic chemotherapy in the treatment of gastrointestinal cancer? Open
Conventional chemotherapy (CT) is administered at maximum tolerated doses (MTDs) required to attain tumoristatic/tumoricidal effects. Unfortunately, it requires lengthy drug-free breaks due to myel...
View article: Impact of Perioperative Chemotherapy on Survival Outcomes Among Patients with Metastatic Colorectal Cancer to the Liver
Impact of Perioperative Chemotherapy on Survival Outcomes Among Patients with Metastatic Colorectal Cancer to the Liver Open
IntroductionWhile surgical resection for primary tumor and distant metastases is recommended among individuals with resectable colorectal liver metastases, the role and timing of perioperative systemic therapy is not yet defined.Materials …
View article: Hospitalizations among early-stage colon cancer patients receiving adjuvant chemotherapy: a real-world study
Hospitalizations among early-stage colon cancer patients receiving adjuvant chemotherapy: a real-world study Open
View article: Patterns of cost-related medication underuse among Canadian adults with cancer: a cross-sectional study using survey data
Patterns of cost-related medication underuse among Canadian adults with cancer: a cross-sectional study using survey data Open
The toll of CRMU among adults seems to be unequally carried by women, racial minorities, and younger (< 65 yr) and uninsured patients with cancer. Discussion about a national pharmacare program for people without private insurance is neede…
View article: Author response for "Outcomes of small‐cell versus large‐cell gastroenteropancreatic neuroendocrine carcinomas: A population‐based study"
Author response for "Outcomes of small‐cell versus large‐cell gastroenteropancreatic neuroendocrine carcinomas: A population‐based study" Open
View article: Patterns and Trends of Cancer Screening in Canada: Results From a Contemporary National Survey
Patterns and Trends of Cancer Screening in Canada: Results From a Contemporary National Survey Open
Background: The aim of this study was to assess the patterns and trends of colorectal, breast, and cervical cancer screening within a contemporary cohort of Canadian adults. Methods: Canadian Community Health Survey datasets (2007–2016) we…
View article: Socioeconomic disparities in the prevalence of comorbid chronic conditions among Canadian adults with cancer
Socioeconomic disparities in the prevalence of comorbid chronic conditions among Canadian adults with cancer Open
To evaluate the prevalence of comorbid chronic conditions among Canadian adults with cancer and the impact of socioeconomic background on the distribution of these conditions. Canadian Community Health Survey (CCHS) 2017–2018 dataset was a…