Explanipedia

Embolization of the middle meningeal artery for chronic subdural hematoma: The OTEMACS multicenter, randomized, clinical trial protocol Open

Sam Ng, Imad Derraz, Gaultier Marnat, Vincent Jecko, Jean Papaxanthos , et al. · 2025

Background The role of middle meningeal artery (MMA) embolization as an adjunct to standard treatment in chronic subdural hematoma (CSDH) is debated. Further randomized trials are needed to establish MMA embolization as an essential therap…

Contemporary Results of Mechanical Thrombectomy and Impact of First-Line Technique on Outcome: The INSPIRE-S Global Registry Open

Marc Rodrigo‐Gisbert, Marc Ribó, Markus Möhlenbruch, Sanjeev Nayak, Christophe Cognard , et al. · 2025

The primary results of real-world data from INSPIRE-S showed overall high rates of first-pass complete reperfusion and final clinical outcomes that were similar among the 3 MT techniques.

Balloon-Guide Catheters in Mechanical Thrombectomy: Current State of Knowledge and Perspectives Open

Gaultier Marnat, Romain Bourcier, Bertrand Lapergue, Raphaël Blanc, Fouzi Bala , et al. · 2025

Susceptibility Vessel Sign and Intravenous Alteplase in Stroke Patients Treated with Thrombectomy Open

Morin Beyeler, Roman Rohner, Petra Ijäs, Omer Eker, Christophe Cognard , et al. · 2025

Contrast quality control for segmentation task based on deep learning models—Application to stroke lesion in CT imaging Open

J. Moreau, Laura Mechtouff, David Rousseau, Omer Eker, Yves Berthezène , et al. · 2025

Introduction Although medical imaging plays a crucial role in stroke management, machine learning (ML) has been increasingly used in this field, particularly in lesion segmentation. Despite advances in acquisition technologies and segmenta…

Quantitative imaging outperforms No-reflow in predicting functional outcomes in a translational stroke model Open

Justine Debatisse, Lucie Chalet, Omer Eker, Tae‐Hee Cho, Guillaume Becker , et al. · 2025

Microvascular dysfunction and no-reflow are considered a major cause of secondary damage despite revascularization in acute ischemic stroke (AIS), ultimately affecting patient outcomes. We used quantitative PET-MRI imaging to characterize …

FRED-EPI study: Safety and efficacy of FRED/FRED Jr aneurysm treatment in current clinical practice Open

Laurent Pierot, Denis Herbreteau, Xavier Barreau, Hervé Brunel, Jacques Sédat , et al. · 2025

FRED-EPI confirms good safety of aneurysm treatment with FRED/FRED Jr in current clinical practice with 4.4% 1-year morbimortality.

Intérêt du Macaca fascicularis avec occlusion de l’artère cérébrale moyenne pour étudier la récupération fonctionnelle post-AVC ischémique : étude de cas Open

Julie Maulavé, Justine Debatisse, Océane Wateau, Omer Eker, Emmanuelle Canet‐Soulas , et al. · 2025

Cette étude de cas explore les changements précoces de la perfusion cérébrale après un accident vasculaire cérébral ischémique induit par occlusion de l’artère cérébrale moyenne dans un modèle primate non-humain, afin d'identifier des marq…

On the Derivation of a New One-Dimensional Model for Blood Flows and Its Numerical Approximation Open

Yolhan Mannes, Mehmet Ersoy, Omer Eker · 2025

Iatrogenic arterial vasospasm during mechanical thrombectomy requiring treatment with intra‐arterial nimodipine might be associated with worse outcomes Open

Serine Ferhat, Guillaume Bellanger, Małgorzata Milnerowicz, Maéva Kyheng, Julien Labreuche , et al. · 2024

Background and Purpose Vasospasm is a common iatrogenic event during mechanical thrombectomy (MT). In such circumstances, intra‐arterial nimodipine administration is occasionally considered. However, its use in the treatment of iatrogenic …

A NEW TWO-DIMENSIONAL BLOOD FLOW MODEL AND ITS RKDG APPROXIMATION Open

Mehmet Ersoy, Yolhan Mannes, Omer Eker · 2024

We propose a new two-dimensional blood flow reduced model taking into account of complex artery geometry as in the case of severe aneurysm. We derive the model from the three-dimensional Navier-Stokes equations written in a curvilinear co…

Time to Treatment With Intravenous Thrombolysis Before Thrombectomy and Functional Outcomes in Acute Ischemic Stroke Open

Johannes Kaesmacher, Fabiano Cavalcante, Manon Kappelhof, Kilian M. Treurniet, Leon A. Rinkel , et al. · 2024

Importance The benefit of intravenous thrombolysis (IVT) for acute ischemic stroke declines with longer time from symptom onset, but it is not known whether a similar time dependency exists for IVT followed by thrombectomy. Objective To de…

Impact of Day 1 carotid patency on outcome in dissection-related tandem occlusions treated with mechanical thrombectomy Open

Guillaume Perrin, Elisabeth Molinier, Benjamin Gory, Maéva Kyheng, Julien Labreuche , et al. · 2024

MRI vs CT for Baseline Imaging Evaluation in Acute Large Artery Ischemic Stroke Open

Joachim Fladt, Johannes Kaesmacher, Thomas R. Meinel, Lukas Bütikofer, Daniel Strbian , et al. · 2023

ClinicalTrials.gov Identifier: NCT03192332.

The PREMISE database of 20 Macaca fascicularis PET/MRI brain images available for research Open

Lucie Chalet, Justine Debatisse, Océane Wateau, Timothé Boutelier, Marlène Wiart , et al. · 2023

Author Correction: A simplified mesoscale 3D model for characterizing fibrinolysis under flow conditions Open

Rémy Petkantchin, Alexandre Rousseau, Omer Eker, Karim Zouaoui Boudjeltia, Franck Raynaud , et al. · 2023

Comment on Kilian et al. Comparing Characteristics and Treatment of Brain Vascular Malformations in Children and Adults with HHT. J. Clin. Med. 2023, 12, 2704 Open

Omer Eker, Sophie Dupuis‐Girod, Claire L. Shovlin, Edoardo Boccardi · 2023

We read with interest the recent article by Killian et al. regarding the characteristics and treatment of brain vascular malformations (VMs) in children and adults with hereditary hemorrhagic telangiectasia (HHT) [...]

Value of intravenous thrombolysis in endovascular treatment for large-vessel anterior circulation stroke: individual participant data meta-analysis of six randomised trials Open

Charles B.L.M. Majoie, Fabiano Cavalcante, Jan Gralla, Pengfei Yang, Johannes Kaesmacher , et al. · 2023

A simplified mesoscale 3D model for characterizing fibrinolysis under flow conditions Open

Rémy Petkantchin, Alexandre Rousseau, Omer Eker, Karim Zouaoui Boudjeltia, Franck Raynaud , et al. · 2023

One of the routine clinical treatments to eliminate ischemic stroke thrombi is injecting a biochemical product into the patient’s bloodstream, which breaks down the thrombi’s fibrin fibers: intravenous or intravascular thrombolysis. Howeve…

O14/141 FIRST, International Prospective Multicenter Study of Endovascular Treatment of Intracranial Aneurysms with SILK VISTA and SILK VISTA BABY: 1-year study results Open

Mario Martínez‐Galdámez, Omer Eker, Charbel Mounayer, José E. Cohen, Michel Piotin , et al. · 2023

Introduction Flow diverters (FD) are increasingly used, becoming an established treatment option for complex intracranial aneurysms. Delivered through a 0.017' microcatheter, the low-profile Silk Vista Baby FD (Balt Extrusion SAS, France) …

O02/16 COATING study (the first RCT evaluating a surface-modified flow diverter – p64-MW-HPC): current status Open

Laurent Pierot, Omer Eker, Laurent Spelle, Victoria Hellstern, Xavier Barreau , et al. · 2023

Introduction Flow diversion (FD) is increasingly used for the treatment of intracranial aneurysms due to its efficacy and performance. Initially limited to large and giant ICA aneurysms, the FD approach has progressively enlarged to distal…

Successful Thrombectomy Improves Functional Outcome in Tandem Occlusions with a Large Ischemic Core Open

Benjamin Gory, Stephanos Finitsis, Jean‐Philippe Désilles, Arturo Consoli, Mikaël Mazighi , et al. · 2023

O-056 Coating study (the first RCT evaluating a surface-modified flow diverter/P64-MW-HPC): current status Open

Laurent Pierot, Omer Eker, Laurent Spelle, Xavier Barreau, Victoria Hellstern , et al. · 2023

Introduction/Purpose The most recent development in the field of devices dedicated to aneurysm treatment is surface-modified flow diverters (FD). Surface modification has different roles including facilitating navigation, increasing endoth…

O-057 Instant study: a recent evaluation of coiling in aneurysm treatment Open

Laurent Pierot, Omer Eker, Jérôme Berge, Jean‐Christophe Gentric, O. Lévrier , et al. · 2023

Introduction/Purpose Despite the development of new technologies dedicated to the endovascular treatment of intracranial aneurysms (IA) like flow diversion or intrasaccular flow disruption, coiling is still the first-line endovascular trea…

Early Detection of Underlying Cavernomas in Patients with Spontaneous Acute Intracerebral Hematomas Open

Alexandre Bani‐Sadr, Omer Eker, Tae‐Hee Cho, Roxana Améli, Moncef Berhouma , et al. · 2023

An imaging model including ovoid/spherical shape, regular margins, absence of extralesional hemorrhage, and absence of peripheral rim enhancement accurately identifies cavernoma-related acute spontaneous cerebral hematomas in young patient…

A simplified mesoscale 3D model for characterizing fibrinolysis under flow conditions Open

Rémy Petkantchin, Alexandre Rousseau, Omer Eker, Karim Zouaoui Boudjeltia, Franck Raynaud , et al. · 2023

One of the routine clinical treatments to eliminate ischemic stroke thrombi is injecting a biochemical product into the patient’s bloodstream, which breaks down the thrombi’s fibrin fibers: intravenous or intravascular thrombolysis. Howeve…

A Novel Autoencoders-LSTM Model for Stroke Outcome Prediction Using Multimodal MRI Data Open

Nima Hatami, Laura Mechtouff, David Rousseau, Tae‐Hee Cho, Omer Eker , et al. · 2023

International audience

Difficulty Metrics Study for Curriculum-Based Deep Learning in the Context of Stroke Lesion Segmentation Open

J. Moreau, Laura Mechtouff, David Rousseau, Tae‐Hee Cho, Omer Eker , et al. · 2023

International audience

Spatio-Temporal Characterization of Brain Inflammation in a Non-human Primate Stroke Model Mimicking Endovascular Thrombectomy Open

Guillaume Becker, Justine Debatisse, M Riviere, Claire Crola Da Silva, Maude Beaudoin‐Gobert , et al. · 2023

A Novel Autoencoders-LSTM Model for Stroke Outcome Prediction using Multimodal MRI Data Open

Nima Hatami, Laura Mechtouff, David Rousseau, Tae‐Hee Cho, Omer Eker , et al. · 2023

Patient outcome prediction is critical in management of ischemic stroke. In this paper, a novel machine learning model is proposed for stroke outcome prediction using multimodal Magnetic Resonance Imaging (MRI). The proposed model consists…

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