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View article: Crosstalk between ferroptosis and miRNA in type 2 diabetes mellitus and possible therapeutic targeting
Crosstalk between ferroptosis and miRNA in type 2 diabetes mellitus and possible therapeutic targeting Open
Type 2 diabetes (T2D) accounts for over 90% of diabetes mellitus and is characterized by peripheral tissue insulin resistance, a defective compensatory insulin secretion, and reduced insulin output from pancreatic β -cells. T2D is a comple…
View article: Molecular identification and histopathological of Cysticercus tenuicollis infestation among small ruminants
Molecular identification and histopathological of Cysticercus tenuicollis infestation among small ruminants Open
Small ruminant infections by the Cysticercus tenuicollis result in financial losses because of the condemnation of infected organs, which can happen in unsanitary conditions and is regarded as an ecotoxicological risk factor. Therefore, a …
View article: The functional and molecular roles of p75 neurotrophin receptor (p75<sup>NTR</sup>) in epilepsy
The functional and molecular roles of p75 neurotrophin receptor (p75<sup>NTR</sup>) in epilepsy Open
Epilepsy is a chronic neurological disorder manifested by recurring unprovoked seizures resulting from an imbalance in the inhibitory and excitatory neurotransmitters in the brain. The process of epileptogenesis involves a complex interpla…
View article: New insights on the potential effect of progesterone in Covid‐19: Anti‐inflammatory and immunosuppressive effects
New insights on the potential effect of progesterone in Covid‐19: Anti‐inflammatory and immunosuppressive effects Open
Background : Coronavirus disease 2019 (COVID‐19) is a pandemic disease caused by severe acute respiratory syndrome CoV type 2 (SARS‐CoV‐2). COVID‐19 is higher in men than women and sex hormones have immune‐modulator effects during differen…
View article: Primary Hypothyroidism and Alzheimer’s Disease: A Tale of Two
Primary Hypothyroidism and Alzheimer’s Disease: A Tale of Two Open
View article: Pathogenic Role of Fibrinogen in the Neuropathology of Multiple Sclerosis: A Tale of Sorrows and Fears
Pathogenic Role of Fibrinogen in the Neuropathology of Multiple Sclerosis: A Tale of Sorrows and Fears Open
Multiple sclerosis (MS) is an autoimmune demyelinating neurodegenerative disease of the central nervous system (CNS) due to injury of the myelin sheath by immune cells. The clotting factor fibrinogen is involved in the pathogenesis of MS b…
View article: New insights on the potential effect of vinpocetine in Parkinson’s disease: one of the neglected warden and baffling topics
New insights on the potential effect of vinpocetine in Parkinson’s disease: one of the neglected warden and baffling topics Open
Vinpocetine (VPN) is an ethyl apovincaminate that has anti-inflammatory and antioxidant effects by inhibiting the expression of nuclear factor kappa B (NF-κB) and phosphodiesterase enzyme 1 (PDE-1). VPN is used in the management of stroke,…
View article: Unique Cellular Characteristics of The Splenic Marginal Zone of The Barki Sheep Make It a Powerful Immunological Defense
Unique Cellular Characteristics of The Splenic Marginal Zone of The Barki Sheep Make It a Powerful Immunological Defense Open
The marginal zone is a unique structure at the marginal area of the splenic white pulp, acting as a transient region where newly arriving cells, antigens, and blood are filtered.The splenic marginal zone of the Barki sheep surrounds the wh…
View article: New Insights into the Splenic Stroma of the Barki Sheep: A Histological, Immunohistochemical, Ultrastructural and Morphometrical Study
New Insights into the Splenic Stroma of the Barki Sheep: A Histological, Immunohistochemical, Ultrastructural and Morphometrical Study Open
Introduction: Spleen is the largest secondary lymphatic organ in the body designed to respond immunologically to antigens circulating in the blood.Aim: describe the histoarchitectural features and morphometrical characters of the stroma of…
View article: Temporospatial characterization of the bronchus associated lymphoid tissue (BALT) of the one humped camel (Camelus dromedarius)
Temporospatial characterization of the bronchus associated lymphoid tissue (BALT) of the one humped camel (Camelus dromedarius) Open