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View article: Comparative safety of drug therapies used in hemophilia A and B in Canada: a multi-center, retrospective study
Comparative safety of drug therapies used in hemophilia A and B in Canada: a multi-center, retrospective study Open
View article: Reporting of Race and Ethnicity in Studies of Interventions Published in the Canadian Medical Association Journal: A Methodological Review
Reporting of Race and Ethnicity in Studies of Interventions Published in the Canadian Medical Association Journal: A Methodological Review Open
Background: In 2023, the Canadian Medical Association Journal (CMAJ) published guidance on reporting race and ethnicity. This new guidance is a welcome development, yet unanswered questions remain regarding the reporting of race and ethnic…
View article: Non-clotting factor therapies for preventing bleeds in people with congenital hemophilia A or B
Non-clotting factor therapies for preventing bleeds in people with congenital hemophilia A or B Open
Evidence from RCTs shows that prophylaxis using non-clotting factor therapies compared with on-demand treatment may reduce bleeding events, increase the percentage of individuals with zero bleeds, increase the incidence of non-serious adve…
View article: Referee report. For: Perioperative management in haemophilia with extended half-life factors: a case series [version 1; peer review: 2 approved with reservations]
Referee report. For: Perioperative management in haemophilia with extended half-life factors: a case series [version 1; peer review: 2 approved with reservations] Open
View article: Inhibitors in hemophilia: association with surgery plans and outcomes in a retrospective cohort study
Inhibitors in hemophilia: association with surgery plans and outcomes in a retrospective cohort study Open
View article: Risk factors for bleeding in people living with hemophilia A and B treated with regular prophylaxis: A systematic review of the literature
Risk factors for bleeding in people living with hemophilia A and B treated with regular prophylaxis: A systematic review of the literature Open
View article: Non-clotting factor therapies for preventing bleeds in people with hemophilia
Non-clotting factor therapies for preventing bleeds in people with hemophilia Open
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: This review aims to assess the effects (clinical, economic, patient‐reported and adverse outcomes) of non‐clotting factor therapies for preventing blee…
View article: Clotting factor concentrates for preventing bleeding and bleeding-related complications in previously treated individuals with haemophilia A or B
Clotting factor concentrates for preventing bleeding and bleeding-related complications in previously treated individuals with haemophilia A or B Open
Ten trials (including 608 participants) were eligible for inclusion. Eight of the trials (477 participants) had arms comparing two or more prophylactic regimens to one another and four of the trials (n = 258) compared prophylaxis to on-dem…
View article: Missed opportunities for pneumococcal vaccinations in high-risk and older adults in the United States
Missed opportunities for pneumococcal vaccinations in high-risk and older adults in the United States Open
Pneumococcal vaccination rates remain sub-optimal in high-risk adult populations. This analysis quantified "missed opportunities," defined as number of healthcare encounters in unvaccinated patients who are recommended to be vaccinated. Th…
View article: Relative Clinical and Cost Burden of Community-Acquired Pneumonia Hospitalizations in Older Adults in the United States—A Cross-Sectional Analysis
Relative Clinical and Cost Burden of Community-Acquired Pneumonia Hospitalizations in Older Adults in the United States—A Cross-Sectional Analysis Open
The relative burden of community-acquired pneumonia (CAP) in older adults (≥65 years old) compared to other serious diseases is important to prioritize preventive treatment. A retrospective analysis was conducted using the 2014 National Re…