Oktay Bozkurt
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View article: Aneurysmal bone cysts (ABC): Retrospective analysis of two hundred and fifty eight cases
Aneurysmal bone cysts (ABC): Retrospective analysis of two hundred and fifty eight cases Open
Purpose Aneurysmal bone cysts (ABCs) are bone tumours characterised by blood-filled cystic lesions. Management strategies for ABCs vary widely and lack consensus. This study aims to evaluate outcomes in 258 patients and investigate the fac…
View article: Prognostic Significance of Glyoxalase-1 Enzyme Activity in Metastatic Pancreatic Cancer Patients
Prognostic Significance of Glyoxalase-1 Enzyme Activity in Metastatic Pancreatic Cancer Patients Open
In previous studies, excessive expression of Glyoxalase-1 enzyme (GLO-1) has been reported in various tumor tissues and cells, and it has been shown to be associated with poor prognosis in some tumors. In this study, we examined the relati…
View article: Second Line Therapies After Tyrosine Kinase Inhibitory in Metastatic Renal Cell Carcinoma
Second Line Therapies After Tyrosine Kinase Inhibitory in Metastatic Renal Cell Carcinoma Open
Objective: Controversy exists over the choice of 2nd-line drugs after the progression of 1st-line tyrosine kinase inhibitors (TKIs) for patients unable to receive 1st-line immunotherapy. We compared the efficacy of 2nd-line treatments afte…
View article: The Role of Clinicopathological Features in Tyrosine Kinase Inhibitory Duration in EGFR Mutant Metastatic Non-Small Cell Lung Cancer
The Role of Clinicopathological Features in Tyrosine Kinase Inhibitory Duration in EGFR Mutant Metastatic Non-Small Cell Lung Cancer Open
Background: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are effective treatments for EGFR mutant (EGFRm) metastatic non-small cell lung cancer (mNSCLC). However, the benefit of EGFR-TKIs varies. We aimed to dete…
View article: Evaluating diagnostic performance: A comparative analysis of cell-free DNA and serological test in hepatic cystic Echinococcosis
Evaluating diagnostic performance: A comparative analysis of cell-free DNA and serological test in hepatic cystic Echinococcosis Open
Cystic Echinococcosis (CE) is a zoonotic disease caused by Echinococcus granulosus sensu lato. Diagnosing CE primarily relies on imaging techniques, and there is a crucial need for an objective laboratory test to enhance the diagnostic pro…
View article: Aneurysmal Bone Cysts (Abc): Retrospective Analysis of 258 Cases
Aneurysmal Bone Cysts (Abc): Retrospective Analysis of 258 Cases Open
Puspose: Aneurysmal bone cysts (ABCs) are bone tumours characterised by blood-filled cystic lesions. Management strategies for ABCs vary widely and lack consensus. This study aims to evaluate outcomes in 258 patients and investigate the fa…
View article: Efficacy and Tolerability of First-Line Anti-eGFR and Anti-VEGF Therapy in Elderly Patients with Ras-Wild Metastatic Colon Cancer
Efficacy and Tolerability of First-Line Anti-eGFR and Anti-VEGF Therapy in Elderly Patients with Ras-Wild Metastatic Colon Cancer Open
Introduction: Adding targeted agents to chemotherapy for metastatic colorectal cancer increases survival. There have been no clinical trials in older populations comparing the efficacy of the targeted agents. We aimed to compare the effica…
View article: The effect of albumin to alkaline phosphatase ratio on survival in patients with metastatic bone sarcomas
The effect of albumin to alkaline phosphatase ratio on survival in patients with metastatic bone sarcomas Open
Objective: To investigate the effect of albumin to alkaline phosphatase ratio (AALPR) at survival in patients with metastatic bone sarcomas. Patients and Methods: 60 patients with metastatic bone sarcomas were included in the study. The re…
View article: Prognostic significance of prognostic nutritional index and hemoglobin to red cell distribution width ratio in metastatic colorectal cancer patients
Prognostic significance of prognostic nutritional index and hemoglobin to red cell distribution width ratio in metastatic colorectal cancer patients Open
Aims: Malnutrition and systemic inflammation are poor prognostic factors in cancer. Prognostic nutritional index (PNI) and Hemoglobin to red blood cell distribution witdh (HRR) are considered indicators of malnutrition and systemic inflamm…
View article: Does Cyclin-dependent Kinase 4/6 Inhibitor Toxicity Predict Treatment Response in Metastatic Hormone Positive Breast Cancer?
Does Cyclin-dependent Kinase 4/6 Inhibitor Toxicity Predict Treatment Response in Metastatic Hormone Positive Breast Cancer? Open
In estrogen and/or progesterone receptor expression (hormone receptor [HR]-positive) without human epidermal growth factor receptor 2 (HER2) overexpression (HR + /HER2 − ) metastatic breast cancer (MBC), a significant progression-free surv…
View article: Impact of prognostic factors on platinum response in extrapulmonary neuroendocrine carcinoma
Impact of prognostic factors on platinum response in extrapulmonary neuroendocrine carcinoma Open
Aim: Extrapulmonary neuroendocrine carcinomas are rare tumors and clinical trials for their treatment are limited.In this study, we aimed to determine the impact of clinicopathological and prognostic factors on platinum response in patient…
View article: P-92 Real-life experience with maintenance chemotherapy plus biologics after the first-line treatment of RAS wild-type metastatic colon cancer (mCRC): A multicenter Onco-Colon Turkey study
P-92 Real-life experience with maintenance chemotherapy plus biologics after the first-line treatment of RAS wild-type metastatic colon cancer (mCRC): A multicenter Onco-Colon Turkey study Open
Background:The guidelines support the use of the epidermal growth factor receptor (EGFR) inhibitors panitumumab or cetuximab for the treatment of metastatic colorectal cancer (mCRC) on significant clinical benefits in patients with wild-ty…
View article: Is SUVmax of 18F-FDG PET/CT Predictive Factor for Malignancy in Gastrointestinal Tract?
Is SUVmax of 18F-FDG PET/CT Predictive Factor for Malignancy in Gastrointestinal Tract? Open
Background: Increasing use of 18 F-FDG PET/CT in cancer patients, has led to more common detection of 18 F-FDG uptake in the gastrointestinal tract (GIT). Aims: The objective of this study was to assess 18 F-FDG uptake in incidental and kn…
View article: A comparison of cisplatin cumulative dose and cisplatin schedule in patients treated with concurrent chemo-radiotherapy in nasopharyngeal carcinoma
A comparison of cisplatin cumulative dose and cisplatin schedule in patients treated with concurrent chemo-radiotherapy in nasopharyngeal carcinoma Open
Introduction: Three-weekly cisplatin dose is accepted for standard treatment for concurrent chemo-radiotherapy in nasopharyngeal carcinoma. However, different chemotherapy schedules are presented in the literature. Objective: We intend to …
View article: Role of Pretreatment Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio as Prognostic Predictors for Survival in Metastatic Bladder Cancer Patients Receiving Fist-Line Chemotherapy
Role of Pretreatment Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio as Prognostic Predictors for Survival in Metastatic Bladder Cancer Patients Receiving Fist-Line Chemotherapy Open
Objective: The correlation between neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) and the prognosis of different cancers has been determined by a series of studies. The role of these inflammatory markers as def…
View article: The relationship between dialysis adequacy and the rate of change in uric acid level by hemodialysis
The relationship between dialysis adequacy and the rate of change in uric acid level by hemodialysis Open
Aim: Although one of the commonly used methods for determining dialysis adequacy is the urea kinetic model, it is not the gold standard. Different parameters are needed to determine dialysis adequacy. In our study, we investigated the rela…
View article: THE RELATIONSHIP BETWEEN NEUTROPHİL / LYMPHOCYTES RATIO AND PLATELET / LYMPHOCYTES RATIO WITH PROGNOSIS IN OPERATED STAGE 1-2 OF NON- SMALL CELL LUNG CANCER DISEASE: ONE CENTRAL EXPERIENCE
THE RELATIONSHIP BETWEEN NEUTROPHİL / LYMPHOCYTES RATIO AND PLATELET / LYMPHOCYTES RATIO WITH PROGNOSIS IN OPERATED STAGE 1-2 OF NON- SMALL CELL LUNG CANCER DISEASE: ONE CENTRAL EXPERIENCE Open
Amaç:Nötrofil/lenfosit oranı (NLO) ve platelet/lenfosit oranı (PLO) ile çeşitlikanserlerin prognozu arasındaki ilişki gösterilmiştir. Ancak NLO ve PLO’ nun küçükhücreli dışı akciğer kanseri (KHDAK) prognozuna etkisi hala tartışmalıdır. Buç…
View article: Rechallenge chemotherapy as a third line treatment option for metastatic colorectal carcinoma
Rechallenge chemotherapy as a third line treatment option for metastatic colorectal carcinoma Open
Amaç: Metastatik kolorektal kanser (mCRC) sağkalımı nedeniyle irinotekan ve oksaliplatin esaslı rejim sonrasında üçüncü basamak tedavide şu an etkili bir seçenek mevcut. Seçici hastalarda tekrarlayan bir kemoterapi rejimi (yeniden sorgulam…
View article: Hormone receptor status and survival of medullary breast cancer patients
Hormone receptor status and survival of medullary breast cancer patients Open
Median follow-up time was 54 (4-272) months. Median patient age at the time of diagnosis was 47 years old (26-90). Of the patients, 91.5% were triple negative. Five-year recurrence free survival time (RFS) rate was 87.4% and overalll survi…
View article: The assessment of bone marrow infiltration with 18FDG-PET in non-haematopoietic solid tumors
The assessment of bone marrow infiltration with 18FDG-PET in non-haematopoietic solid tumors Open
ÖZET GİRİŞ ve AMAÇ: Çalışmamızın amacı, solid tümörlere bağlı kemik iliği metastazı (KİM) düşünülen ve kemik iliği biyopsisi (KİB) yapılmış hastalarda 18F-Fluorodeoxyglucose kullanılarak yapılan positron emission bilgisayarlı tomografisini…