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View article: Exceptional Response in a Patient with mRCC Through Precision-Guided Treatment Involving Immunotherapy Rechallenge with Temsirolimus and Bevacizumab
Exceptional Response in a Patient with mRCC Through Precision-Guided Treatment Involving Immunotherapy Rechallenge with Temsirolimus and Bevacizumab Open
Comprehensive genomic profiling (CGP) and the subsequent discussions in molecular tumor boards (MTBs) are becoming an integral part of personalized cancer care. The patient with metastatic renal cell carcinoma (mRCC) presented here demonst…
View article: Case report: Near-complete response to neratinib-based treatment in HR-positive HER2-amplified metastatic breast cancer refractory to trastuzumab deruxtecan
Case report: Near-complete response to neratinib-based treatment in HR-positive HER2-amplified metastatic breast cancer refractory to trastuzumab deruxtecan Open
Breast cancer (BC) is the leading cause of cancer-related mortality among women. The backbone of first-line treatment in HR+/HER2+ BC is dual anti-HER2 blockade combined with taxane chemotherapy. Although this regimen exhibits high rates o…
View article: P1117 A 24-year, single-centre perianal fistulizing Crohn’s disease cohort: documentation of demographics and factors influencing clinical and radiological remission
P1117 A 24-year, single-centre perianal fistulizing Crohn’s disease cohort: documentation of demographics and factors influencing clinical and radiological remission Open
Background Radiological remission (RR), is the ultimate treatment goal in treatment of complex perianal fistula (cPAF) in Crohn’s disease (CD). In this study, we analysed cPAF disease characteristics and RR-related factors in a CD cohort. …
View article: Efficiency of intranodal lymphangiography in the treatment of postoperative lymphatic leakage
Efficiency of intranodal lymphangiography in the treatment of postoperative lymphatic leakage Open
Intranodal lymphangiography appears to be a safe and effective minimally invasive treatment option for CL following thyroid and thoraco-abdominal surgeries, demonstrating acceptable technical and clinical success rates.
View article: Radiological Perspectives in Congenital Sensorineural Hearing Loss: Insights from Cochlear Implant Candidates
Radiological Perspectives in Congenital Sensorineural Hearing Loss: Insights from Cochlear Implant Candidates Open
Objectives: Congenital hearing loss is a significant health concern, with diverse etiologies encompassing cochlear and cochleovestibular pathologies. Preoperative radiological evaluation in cochlear implant candidates is pivotal for treatm…
View article: Radiological Perspectives in Congenital Sensorineural Hearing Loss: Insights from Cochlear Implant Candidates
Radiological Perspectives in Congenital Sensorineural Hearing Loss: Insights from Cochlear Implant Candidates Open
Objectives: Congenital hearing loss is a significant health concern, with diverse etiologies encompassing cochlear and cochleovestibular pathologies. Preoperative radiological evaluation in cochlear implant candidates is pivotal for treatm…
View article: Personalized Immunotherapy Achieves Complete Response in Metastatic Adenoid Cystic Carcinoma Despite Lack of Conventional Biomarkers
Personalized Immunotherapy Achieves Complete Response in Metastatic Adenoid Cystic Carcinoma Despite Lack of Conventional Biomarkers Open
There is currently no effective treatment strategy for recurrent/metastatic adenoid cystic carcinoma (R/M ACC). Furthermore, recent single-agent and combination immunotherapy trials have failed in unselected ACC cohorts, unlike non-ACC sal…
View article: Personalized Immunotherapy Achieves Complete Response in Metastatic Adenoid Cystic Carcinoma Despite Lack of Conventional Biomarkers
Personalized Immunotherapy Achieves Complete Response in Metastatic Adenoid Cystic Carcinoma Despite Lack of Conventional Biomarkers Open
There is currently no effective treatment strategy for the recurrent/metastatic adenoid cystic carcinoma (R/M ACC). Furthermore, recent single-agent and combination immunotherapy trials have failed in unselected ACC cohorts unlike non-ACC …
View article: Elacestrant Plus Alpelisib in an ESR1 and PIK3CA Co-mutated and Heavily Pretreated Metastatic Breast Cancer: The First Case for Combination Efficacy and Safety
Elacestrant Plus Alpelisib in an ESR1 and PIK3CA Co-mutated and Heavily Pretreated Metastatic Breast Cancer: The First Case for Combination Efficacy and Safety Open
Breast cancer (BC) is the leading cause of cancer-related mortality among women, and hormone receptor (HR)-positive subtype makes up majority of all cases. The standard-of-care (SOC) in HR+/HER2- metastatic BC (MBC) is endocrine therapy (E…
View article: Navigating uncharted territory: a case report and literature review on the remarkable response to personalized crizotinib containing combinational therapy in a pazopanib refractory patient with novel alterations
Navigating uncharted territory: a case report and literature review on the remarkable response to personalized crizotinib containing combinational therapy in a pazopanib refractory patient with novel alterations Open
This paper presents a patient with a novel Ig-like-III domain fibroblast growth factor receptor (FGFR2) alteration (W290_P307>C) along with CDKN2A/B alterations and a cadherin 1 (CDH1) alteration. Initial responsiveness to pazopanib monoth…
View article: Comparative study of imaging features in uncomplicated and complicated acute appendicitis
Comparative study of imaging features in uncomplicated and complicated acute appendicitis Open
This study provides a detailed analysis of distinct imaging findings associated with uncomplicated and complicated appendicitis. Key differentiators such as appendiceal diameter, periappendiceal air, effusion, and intraluminal appendicolit…
View article: Elacestrant plus alpelisib in an <i>ESR1</i> and <i>PIK3CA</i> co-mutated and heavily pretreated metastatic breast cancer: the first case report for combination efficacy and safety
Elacestrant plus alpelisib in an <i>ESR1</i> and <i>PIK3CA</i> co-mutated and heavily pretreated metastatic breast cancer: the first case report for combination efficacy and safety Open
Breast cancer (BC) is the leading cause of cancer-related mortality among women, and hormone receptor (HR)-positive subtype makes up the majority of all cases. The standard of care in HR + /HER2 − metastatic BC (MBC) is endocrine therapy (…
View article: Challenges and predictive radiological findings in the diagnosis of neuroendocrine tumors in patients with acute appendicitis
Challenges and predictive radiological findings in the diagnosis of neuroendocrine tumors in patients with acute appendicitis Open
This study identifies mural nodules and intraluminal air as significant predictors of neuroendocrine tumors in patients with acute appendicitis, emphasizing the importance of meticulous preoperative imaging evaluations. Incorporating these…
View article: Exceptional Response to MEK Inhibition in a Patient With RAF1-Mutant Myxofibrosarcoma: Case Report and Mechanistic Overview
Exceptional Response to MEK Inhibition in a Patient With RAF1-Mutant Myxofibrosarcoma: Case Report and Mechanistic Overview Open
Complete response to Trametinib in a heavily-pretreated sarcoma: RAF1 as a predictor of MEKi Response
View article: An Anatomical and Radiological Study of Origins of the Arteries Forming the Celiac Trunk: Clinical and Embryological Implications
An Anatomical and Radiological Study of Origins of the Arteries Forming the Celiac Trunk: Clinical and Embryological Implications Open
The blood supply to the most of abdominal organs is provided by the branches of CT. The SMA supply caecum, ascends colon, all of the small bowels except the upper part of duodenum. Knowledge of variable anatomy of celiac axis and SMA may b…
View article: COVID-19 Detection in Computed Tomography Images with 2D and 3D Approaches
COVID-19 Detection in Computed Tomography Images with 2D and 3D Approaches Open
Detecting COVID-19 in computed tomography (CT) or radiography images has been proposed as a supplement to the definitive RT-PCR test. We present a deep learning ensemble for detecting COVID-19 infection, combining slice-based (2D) and volu…
View article: COVID-19 Detection in Computed Tomography Images with 2D and 3D Approaches
COVID-19 Detection in Computed Tomography Images with 2D and 3D Approaches Open
Detecting COVID-19 in computed tomography (CT) or radiography images has been proposed as a supplement to the definitive RT-PCR test. We present a deep learning ensemble for detecting COVID-19 infection, combining slice-based (2D) and volu…
View article: Falciform Ligament Necrosis and Respiratory Distress due to Acute Pancreatitis
Falciform Ligament Necrosis and Respiratory Distress due to Acute Pancreatitis Open
Ligamentum falciforme separates liver from the left lateral and medial segments along the umbilical fissure and suspends the liver on the anterior wall of the abdomen. The ligamentum teres hepatis is a remnant of the obliterated umbilical …
View article: Chest Computed Tomography Findings of Eight Patients With Covid-19 Diagnosis: Case Series.
Chest Computed Tomography Findings of Eight Patients With Covid-19 Diagnosis: Case Series. Open
COVID-19 is an infectious disease caused by the virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and declared a pandemic on March 11, 2020, by the world health organization. In Turkey, the first cases began to appea…
View article: Ureteral Wall Thickness is an Independent Parameter Affecting the Success of Extracorporeal Shock Wave Lithotripsy Treatment in Ureteral Stones above the Iliac Crest
Ureteral Wall Thickness is an Independent Parameter Affecting the Success of Extracorporeal Shock Wave Lithotripsy Treatment in Ureteral Stones above the Iliac Crest Open
Background: To investigate the relationship between ureteral wall thickness (UWT) and other variables of patients who underwent extracorporeal shock wave lithotripsy (SWL) in the primary treatment of the ureteral stone above the iliac cres…
View article: Body Packers and Imaging: A Case Report
Body Packers and Imaging: A Case Report Open
Introduction: The body-packer is an international smuggler who ingests packed illicit drugs. Imaging is very important for diagnosis and management of these patients. Case report: We present a case of cocaine body-packing detected through …
View article: The Clinical and Computed Tomography Findings of Patients with COVID-19
The Clinical and Computed Tomography Findings of Patients with COVID-19 Open
Objective: To evaluate the demographic, clinical data and, computed tomography findings of patients diagnosed COVID-19. Methods: Patients who had COVID 19 suspicion in the emergency department of the university hospital in Istanbul, Turkey…
View article: The importance of computerized tomographic urography in evaluation of the patients with hematuria
The importance of computerized tomographic urography in evaluation of the patients with hematuria Open
AmaAmaç: Bu çalışmanın amacı hematüriyakınması ile gelen olgularda bilgisayarlı tomografik (BT) ürografisonuçlarının değerlendirilmesi ve hematürinin nedeninin saptanmasında BT ürografinin etkinliğininaraştırılmasıdır.Gereç ve Yöntem: Ocak…
View article: A dilemma at gray scale thyroid ultrasound: microcalcification or not? Differentiation with Acoustic Radiation Force Impulse Imaging–Virtual Touch Imaging.
A dilemma at gray scale thyroid ultrasound: microcalcification or not? Differentiation with Acoustic Radiation Force Impulse Imaging–Virtual Touch Imaging. Open
Aims: To evaluate the capacity of virtual touch imaging (VTI) of the acoustic radiation force impulse (ARFI) techniquein the differential diagnosis of micro-echogenicities in thyroid nodules. Material and methods: The study comprised 28pat…
View article: Vacuum-assisted stereotactic breast biopsy in the diagnosis and management of suspicious microcalcifications
Vacuum-assisted stereotactic breast biopsy in the diagnosis and management of suspicious microcalcifications Open
Our biposy method is fast and practical, and it is easily tolerated by patients without compromising accuracy. Patients with a diagnosis of atypia still need to undergo a diagnostic surgical procedure and those with a malignancy need to un…
View article: A Very Rare Complication of Acute Appendicitis: Appendicovesical Fistula
A Very Rare Complication of Acute Appendicitis: Appendicovesical Fistula Open
Appendicovesical fistula (AVF) is an uncommon type of enterovesical fistula and a very rare complication of acute appendicitis. Herein, we report a case of 39-year-old male patient who presented with persistent urinary tract infection, rec…
View article: Diffusion Tensor Imaging without Complex Statistical Analysis Could Be Helpful for Diagnosis
Diffusion Tensor Imaging without Complex Statistical Analysis Could Be Helpful for Diagnosis Open
Objective: Thanks to fast developing technology, visualization of fiber tracts at brain is possible. But with the new developments, data processing and interpretation are becoming more difficult. Actually interpretations in these fields ar…