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View article: Proteomimetic polymer blocks mitochondrial damage, rescues Huntington’s neurons, and slows onset of neuropathology in vivo
Proteomimetic polymer blocks mitochondrial damage, rescues Huntington’s neurons, and slows onset of neuropathology in vivo Open
Recently, it has been shown that blocking the binding of valosin-containing protein (VCP) to mutant huntingtin (mtHtt) can prevent neuronal mitochondrial autophagy in Huntington’s disease (HD) models. Herein, we describe the development an…
View article: Long-Circulating Vasoactive 1,18-Octadecanedioic Acid–Terlipressin Conjugate
Long-Circulating Vasoactive 1,18-Octadecanedioic Acid–Terlipressin Conjugate Open
Hepatorenal syndrome (HRS) is a life-threatening complication of end-stage liver disease first reported over a century ago, but its management still poses an unmet challenge. A therapeutic agent found to stabilize the condition is a short …
View article: Intrinsic fluorescence of nucleobase crystals
Intrinsic fluorescence of nucleobase crystals Open
Nucleobase crystals exhibit intrinsic fluorescence in the visible range and red edge excitation shift.
View article: Dipeptide Nanostructure Assembly and Dynamics <i>via in Situ</i> Liquid-Phase Electron Microscopy
Dipeptide Nanostructure Assembly and Dynamics <i>via in Situ</i> Liquid-Phase Electron Microscopy Open
In this paper, we report the in situ growth of FF nanotubes examined via liquid-cell transmission electron microscopy (LCTEM). This direct, high spatial, and temporal resolution imaging approach allowed us to observe the growth of peptide-…
View article: Structural Transformation and Morphology of Dipeptide Supramolecular Assemblies by Liquid-phase TEM
Structural Transformation and Morphology of Dipeptide Supramolecular Assemblies by Liquid-phase TEM Open
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View article: Biomolecular Densely Grafted Brush Polymers: Oligonucleotides, Oligosaccharides and Oligopeptides
Biomolecular Densely Grafted Brush Polymers: Oligonucleotides, Oligosaccharides and Oligopeptides Open
In this Minireview, we describe synthetic polymers densely functionalized with sequence‐defined biomolecular sidechains. We focus on synthetic brush polymers of oligonucleotides, oligosaccharides, and oligopeptides, prepared via graft‐thro…
View article: CCDC 1881596: Experimental Crystal Structure Determination
CCDC 1881596: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Molecular self‐assembly using peptide nucleic acids
Molecular self‐assembly using peptide nucleic acids Open
Peptide nucleic acids (PNAs) are extensively studied for the control of genetic expression since their design in the 1990s. However, the application of PNAs in nanotechnology is much more recent. PNAs share the specific base‐pair recogniti…
View article: Photonic Crystals: Spectral Transition in Bio‐Inspired Self‐Assembled Peptide Nucleic Acid Photonic Crystals (Adv. Mater. 11/2016)
Photonic Crystals: Spectral Transition in Bio‐Inspired Self‐Assembled Peptide Nucleic Acid Photonic Crystals (Adv. Mater. 11/2016) Open
Guanine crystals are present in the skin of a wide range of animals, providing vivid structural colors. Growing guanine crystals with similar optical properties in vitro is a still unmet challenge. Using guanine-based peptide nucleic acid …
View article: Spectral Transition in Bio‐Inspired Self‐Assembled Peptide Nucleic Acid Photonic Crystals
Spectral Transition in Bio‐Inspired Self‐Assembled Peptide Nucleic Acid Photonic Crystals Open
The self-assembly of guanine-based peptide nucleic acid monomers into photonic crystals is described. A highly reflective lattice of guanine nanocrystals is found in the skin and ocular tissues of different species providing vivid structur…