Ora T. Cohen
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View article: Elongated Particles Show a Preferential Uptake in Invasive Cancer Cells
Elongated Particles Show a Preferential Uptake in Invasive Cancer Cells Open
Mechanically driven cellular preference for drug carriers can enhance selectivity in cancer therapy, underscoring the importance of understanding the physical aspects of particle uptake. In this study, it was hypothesized that elongated pa…
View article: Particle uptake in cancer cells can predict malignancy and drug resistance using machine learning
Particle uptake in cancer cells can predict malignancy and drug resistance using machine learning Open
Tumor heterogeneity is a primary factor that contributes to treatment failure. Predictive tools, capable of classifying cancer cells based on their functions, may substantially enhance therapy and extend patient life span. The connection b…
View article: Two dominant timescales of cytoskeletal crosslinking in the viscoelastic response of the cytoplasm
Two dominant timescales of cytoskeletal crosslinking in the viscoelastic response of the cytoplasm Open
Cells precisely regulate their frequency-dependent viscoelastic properties in response to chemical and mechanical cues. We use optical trap-based active microrheology using intracellular probes to measure the cytoplasmic mechanical respons…