Oreste Marrone
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View article: Spectrum of sleep‐disordered breathing and quality of sleep in adolescent and adult patients with spinal muscular atrophy
Spectrum of sleep‐disordered breathing and quality of sleep in adolescent and adult patients with spinal muscular atrophy Open
Summary Sleep‐disordered breathing is common among children with spinal muscular atrophy, but has been hardly studied among adult subjects. Little is known about sleep quality in spinal muscular atrophy. The aims of this study were to eval…
View article: Age Related Burden of Swallowing in Adult Patients Affected by Duchenne Muscular Dystrophy
Age Related Burden of Swallowing in Adult Patients Affected by Duchenne Muscular Dystrophy Open
Background: In Duchenne muscular dystrophy (DMD), dysphagia is a common but often overlooked symptom, which may affect quality of life (QoL). Its possible causes are progressive deterioration of muscle groups involved in swallowing functio…
View article: European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea
European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea Open
Treatment of obstructive sleep apnoea (OSA) in adults is evolving, as new therapies have been explored and introduced in clinical practice, while other approaches have been refined or reconsidered. In this European Respiratory Society (ERS…
View article: Short-Term Effects of Pressure Controlled Versus Volume Controlled Noninvasive Ventilation in Subjects With Amyotrophic Lateral Sclerosis
Short-Term Effects of Pressure Controlled Versus Volume Controlled Noninvasive Ventilation in Subjects With Amyotrophic Lateral Sclerosis Open
In the short term, PC-CMV may be a preferred NIV modality to VC-CMV for patients with amyotrophic lateral sclerosis, even when both NIV modes are similarly effective in the correction of hypoventilation. Evaluation of the effectiveness of …
View article: Excessive Daytime Sleepiness in Obstructive Sleep Apnea Patients Treated With Continuous Positive Airway Pressure: Data From the European Sleep Apnea Database
Excessive Daytime Sleepiness in Obstructive Sleep Apnea Patients Treated With Continuous Positive Airway Pressure: Data From the European Sleep Apnea Database Open
Excessive daytime sleepiness (EDS) is a symptom of obstructive sleep apnea (OSA) that resolves under treatment with continuous positive airway pressure (CPAP). In some patients, sleepiness persists despite CPAP treatment. We retrospectivel…
View article: Positive airway pressure (PAP) treatment reduces glycated hemoglobin (HbA1c) levels in obstructive sleep apnea patients with concomitant weight loss: Longitudinal data from the ESADA
Positive airway pressure (PAP) treatment reduces glycated hemoglobin (HbA1c) levels in obstructive sleep apnea patients with concomitant weight loss: Longitudinal data from the ESADA Open
Summary Patients with obstructive sleep apnea (OSA) are at increased risk of developing metabolic disease such as diabetes. The effects of positive airway pressure on glycemic control are contradictory. We therefore evaluated the change in…
View article: Determinants of Sleepiness at Wheel and Missing Accidents in Patients With Obstructive Sleep Apnea
Determinants of Sleepiness at Wheel and Missing Accidents in Patients With Obstructive Sleep Apnea Open
Study Objectives Motor-vehicle crashes are frequent in untreated OSA patients but there is still uncertainty on prevalence as well as physiological or clinical determinants of sleepiness at the wheel (SW) in OSA patients. We assessed deter…
View article: Superior hypertension control with betablockade in the European Sleep Apnea Database
Superior hypertension control with betablockade in the European Sleep Apnea Database Open
Background Arterial hypertension is highly prevalent and frequently difficult to control in patients with obstructive sleep apnea (OSA). High sympathetic activity is a hallmark physiological phenomenon in OSA. We hypothesized that antihype…
View article: European Respiratory Society statement on sleep apnoea, sleepiness and driving risk
European Respiratory Society statement on sleep apnoea, sleepiness and driving risk Open
Obstructive sleep apnoea (OSA) is highly prevalent and is a recognised risk factor for motor vehicle accidents (MVA). Effective treatment with continuous positive airway pressure has been associated with a normalisation of this increased a…
View article: Sleep Apnea and the Kidney
Sleep Apnea and the Kidney Open
Purpose of Review There are some uncertainties about the interactions between obstructive sleep apnea (OSA) and chronic kidney disease (CKD). We critically reviewed recent studies on this topic with a focus on experimental and clinical evi…
View article: Unique sleep‐stage transitions determined by obstructive sleep apnea severity, age and gender
Unique sleep‐stage transitions determined by obstructive sleep apnea severity, age and gender Open
Summary In obstructive sleep apnea, patients’ sleep is fragmented leading to excessive daytime sleepiness and co‐morbidities like arterial hypertension. However, traditional metrics are not always directly correlated with daytime sleepines…
View article: Decrease in blood pressure during continuous positive airway pressure treatment for obstructive sleep apnoea: still searching for predictive factors
Decrease in blood pressure during continuous positive airway pressure treatment for obstructive sleep apnoea: still searching for predictive factors Open
High blood pressure (BP) and non-dipping 24-hour BP profile may help to predict BP decrease after obstructive sleep apnoea treatment by CPAP.However, specific, highly reproducible traits associated with BP responsiveness to CPAP must still…
View article: Comment to the Editorial by KS Park and EW Kang “Is only fixed positive airway pressure a robust tool for kidney protection in patients with obstructive sleep apnea?”
Comment to the Editorial by KS Park and EW Kang “Is only fixed positive airway pressure a robust tool for kidney protection in patients with obstructive sleep apnea?” Open
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View article: Obstructive sleep apnea and comorbidities: a dangerous liaison
Obstructive sleep apnea and comorbidities: a dangerous liaison Open
Obstructive sleep apnea (OSA) is a highly prevalent disease, and is traditionally associated with increased cardiovascular risk. The role of comorbidities in OSA patients has emerged recently, and new conditions significantly associated wi…
View article: Obstructive sleep apnea and comorbidities: a dangerous liaison
Obstructive sleep apnea and comorbidities: a dangerous liaison Open
Obstructive sleep apnea (OSA) is a highly prevalent disease, and is traditionally associated with increased cardiovascular risk. The role of comorbidities in OSA patients has emerged recently, and new conditions significantly associated wi…
View article: Blood-pressure variability in patients with obstructive sleep apnea: current perspectives
Blood-pressure variability in patients with obstructive sleep apnea: current perspectives Open
Obstructive sleep apnea (OSA) is often associated with hypertension and other cardiovascular diseases. Blood pressure (BP) variability is part of the assessment of cardiovascular risk. In OSA, BP variability has been studied mainly as very…
View article: Use of autobilevel ventilation in patients with obstructive sleep apnea: An observational study
Use of autobilevel ventilation in patients with obstructive sleep apnea: An observational study Open
Summary Continuous positive airway pressure (CPAP) is the first‐choice treatment for obstructive sleep‐disordered breathing. Automatic bilevel ventilation can be used to treat obstructive sleep‐disordered breathing when CPAP is ineffective…
View article: Obstructive sleep apnea and chronic kidney disease: open questions on a potential public health problem
Obstructive sleep apnea and chronic kidney disease: open questions on a potential public health problem Open
The relationship between obstructive sleep apnea (OSA) and chronic kidney disease (CKD) is the object of an increasing interest. OSA and CKD share some common risk factors, like older age and obesity, and both of them have complex interrel…
View article: Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment
Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment Open
In all fields of medicine, major efforts are currently dedicated to improve the clinical, physiological and therapeutic understanding of disease, and obstructive sleep apnoea (OSA) is no exception. The personalised medicine approach is rel…