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View article: Antioxidant Potential of Polyphenolic Compounds, Sources, Extraction, Purification and Characterization Techniques: A Focused Review
Antioxidant Potential of Polyphenolic Compounds, Sources, Extraction, Purification and Characterization Techniques: A Focused Review Open
Polyphenolic compounds, which are abundant phenolic metabolites in plants, have attracted significant attention because of their diverse biological activities and robust antioxidant properties. This review uniquely describes the extraction…
View article: Potential anticancer effects of Peganum harmala in human papillomavirus-related cervical and head and neck cancer cells
Potential anticancer effects of Peganum harmala in human papillomavirus-related cervical and head and neck cancer cells Open
Background P. harmala L ( P. harmala ) has a longstanding role in ethnomedical treatments. Its reported anticancer effects have led to increased research interest; however, its antineoplastic properties on cervical and head and neck (HN) c…
View article: Mechanisms Underlying the Cognitive Benefits of Solanum macrocarpon Leaf n-Butanol Extract: Acetylcholinesterase Inhibition and Oxidative Stress Modulation
Mechanisms Underlying the Cognitive Benefits of Solanum macrocarpon Leaf n-Butanol Extract: Acetylcholinesterase Inhibition and Oxidative Stress Modulation Open
This study investigates the neuroprotective and anxiolytic effects of Solanum macrocarpon L. leaf n-butanol extract (SMB) in a zebrafish model of scopolamine (SCOP; 100 μM)-induced cognitive and behavioral impairments. SCOP, a muscarinic r…
View article: 3-Hydroxytyrosol as a phenolic cholinesterase inhibitor with antiamnesic activity: a multimethodological study of selected plant phenolics
3-Hydroxytyrosol as a phenolic cholinesterase inhibitor with antiamnesic activity: a multimethodological study of selected plant phenolics Open
Background Plant phenolics are increasingly being investigated for their diverse biological activities, including neuroprotective effects relevant to conditions like Alzheimer’s disease. Objective The neurobiological potential of 37 plant …
View article: Evaluation of Enzyme Inhibitory Effects and Phytochemical Analysis by LC-Q-ToF MS of Some Polygonum L. Species Growing in Türkiye
Evaluation of Enzyme Inhibitory Effects and Phytochemical Analysis by LC-Q-ToF MS of Some Polygonum L. Species Growing in Türkiye Open
Polygonum species have strong biological activity due to their important bioactive components. Polygonum species have been studied for enzyme inhibition activity, wound healing, anti-inflammatory, antibacterial, antiviral, antioxidant effe…
View article: Solanum macrocarpon L. Ethanolic Leaf Extract Exhibits Neuroprotective and Anxiolytic Effects in Scopolamine-Induced Amnesic Zebrafish Model
Solanum macrocarpon L. Ethanolic Leaf Extract Exhibits Neuroprotective and Anxiolytic Effects in Scopolamine-Induced Amnesic Zebrafish Model Open
Background/Objectives: Solanum macrocarpon L. has been studied for its neuroprotective potential and memory-enhancing properties. Research suggests that bioactive compounds, including flavonoids, alkaloids, and phenolics, contribute to its…
View article: Evaluation of the Anti-Aging Properties of Ethanolic Extracts from Selected Plant Species and Propolis by Enzyme Inhibition Assays and 2D/3D Cell Culture Methods
Evaluation of the Anti-Aging Properties of Ethanolic Extracts from Selected Plant Species and Propolis by Enzyme Inhibition Assays and 2D/3D Cell Culture Methods Open
Background: Skin aging is a complex biological process affected by internal and external factors that disrupt the skin structure, especially in sun-exposed areas. Elastin and collagen in the dermis layer, responsible for the skin’s resista…
View article: Chromatographic Analysis and Enzyme Inhibition Potential of Reynoutria japonica Houtt.: Computational Docking, ADME, Pharmacokinetic, and Toxicokinetic Analyses of the Major Compounds
Chromatographic Analysis and Enzyme Inhibition Potential of Reynoutria japonica Houtt.: Computational Docking, ADME, Pharmacokinetic, and Toxicokinetic Analyses of the Major Compounds Open
Background: Reynoutria japonica Houtt. has been used for inflammatory diseases, skin burns, and high cholesterol in traditional Chinese medicine, and the roots and rhizomes of the plant were registered in the Chinese Pharmacopoeia. This st…
View article: Assessment of the Anti-Acne Properties of Some Medicinal Plants and Development of an Herbal Anti-Acne Formulation
Assessment of the Anti-Acne Properties of Some Medicinal Plants and Development of an Herbal Anti-Acne Formulation Open
Background: Acne is a prevalent dermatological condition characterized by the blockage of hair follicles and sebaceous glands, leading to the formation of acne. The anaerobe pathogen Cutibacterium acnes (formerly known as Propionibacterium…
View article: Nutritional, Chemical, Antioxidant and Antibacterial Screening of Astragalus cicer L. and Astragalus glycyphyllos L. Different Morphological Parts
Nutritional, Chemical, Antioxidant and Antibacterial Screening of Astragalus cicer L. and Astragalus glycyphyllos L. Different Morphological Parts Open
The chemical composition and biological activity of A. glycyphylos and A. cicer are scarcely investigated. In this study, the nutritional and chemical profiles of A. cicer and A. glycyphyllos, considering their different morphological part…
View article: Therapeutic Potential of Alpha- and Beta-Pinene A Miracle Gift of Nature
Therapeutic Potential of Alpha- and Beta-Pinene A Miracle Gift of Nature Open
Alpha and beta-pinene are well-known representatives of the monoterpenes group, and are found in many plants’ essential oils. A wide range of pharmacological activities have been reported, including antibiotic resistance modulation, antico…
View article: Evaluation of Selected Plant Phenolics via Beta-Secretase-1 Inhibition, Molecular Docking, and Gene Expression Related to Alzheimer’s Disease
Evaluation of Selected Plant Phenolics via Beta-Secretase-1 Inhibition, Molecular Docking, and Gene Expression Related to Alzheimer’s Disease Open
Background: The goal of the current study was to investigate the inhibitory activity of six phenolic compounds, i.e., rosmarinic acid, gallic acid, oleuropein, epigallocatechin gallate (EGCG), 3-hydroxytyrosol, and quercetin, against β-sit…
View article: Enzyme Inhibitory Activities and RP‐HPLC Analysis of <i>Geranium</i> and <i>Erodium</i> Species
Enzyme Inhibitory Activities and RP‐HPLC Analysis of <i>Geranium</i> and <i>Erodium</i> Species Open
The genera Geranium and Erodium (Geraniaceae) have been documented to possess diverse ethnopharmacological uses, including diabetes mellitus. Relevant to their ethnopharmacological use, the current study aimed to evaluate the α‐glucosidase…
View article: Neuroprotective and Nootropic Effect of Bacopa monnieri (L.) Wettst. (Brahmi) through Its In vivo Data Focused on Alzheimer’s Disease
Neuroprotective and Nootropic Effect of Bacopa monnieri (L.) Wettst. (Brahmi) through Its In vivo Data Focused on Alzheimer’s Disease Open
Bacopa monnieri (L.) Wettst. (Plantaginaceae) (BM), known as “brahmi”, is a reputed medicinal plant, particularly in Ayurvedic medicine. Since BM has been traditionally used for memory dysfunction, experimental studies at the pre-clinical …
View article: Characterization of Phenolic Profile and Biological Properties of Astragalus membranaceus Fisch. ex Bunge Commercial Samples
Characterization of Phenolic Profile and Biological Properties of Astragalus membranaceus Fisch. ex Bunge Commercial Samples Open
Astragalus membranaceus Fisch. ex Bunge (syn. Astragalus mongholicus Bunge) is one of the notable medicinal and food plants. Therefore, the aim of this study was to calculate the phenolic composition and antioxidant, antimicrobial, as well…
View article: A Narrowed Look Into Plant-Derived Testosterone 5α-Reductase Inhibitors for Androgenetic Alopecia
A Narrowed Look Into Plant-Derived Testosterone 5α-Reductase Inhibitors for Androgenetic Alopecia Open
Androgenetic alopecia (AGA) is the most prevalent cause of hair loss in men and women, resulting from a combination of genetic susceptibility and androgen hormones. Increased activity of testosterone 5α-reductase in hair follicles leads to…
View article: APPLICATIONS USED IN TREATMENT AGAINST CHEMICAL WEAPONS AND BIOTERRORISM
APPLICATIONS USED IN TREATMENT AGAINST CHEMICAL WEAPONS AND BIOTERRORISM Open
Objective: In the present study, the chemical and physical properties of various chemical warfare agents, general information about medical protection methods, current analysis methods equipment, decontamination techniques and pharmaceutic…
View article: African Under-Utilized Medicinal Leafy Vegetables Studied by Microtiter Plate Assays and High-Performance Thin-Layer Chromatography–Planar Assays
African Under-Utilized Medicinal Leafy Vegetables Studied by Microtiter Plate Assays and High-Performance Thin-Layer Chromatography–Planar Assays Open
Biological activities of six under-utilized medicinal leafy vegetable plants indigenous to Africa, i.e., Basella alba, Crassocephalum rubens, Gnetum africanum, Launaea taraxacifolia, Solanecio biafrae, and Solanum macrocarpon, were investi…
View article: Imperative Role of Natural Product Chemistry in Cosmeceutical R&D - Phytonanocosmeceuticals
Imperative Role of Natural Product Chemistry in Cosmeceutical R&D - Phytonanocosmeceuticals Open
Natural product chemistry has always been attractive for drug and cosmetic industries as natural products can address these industries very well. By consumer demand, the cosmetic industry is looking for innovative, safer, more effective, a…
View article: Potential of Mushrooms Bioactive for the Treatment of Skin Diseases and Disorders
Potential of Mushrooms Bioactive for the Treatment of Skin Diseases and Disorders Open
Mushrooms have long been revered not only as a staple food source but also for their potential medicinal properties. Their role as a natural repository of bioactive compounds positions them uniquely in the pharmaceutical domain, with parti…
View article: Enzyme inhibitory and antioxidant activities and HPLC quantification of chlorogenic acid in Helichrysum stoechas (L.) Moench and H. stoechas subsp. barrelieri (Ten) Nyman
Enzyme inhibitory and antioxidant activities and HPLC quantification of chlorogenic acid in Helichrysum stoechas (L.) Moench and H. stoechas subsp. barrelieri (Ten) Nyman Open
The inhibitory effects of ethanol (80%) and aqueous extracts of Helichrysum stoechas (L.) Moench and H. stoechas subsp. barrelieri (Ten) Nyman on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), two sister enzymes associated w…
View article: Medicinal and mechanistic overview of artemisinin in the treatment of human diseases
Medicinal and mechanistic overview of artemisinin in the treatment of human diseases Open
Artemisinin (ART) is a bioactive compound isolated from the plant Artemisia annua and has been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial infections, and some cardiovascular diseases, especi…