Oriana Miltiadous
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View article: Scalable log-ratio lasso regression for enhanced microbial feature selection with FLORAL
Scalable log-ratio lasso regression for enhanced microbial feature selection with FLORAL Open
View article: Sugar-rich foods exacerbate antibiotic-induced microbiome injury
Sugar-rich foods exacerbate antibiotic-induced microbiome injury Open
Intestinal microbiota composition is implicated in several diseases; understanding the factors that influence it are key to elucidating host-commensal interactions and to designing microbiome-targeted therapies. We quantified how diet infl…
View article: Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease Open
View article: Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity
Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity Open
View article: High-resolution analyses of associations between medications, microbiome, and mortality in cancer patients
High-resolution analyses of associations between medications, microbiome, and mortality in cancer patients Open
View article: Enhanced Feature Selection for Microbiome Data using FLORAL: Scalable Log-ratio Lasso Regression
Enhanced Feature Selection for Microbiome Data using FLORAL: Scalable Log-ratio Lasso Regression Open
Identifying predictive biomarkers of patient outcomes from high-throughput microbiome data is of high interest, while existing computational methods do not satisfactorily account for complex survival endpoints, longitudinal samples, and ta…
View article: Burgos da Silva M, Ponce DM, Dai A, et al. Preservation of the fecal microbiome is associated with reduced severity of graft-versus-host disease. <i>Blood.</i> 2022;140(22):2385-2397.
Burgos da Silva M, Ponce DM, Dai A, et al. Preservation of the fecal microbiome is associated with reduced severity of graft-versus-host disease. <i>Blood.</i> 2022;140(22):2385-2397. Open
View article: Preservation of the fecal microbiome is associated with reduced severity of graft-versus-host disease
Preservation of the fecal microbiome is associated with reduced severity of graft-versus-host disease Open
Following allogeneic hematopoietic cell transplantation (allo-HCT), the gastrointestinal (GI) tract is frequently affected by acute graft-versus-host disease (aGVHD), the pathophysiology of which is associated with a dysbiotic microbiome. …
View article: MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome and correlate with favorable patient outcome after allogeneic HCT
MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome and correlate with favorable patient outcome after allogeneic HCT Open
Microbial diversity is associated with improved outcomes in recipients of allogeneic hematopoietic cell transplantation (allo-HCT), but the mechanism underlying this observation is unclear. In a cohort of 174 patients who underwent allo-HC…
View article: Successful treatment and integrated genomic analysis of an infant with <i>FIP1L1-RARA</i> fusion–associated myeloid neoplasm
Successful treatment and integrated genomic analysis of an infant with <i>FIP1L1-RARA</i> fusion–associated myeloid neoplasm Open
FIP1L1-RARA–a ssociated neoplasm is a very rare and aggressive disease, with only 3 previously reported cases in the literature. Here, we describe a 9-month-old boy who presented with a FIP1L1-RARA fusion–associated myelodysplastic/myelopr…
Identifying and treating refractory ITP: difficulty in diagnosis and role of combination treatment Open
View article: Immune Thrombocytopenia: Are We Stuck in the Mud or Is There Light at the End of the Tunnel?
Immune Thrombocytopenia: Are We Stuck in the Mud or Is There Light at the End of the Tunnel? Open
The differences in diagnosis and management between immune thrombocytopenia (ITP) and leukemia are striking. Leukemia diagnosis and management have evolved substantially over the past 30 years and are now relatively precise. The tendency f…
View article: Erratum: Corrigendum: Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
Erratum: Corrigendum: Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer Open
View article: Parallel 37: Hepatitis C: Pre‐Approval Clinical Studies II
Parallel 37: Hepatitis C: Pre‐Approval Clinical Studies II Open
Three hundred forty-one patients were on lamivudine, 60 were on adefovir, 188 were on entecavir, 467 were on tenofovir, and 32 were on combination therapies.ROC analysis for the predictive values of HCC scores showed that AUROC values were…
View article: Progenitor cell markers predict outcome of patients with hepatocellular carcinoma beyond Milan criteria undergoing liver transplantation
Progenitor cell markers predict outcome of patients with hepatocellular carcinoma beyond Milan criteria undergoing liver transplantation Open
View article: Massive parallel sequencing uncovers actionable FGFR2–PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma
Massive parallel sequencing uncovers actionable FGFR2–PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma Open
View article: Correction: Corrigendum: Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
Correction: Corrigendum: Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer Open