Örjan Wränge
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View article: Quantification of transcription factor-DNA binding affinity in a living cell
Quantification of transcription factor-DNA binding affinity in a living cell Open
The apparent dissociation constant (Kd) for specific binding of glucocorticoid receptor (GR) and androgen receptor (AR) to DNA was determined in vivo in Xenopus oocytes. The total nuclear receptor concentration was quantified as specifical…
View article: The polyglutamine-expanded androgen receptor has increased DNA binding and reduced transcriptional activity
The polyglutamine-expanded androgen receptor has increased DNA binding and reduced transcriptional activity Open