Orsolya Horváth
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View article: Analysis of Hungarian oncologists’, general practitioners’, and palliative medicine specialists’ attitudes toward patient transition in palliative care with narrative psychology
Analysis of Hungarian oncologists’, general practitioners’, and palliative medicine specialists’ attitudes toward patient transition in palliative care with narrative psychology Open
View article: Real World Posaconazole Pharmacokinetic Data in Paediatric Stem Cell Transplant Recipients
Real World Posaconazole Pharmacokinetic Data in Paediatric Stem Cell Transplant Recipients Open
Background: Invasive fungal disease is a significant cause of morbidity and mortality in allogeneic hematopoietic stem cell transplant (alloHSCT) recipients. Posaconazole, a broad-spectrum triazole, is widely used as prophylaxis. Methods: …
View article: Epidemiologischer Überblick mukokutaner Pilzinfektionen in München
Epidemiologischer Überblick mukokutaner Pilzinfektionen in München Open
Zusammenfassung Hintergrund und Ziel Kenntnisse über das aktuelle Spektrum von Dermatomykosen sind für die Diagnose und Therapie wichtig. Patienten und Methodik Es wurde eine retrospektive, monozentrische Analyse von mukokutanen Pilzinfekt…
View article: Epidemiological overview of mucocutaneous fungal infections in Munich
Epidemiological overview of mucocutaneous fungal infections in Munich Open
Summary Background and Objectives Knowledge about the current spectrum of dermatomycoses is important for diagnosis and therapy. Patients and Methods A retrospective, monocentric analysis of mucocutaneous fungal infections diagnosed at a l…
View article: Prediction of PSA Response after Dexamethasone Switch during Abiraterone Acetate + Prednisolone Treatment of Metastatic Castration-Resistant Prostate Cancer Patients
Prediction of PSA Response after Dexamethasone Switch during Abiraterone Acetate + Prednisolone Treatment of Metastatic Castration-Resistant Prostate Cancer Patients Open
Background: The aim was to elaborate a predictive model to find responders for the corticosteroid switch (from prednisolone to dexamethasone) at the first prostate-specific antigen (PSA) progression (≥25% increase) during abiraterone aceta…
View article: A vérvizelés okai gyermekkorban – a korszerű diagnosztika a kivizsgálás tükrében
A vérvizelés okai gyermekkorban – a korszerű diagnosztika a kivizsgálás tükrében Open
A vérvizelés hátterében a betegségek széles spektruma állhat gyermekkorban, az egyszerű és gyorsan gyógyuló húgyúti fertőzésektől a gyorsan progrediáló súlyos glomerulonephritisig, mely a vesefunkció gyors romlásához vezet. A vérvizelés ki…
View article: Multiple environmental antigens may trigger autoimmunity in psoriasis through T-cell receptor polyspecificity
Multiple environmental antigens may trigger autoimmunity in psoriasis through T-cell receptor polyspecificity Open
Introduction Psoriasis is a T-cell mediated autoimmune skin disease. HLA-C*06:02 is the main psoriasis-specific risk gene. Using a Vα3S1/Vβ13S1 T-cell receptor (TCR) from a lesional psoriatic CD8 + T-cell clone we had discovered that, as a…
View article: Immunosuppressive Therapy of Antibody-Mediated aHUS and TTP
Immunosuppressive Therapy of Antibody-Mediated aHUS and TTP Open
The recent classification of pediatric thrombotic microangiopathies (TMA) takes into consideration mechanisms of disease for guidance to targeted therapies. We present our experience with seven patients with antibody mediated atypical hemo…
View article: Publisher Correction: How to define and assess the clinically significant causes of hematuria in childhood
Publisher Correction: How to define and assess the clinically significant causes of hematuria in childhood Open
View article: Bone Turnover Marker for the Evaluation of Skeletal Remodelling in Autosomal Recessive Osteopetrosis after Haematopoietic Stem Cell Transplantation: A Case Report
Bone Turnover Marker for the Evaluation of Skeletal Remodelling in Autosomal Recessive Osteopetrosis after Haematopoietic Stem Cell Transplantation: A Case Report Open
Background: Autosomal recessive osteopetrosis (ARO) is a rare genetic disorder of bone metabolism, primarily affecting the remodelling function of osteoclasts. Haematopoietic stem cell transplantation (HSCT) is the first-line treatment for…
View article: Peripheral Bone Relapse of Paediatric TCF3-HLF Positive Acute Lymphoblastic Leukaemia during Haematopoietic Stem Cell Transplantation: A Case Report
Peripheral Bone Relapse of Paediatric TCF3-HLF Positive Acute Lymphoblastic Leukaemia during Haematopoietic Stem Cell Transplantation: A Case Report Open
The present case report features a highly uncommon form of a paediatric TCF3-HLF positive acute lymphoblastic leukaemia (ALL) relapse, an extramedullary, peripheral bone manifestation. Following complete remission, during the conditioning …
View article: How to define and assess the clinically significant causes of hematuria in childhood
How to define and assess the clinically significant causes of hematuria in childhood Open
View article: High Pretreatment Serum PD-L1 Levels Are Associated with Muscle Invasion and Shorter Survival in Upper Tract Urothelial Carcinoma
High Pretreatment Serum PD-L1 Levels Are Associated with Muscle Invasion and Shorter Survival in Upper Tract Urothelial Carcinoma Open
Programmed death ligand-1 (PD-L1) is an immune checkpoint molecule and a widely used therapeutic target in urothelial cancer. Its circulating, soluble levels (sPD-L1) were recently suggested to be associated with the presence and prognosis…
View article: Correction to: Non-lupus full-house nephropathy—immune dysregulation as a rare cause of pediatric nephrotic syndrome: Answers
Correction to: Non-lupus full-house nephropathy—immune dysregulation as a rare cause of pediatric nephrotic syndrome: Answers Open
View article: Non-lupus full-house nephropathy—immune dysregulation as a rare cause of pediatric nephrotic syndrome: Questions
Non-lupus full-house nephropathy—immune dysregulation as a rare cause of pediatric nephrotic syndrome: Questions Open
View article: Low socioeconomic position is a risk factor for delay to treatment and mortality of testicular cancer patients in Hungary, a prospective study
Low socioeconomic position is a risk factor for delay to treatment and mortality of testicular cancer patients in Hungary, a prospective study Open
View article: A béltartalom és a vizelet mikrobiom-összetételének onkológiai vonatkozásai
A béltartalom és a vizelet mikrobiom-összetételének onkológiai vonatkozásai Open
Összefoglaló. Az immunrendszer nem megfelelő működése meghatározó szerepet játszik a daganatok kialakulásában, progressziójában és az egyes terápiák hatékonyságában is. A bélrendszer baktériumai a szervezet immunitásán keresztül képesek be…
View article: Low Socioeconomic Status is a Risk Factor for Delay to Treatment and Mortality of Testicular Cancer Patients in Hungary. A Prospective Study
Low Socioeconomic Status is a Risk Factor for Delay to Treatment and Mortality of Testicular Cancer Patients in Hungary. A Prospective Study Open
Background . In Hungary, the mortality rate for testicular germ cell cancer (TGCC) is 7.6% which is significantly higher than the EU average. We prospectively evaluated the effect of socioeconomic status on patient delay, doctor’s delay, a…
View article: Az allogén vérképző őssejtátültetés korai szövődményei gyermekkorban
Az allogén vérképző őssejtátültetés korai szövődményei gyermekkorban Open
Absztrakt: Bevezetés: Az allogén vérképző őssejt-transzplantáció (tx) indikációja gyermekkorban a magas szövődményráta és a nem elhanyagolható halálozás miatt csak az életet veszélyeztető betegségekre korlátozódik. A csökkentett toxicitású…
View article: Validation of Early Increase in Complement Activation Marker sC5b-9 as a Predictive Biomarker for the Development of Thrombotic Microangiopathy After Stem Cell Transplantation
Validation of Early Increase in Complement Activation Marker sC5b-9 as a Predictive Biomarker for the Development of Thrombotic Microangiopathy After Stem Cell Transplantation Open
Hematopoietic stem cell transplantation (HSCT)-associated thrombotic microangiopathy (TA-TMA) is a multifactorial complication. Complement dysregulation may play an important role in the pathogenesis of TA-TMA. Our previous observations su…
View article: Rosazea und periorale Dermatitis: Eine monozentrische, retrospektive Analyse des klinischen Erscheinungsbildes von 1032 Patienten
Rosazea und periorale Dermatitis: Eine monozentrische, retrospektive Analyse des klinischen Erscheinungsbildes von 1032 Patienten Open
Zusammenfassung Hintergrund Rosazea ist eine häufige chronisch‐entzündliche Hauterkrankung, die circa 5,5 % der erwachsenen Bevölkerung betrifft. Unser Ziel war es, die Prävalenz und Epidemiologie von Rosazea und perioraler Dermatitis (POD…
View article: Változások az őssejt-transzplantációhoz társult thromboticus microangiopathia diagnosztikus kritériumrendszerében
Változások az őssejt-transzplantációhoz társult thromboticus microangiopathia diagnosztikus kritériumrendszerében Open
Hematopoietic stem cell transplantation associated thrombotic microangiopathy is a multifactorial complication, and has variable incidence in study populations due to different diagnostic criteria. The diversity of activity parameters, lik…
View article: KRAS-mutation status dependent effect of zoledronic acid in human non-small cell cancer preclinical models
KRAS-mutation status dependent effect of zoledronic acid in human non-small cell cancer preclinical models Open
The in vitro and in vivo inhibitory effect of zoledronic acid was based on the blockade of cell cycle in wild type KRAS-expressing human NSCLC cells. The zoledronic acid induced vascularization supported in vivo cytostatic effect. Our prec…
View article: Diagnostic performance of the “MESACUP anti-Skin profile TEST”
Diagnostic performance of the “MESACUP anti-Skin profile TEST” Open
The MESACUP anti-Skin profile TEST had a similar performance to previously produced ELISA systems. The novel kit can be used for rapid diagnosis of most common autoimmune blistering diseases and is especially suitable for identifying overl…