Osamu Dohi
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View article: Usefulness of Automated Analysis System for Microvascular Blood Flow Rate Using Magnifying Endoscopy in Early Gastric Cancer: A Multicenter Retrospective Study (With Video)
Usefulness of Automated Analysis System for Microvascular Blood Flow Rate Using Magnifying Endoscopy in Early Gastric Cancer: A Multicenter Retrospective Study (With Video) Open
Background and Aim Early gastric cancer (EGC) diagnosis after Helicobacter pylori eradication and differentiation from patchy redness (PR) remains challenging. We developed a novel automated analysis system for microvascular blood flow rat…
View article: Clinicopathological Characteristics With the Status of Mismatch Repair Deficient Invasive Colorectal Cancer With Spontaneous Regression
Clinicopathological Characteristics With the Status of Mismatch Repair Deficient Invasive Colorectal Cancer With Spontaneous Regression Open
Spontaneous regression of endoscopically invasive colorectal cancer (CRC) after biopsy has been rarely reported. We report three cases of endoscopically invasive CRC with spontaneous regression after biopsy and a review of the literature r…
View article: The effects of different traction devices on colorectal endoscopic submucosal dissection outcomes
The effects of different traction devices on colorectal endoscopic submucosal dissection outcomes Open
Background: Endoscopic submucosal dissection (ESD) enables en bloc resection of large colorectal lesions, but it remains challenging due to thin walls and poor operability. Traction devices like SureClip traction band (SCTB, Micro-tech) an…
View article: Developing Low-Viscosity Lubricants to Maintain Lubricity between Overtube and Enteroscope for Improved Maneuverability during Single-Balloon Enteroscopy
Developing Low-Viscosity Lubricants to Maintain Lubricity between Overtube and Enteroscope for Improved Maneuverability during Single-Balloon Enteroscopy Open
During enteroscopy, the hydrophilic coating on the inner surface of the overtube (OT) reduces the dynamic friction coefficient (DFC) between the endoscopic shaft (ES) and OT, allowing smooth insertion of the ES. However, endoscopists often…
View article: Kyoto Classification-Based Predictive Factors Associated with the Development of Gastric Cancer After Helicobacter pylori Eradication: A Prospective Multicenter Observational Study
Kyoto Classification-Based Predictive Factors Associated with the Development of Gastric Cancer After Helicobacter pylori Eradication: A Prospective Multicenter Observational Study Open
Background/Objectives: This study aimed to identify specific endoscopic findings associated with the development of GC following successful H. pylori eradication. Methods: This prospective multicenter observational study included patients …
View article: A Multicenter Pivotal Study on the Artificial Intelligence System for Neoplastic Lesions Detection in Upper Gastrointestinal Endoscopy
A Multicenter Pivotal Study on the Artificial Intelligence System for Neoplastic Lesions Detection in Upper Gastrointestinal Endoscopy Open
Objectives This pivotal study aimed to evaluate the performance of the CAD‐EYE prototype in identifying esophageal squamous cell carcinoma (ESCC) and gastric neoplasm (GN) for regulatory approval of the Pharmaceuticals and Medical Devices …
View article: Differences in complications between colonoscopy and esophagogastroduodenoscopy in Japan using large-scale health insurance claims data
Differences in complications between colonoscopy and esophagogastroduodenoscopy in Japan using large-scale health insurance claims data Open
Analyses of colonoscopy (CS) and esophagogastroduodenoscopy (EGD) complications is crucial for further promoting use of endoscopy. This study analyzed rates of severe complications of CS compared with those of EGD using big data. As a stud…
View article: Submucosal fibrosis in large colorectal serrated lesions in cases receiving endoscopic submucosal dissection
Submucosal fibrosis in large colorectal serrated lesions in cases receiving endoscopic submucosal dissection Open
Background: Submucosal fibrosis is a known risk factor for adverse outcomes in colorectal endoscopic submucosal dissection (ESD). However, evidence regarding the presence and impact of fibrosis in colorectal serrated lesions (CSLs) remains…
View article: Pure Well-differentiated Adenocarcinoma as a Safe Factor for Lymph Node Metastasis and Recurrence of T1 Colorectal Cancer
Pure Well-differentiated Adenocarcinoma as a Safe Factor for Lymph Node Metastasis and Recurrence of T1 Colorectal Cancer Open
PWDA can predict safety against LNM and recurrence in patients with T1 colorectal cancer.
View article: An Additional 30-s Observation of the Right-Sided Colon Using a Novel Endoscopic System with Texture and Color Enhancement Imaging Decreases Polyp Miss Rates: A Multicenter Study
An Additional 30-s Observation of the Right-Sided Colon Using a Novel Endoscopic System with Texture and Color Enhancement Imaging Decreases Polyp Miss Rates: A Multicenter Study Open
Background/Objectives: White light imaging (WLI) of colonoscopy has a 26% adenoma miss rate. We aimed to evaluate the effectiveness of an additional 30 s (Add-30s) observation of the right-sided colon using a novel system (EVIS X1; Olympus…
View article: Risk of Metastasis and Local Residual Cancer After Non‐Curative Endoscopic Submucosal Dissection for Esophageal Cancer
Risk of Metastasis and Local Residual Cancer After Non‐Curative Endoscopic Submucosal Dissection for Esophageal Cancer Open
Background Endoscopic submucosal dissection (ESD) is widely used to treat early‐stage esophageal squamous cell carcinoma (SCC). However, the risk of recurrence in non‐curative cases remains uncertain. This study aimed to elucidate the risk…
View article: Management of Adverse Events Related to Endoscopic Resection for Superficial Non-Ampullary Duodenal Epithelial Tumors
Management of Adverse Events Related to Endoscopic Resection for Superficial Non-Ampullary Duodenal Epithelial Tumors Open
Background: Endoscopic resection (ER) is a minimally invasive alternative to surgical resection for superficial non-ampullary duodenal epithelial tumors (SNADETs); however, it carries a high risk of adverse events (AEs) due to the thin duo…
View article: Efficacy of Gel Immersion Tumor Characterization for Colorectal Lesions: A Pilot Study
Efficacy of Gel Immersion Tumor Characterization for Colorectal Lesions: A Pilot Study Open
Background Gel immersion endoscopy is a novel method that uses gel to enhance the visual field. This study aimed to analyze the efficacy of magnified endoscopy under gel immersion for optimal visualization and characterization of colorecta…
View article: Gel Immersion Endoscopic Submucosal Dissection Using a Scissor‐type Knife for Superficial Non‐ampullary Duodenal Epithelial Tumors
Gel Immersion Endoscopic Submucosal Dissection Using a Scissor‐type Knife for Superficial Non‐ampullary Duodenal Epithelial Tumors Open
Objectives This study aimed to compare the short‐term therapeutic outcomes between conventional endoscopic submucosal dissection (C‐ESD) and gel immersion ESD (GI‐ESD) for superficial non‐ampullary duodenal epithelial tumors (SNADETs). Met…
View article: Endoscopic Submucosal Dissection Versus Laparoscopic and Endoscopic Cooperative Surgery for Superficial Duodenal Epithelial Tumors: A Multicenter Retrospective Study
Endoscopic Submucosal Dissection Versus Laparoscopic and Endoscopic Cooperative Surgery for Superficial Duodenal Epithelial Tumors: A Multicenter Retrospective Study Open
Aims This study aimed to compare the clinicopathological features and short‐term outcomes of endoscopic submucosal dissection (ESD) and laparoscopic and endoscopic cooperative surgery (LECS) for superficial duodenal epithelial tumors (SDET…
View article: Improvement of Colonoscopic Image Quality Using a New LED Endoscopic System with Specialized Noise Reduction
Improvement of Colonoscopic Image Quality Using a New LED Endoscopic System with Specialized Noise Reduction Open
Background/Objectives: A new LED endoscopy system featuring advanced noise-reduction technology, the EP-8000 with the EC-860ZP colonoscope (Fujifilm), was introduced in 2024. We evaluated the improvements in colonoscopic image quality of t…
View article: Usefulness of Endoscopic Mucosal Resection Using an Over‐the‐Scope Clip for Duodenal Neuroendocrine Tumors: A Multicenter Retrospective Comparative Study
Usefulness of Endoscopic Mucosal Resection Using an Over‐the‐Scope Clip for Duodenal Neuroendocrine Tumors: A Multicenter Retrospective Comparative Study Open
Background and Aim Resection of non‐ampullary duodenal neuroendocrine tumors presents technical challenges. This study investigated the efficacy and safety of endoscopic mucosal resection using an over‐the‐scope clip compared to endoscopic…
View article: The Comparison Between Low‐ and High‐Concentration Injection Solution Ability for Colorectal Endoscopic Submucosal Dissection
The Comparison Between Low‐ and High‐Concentration Injection Solution Ability for Colorectal Endoscopic Submucosal Dissection Open
Background and Aim Injection solution is important for achieving submucosal elevation in endoscopic submucosal dissection (ESD) and various viscous solutions categorized as low‐concentration injection solution (LCS) or high‐concentration i…
View article: Peroral Endoscopic Tumor Resection for Esophageal Leiomyoma with Accumulation of Fluorine-18-Fluorodeoxyglucose: A Case Report
Peroral Endoscopic Tumor Resection for Esophageal Leiomyoma with Accumulation of Fluorine-18-Fluorodeoxyglucose: A Case Report Open
Introduction: Esophageal leiomyomas are relatively common benign esophageal submucosal tumors (SMTs). Generally, benign tumors do not accumulate fluorine-18-fluorodeoxyglucose (FDG), but it is not rare for FDG to accumulate in uterine, duo…
View article: Endoscopic resection with one-port placement for duodenal neuroendocrine tumor: toward more minimally invasive endoscopic management
Endoscopic resection with one-port placement for duodenal neuroendocrine tumor: toward more minimally invasive endoscopic management Open
View article: Prognostic value of liver metastasis in patients with esophageal squamous cell carcinoma treated with nivolumab
Prognostic value of liver metastasis in patients with esophageal squamous cell carcinoma treated with nivolumab Open
Nivolumab has been approved for unresectable recurrent advanced esophageal cancer. The present study aimed to provide real-world data on diverse patient profiles, including the elderly and those with poor performance status, while explorin…
View article: Neoadjuvant Chemotherapy Followed by Laparoscopic and Endoscopic Cooperative Surgery for Locally Advanced Duodenal Gastrointestinal Stromal Tumor: A Case Report
Neoadjuvant Chemotherapy Followed by Laparoscopic and Endoscopic Cooperative Surgery for Locally Advanced Duodenal Gastrointestinal Stromal Tumor: A Case Report Open
Neoadjuvant imatinib effectively downsized a locally advanced D-GIST, enabling safe, minimally invasive resection via D-LECS. This case highlights the potential of NAC and D-LECS as a less invasive alternative to PD in anatomically challen…
View article: Clinical significance of cachexia index determined by bioelectrical impedance analysis in patients with gastrointestinal cancer
Clinical significance of cachexia index determined by bioelectrical impedance analysis in patients with gastrointestinal cancer Open
Cancer cachexia is a complex disorder characterized by skeletal muscle loss, which may influence the prognosis of patients with cancer. The cachexia index (CXI) is a new index for cachexia. The present study aimed to assess whether the CXI…
View article: Prevalence of gastric cancer following colorectal endoscopic submucosal dissection for lesions more than 20 mm: A retrospective analysis
Prevalence of gastric cancer following colorectal endoscopic submucosal dissection for lesions more than 20 mm: A retrospective analysis Open
Objectives Colorectal endoscopic submucosal dissection (ESD) for large tumors is spreading worldwide. Gastric cancer (GC) sometimes occurs after colorectal ESD. However, its status including frequency and risk factors have not been examine…
View article: High‐Performance Dedicated Snares with Tip Attachments can Overcome Current Disadvantages in Cold Snare Polypectomy
High‐Performance Dedicated Snares with Tip Attachments can Overcome Current Disadvantages in Cold Snare Polypectomy Open
Cold snare polypectomy (CSP) has the disadvantage of a lower histopathological complete resection rate (HCRR) because blunt resection using CSP‐dedicated snares (DSs) causes mucosal retraction into the sheath during capture/resection. In t…
View article: Additional 30-second observation of the right-sided colon for missed polyp detection with linked color imaging compared with narrow band imaging
Additional 30-second observation of the right-sided colon for missed polyp detection with linked color imaging compared with narrow band imaging Open
Background and study aims We previously demonstrated the efficacy of an additional-30-seconds (Add-30s) observation with linked color imaging (LCI) or narrow band imaging (NBI) of the cecum and ascending colon (right-sided colon) after whi…
View article: Effect of texture and color enhancement imaging on the visibility of gastric tumors
Effect of texture and color enhancement imaging on the visibility of gastric tumors Open
Texture and color enhancement imaging (TXI) may improve the visibility of gastric tumors and allow their early detection. However, few reports have examined the utility of TXI. Between June 2021 and October 2022, 56 gastric tumors in 51 pa…
View article: Endoscopic detection and diagnosis of gastric cancer using image‐enhanced endoscopy: A systematic review and meta‐analysis
Endoscopic detection and diagnosis of gastric cancer using image‐enhanced endoscopy: A systematic review and meta‐analysis Open
Objectives We aimed to conduct a systematic review and meta‐analysis to assess the value of image‐enhanced endoscopy including blue laser imaging (BLI), linked color imaging, narrow‐band imaging (NBI), and texture and color enhancement ima…
View article: Non-polypoid Colorectal Lesions Detection and False Positive Detection by Artificial Intelligence under Blue Laser Imaging and Linked Color Imaging
Non-polypoid Colorectal Lesions Detection and False Positive Detection by Artificial Intelligence under Blue Laser Imaging and Linked Color Imaging Open
AI finetuned by appropriate LS detected non-reddish and non-polypoid polyps under LCI.
View article: Urolithin A-mediated augmentation of intestinal barrier function through elevated secretory mucin synthesis
Urolithin A-mediated augmentation of intestinal barrier function through elevated secretory mucin synthesis Open