Óscar Murillo
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View article: Efficacy, safety, and population pharmacokinetics of a single 1500mg dose of dalbavancin for short-term therapy in patients with chronic prosthetic joint infections
Efficacy, safety, and population pharmacokinetics of a single 1500mg dose of dalbavancin for short-term therapy in patients with chronic prosthetic joint infections Open
The efficacy, safety, and population pharmacokinetics of a single 1,500 mg dose of dalbavancin as a sequencing treatment for Gram-positive chronic prosthetic joint infections (CPJIs) have not been described. We present an observational, re…
View article: Exploring the Microbiome of Diabetic Foot Ulcers: A Focus on Cases with a Clinical Worse Outcome
Exploring the Microbiome of Diabetic Foot Ulcers: A Focus on Cases with a Clinical Worse Outcome Open
Background/Objectives: We evaluated the diabetic foot ulcer (DFU) microbiome in clinical situations identified as risk factors for a worse outcome and explored the roles of the most abundant microorganisms. Methods: A prospective multicent…
View article: Bilayer sol-gel system for local prevention in prosthetic joint infections and osteointegration improvement
Bilayer sol-gel system for local prevention in prosthetic joint infections and osteointegration improvement Open
Prosthetic joint infection (PJI) is one of the most severe complications associated with arthroplasties. Here we evaluate a bilayer coating system designed for both PJI prevention and osteoinduction. The outer layer is loaded with levoflox…
View article: Collateral susceptibility-guided alternation of ceftolozane/tazobactam with imipenem prevents resistance development in XDR Pseudomonas aeruginosa biofilms
Collateral susceptibility-guided alternation of ceftolozane/tazobactam with imipenem prevents resistance development in XDR Pseudomonas aeruginosa biofilms Open
Collateral susceptibility-guided alternation of ceftolozane/tazobactam with imipenem effectively prevented the selection of resistant mutants and thus could be a potential therapeutic strategy for the treatment of P. aeruginosa XDR …
View article: Appropriate Duration of Antimicrobial Treatment for Prosthetic Joint Infections: A Narrative Review
Appropriate Duration of Antimicrobial Treatment for Prosthetic Joint Infections: A Narrative Review Open
Prosthetic joint infections are considered difficult to treat they needing aggressive surgery and long antimicrobial treatments. However, the exact duration of these therapies has been established empirically. In the last years, several st…
View article: Executive summary: Guidelines for the diagnosis and treatment of septic arthritis in adults and children, developed by the GEIO (SEIMC), SEIP and SECOT
Executive summary: Guidelines for the diagnosis and treatment of septic arthritis in adults and children, developed by the GEIO (SEIMC), SEIP and SECOT Open
View article: The Epidemiology of Antibiotic-Related Adverse Events in the Treatment of Diabetic Foot Infections: A Narrative Review of the Literature
The Epidemiology of Antibiotic-Related Adverse Events in the Treatment of Diabetic Foot Infections: A Narrative Review of the Literature Open
The use of antibiotics for the treatment of diabetic foot infections (DFIs) over an extended period of time has been shown to be associated with adverse events (AEs), whereas interactions with concomitant patient medications must also be c…
View article: Cutibacterium spp. Infections after Instrumented Spine Surgery Have a Good Prognosis Regardless of Rifampin Use: A Cross-Sectional Study
Cutibacterium spp. Infections after Instrumented Spine Surgery Have a Good Prognosis Regardless of Rifampin Use: A Cross-Sectional Study Open
Infection after spinal instrumentation (IASI) by Cutibacterium spp. is being more frequently reported. The aim of this study was to analyse the incidence, risk factors, clinical characteristics, and outcome of a Cutibacterium spp. IASI (CG…
View article: <i>Mycobacterium fortuitum</i> osteomyelitis of the cuboid bone treated with CERAMENT G and V: a case report
<i>Mycobacterium fortuitum</i> osteomyelitis of the cuboid bone treated with CERAMENT G and V: a case report Open
We present the rare case of a 61-year-old female with Mycobacterium fortuitum osteomyelitis of the cuboid bone following penetrating plantar trauma. The patient underwent a single-stage surgery for the condition, including lesion debrideme…
View article: Análisis de la evolucion tras el alta de urgencias en pacientes con neumonía por COVID-19 en función del recurso sanitario utilizado para el seguimiento: estudio RESALSEVID
Análisis de la evolucion tras el alta de urgencias en pacientes con neumonía por COVID-19 en función del recurso sanitario utilizado para el seguimiento: estudio RESALSEVID Open
View article: Corrigendum to “Prognosis of unexpected positive intraoperative cultures in arthroplasty revision: A large multicenter cohort” [Journal of Infection 83 (2021) 542–549]
Corrigendum to “Prognosis of unexpected positive intraoperative cultures in arthroplasty revision: A large multicenter cohort” [Journal of Infection 83 (2021) 542–549] Open
View article: Impact of COVID-19 disease on platelet reactivity and association with inflammatory parameters
Impact of COVID-19 disease on platelet reactivity and association with inflammatory parameters Open
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the coronavirus disease 2019 (COVID-19) pandemic. Aside from the pulmonary manifestations, COVID-19 is associated with increased ri…
View article: Prosthetic Shoulder Joint Infection by Cutibacterium acnes: Does Rifampin Improve Prognosis? A Retrospective, Multicenter, Observational Study
Prosthetic Shoulder Joint Infection by Cutibacterium acnes: Does Rifampin Improve Prognosis? A Retrospective, Multicenter, Observational Study Open
This retrospective, multicenter observational study aimed to describe the outcomes of surgical and medical treatment of C. acnes-related prosthetic joint infection (PJI) and the potential benefit of rifampin-based therapies. Patients with …
View article: Risk Factors of Daptomycin-Induced Eosinophilic Pneumonia in a Population with Osteoarticular Infection
Risk Factors of Daptomycin-Induced Eosinophilic Pneumonia in a Population with Osteoarticular Infection Open
Background: Daptomycin-induced eosinophilic pneumonia (DEP) is a rare but severe adverse effect and the risk factors are unknown. The aim of this study was to determine risk factors for DEP. Methods: A retrospective cohort study was perfor…
View article: Tratamientos farmacológicos de los pacientes con COVID19: interacciones e indicaciones
Tratamientos farmacológicos de los pacientes con COVID19: interacciones e indicaciones Open
View article: Suppressive antibiotic therapy in prosthetic joint infections: a multicentre cohort study
Suppressive antibiotic therapy in prosthetic joint infections: a multicentre cohort study Open
View article: Timing of implant-removal in late acute periprosthetic joint infection: A multicenter observational study
Timing of implant-removal in late acute periprosthetic joint infection: A multicenter observational study Open
View article: Impact of β-Lactam and Daptomycin Combination Therapy on Clinical Outcomes in Methicillin-susceptible Staphylococcus aureus Bacteremia: A Propensity Score–matched Analysis
Impact of β-Lactam and Daptomycin Combination Therapy on Clinical Outcomes in Methicillin-susceptible Staphylococcus aureus Bacteremia: A Propensity Score–matched Analysis Open
Background Mortality rates from Staphylococcus aureus bacteremia are high and have only modestly improved in recent decades. We compared the efficacies of a β-lactam in combination with daptomycin (BL/D-C) and β-lactam monotherapy (BL-M) i…
View article: CLINICAL OUTCOME AND RISK FACTORS FOR FAILURE IN LATE ACUTE PROSTHETIC JOINT INFECTIONS TREATED WITH DEBRIDEMENT AND IMPLANT RETENTION
CLINICAL OUTCOME AND RISK FACTORS FOR FAILURE IN LATE ACUTE PROSTHETIC JOINT INFECTIONS TREATED WITH DEBRIDEMENT AND IMPLANT RETENTION Open
View article: Clinical outcome and risk factors for failure in late acute prosthetic joint infections treated with debridement and implant retention
Clinical outcome and risk factors for failure in late acute prosthetic joint infections treated with debridement and implant retention Open
View article: Candida periprosthetic joint infection: A rare and difficult-to-treat infection
Candida periprosthetic joint infection: A rare and difficult-to-treat infection Open
View article: Late Acute Periprosthetic Joint Infections; When Should the Implant Be Removed?
Late Acute Periprosthetic Joint Infections; When Should the Implant Be Removed? Open
View article: The Not-So-Good Prognosis of Streptococcal Periprosthetic Joint Infection Managed by Implant Retention: The Results of a Large Multicenter Study
The Not-So-Good Prognosis of Streptococcal Periprosthetic Joint Infection Managed by Implant Retention: The Results of a Large Multicenter Study Open
This is the largest series to our knowledge of streptococcal PJI managed by DAIR, showing a worse prognosis than previously reported. The beneficial effects of exchanging the removable components and of β-lactams are confirmed and maybe al…
View article: Pyogenic arthritis of native joints due to Bacteroides fragilis
Pyogenic arthritis of native joints due to Bacteroides fragilis Open
Pyogenic arthritis of native joints due to Bacteroides fragilis seems to be an infrequent disease. We analyzed the cases diagnosed in a tertiary hospital during a 22-year period and reviewed the literature to summarize the experience with …
View article: Time trends in the aetiology of prosthetic joint infections: a multicentre cohort study
Time trends in the aetiology of prosthetic joint infections: a multicentre cohort study Open
View article: <i>Editorial Commentary</i>: Pyogenic Vertebral Osteomyelitis and Antimicrobial Therapy: It's Not Just the Length, but Also the Choice
<i>Editorial Commentary</i>: Pyogenic Vertebral Osteomyelitis and Antimicrobial Therapy: It's Not Just the Length, but Also the Choice Open
View article: Osteoarticular infection caused by MDR<i>Pseudomonas aeruginosa</i>: the benefits of combination therapy with colistin plus β-lactams
Osteoarticular infection caused by MDR<i>Pseudomonas aeruginosa</i>: the benefits of combination therapy with colistin plus β-lactams Open
We suggest that the BL/colistin combination is an optimized therapy for OI caused by MDR P. aeruginosa, together with an appropriate surgical treatment.