Óscar Rosas‐Carrasco
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View article: Vitamin D and cognition: Demographic disparities in memory recall and word intrusion in a multiethnic cohort
Vitamin D and cognition: Demographic disparities in memory recall and word intrusion in a multiethnic cohort Open
Background Vitamin D3 is essential for calcium metabolism and exerts pleiotropic effects, including neuroprotective activities in cognition. Its insufficiency has been linked to dementia, Alzheimer's disease, and cognitive impairments. The…
View article: Undernutrition risk and obesity increase the risk of osteosarcopenia in Mexican adults aged 50 and over: a prospective cohort study
Undernutrition risk and obesity increase the risk of osteosarcopenia in Mexican adults aged 50 and over: a prospective cohort study Open
Introduction Undernutrition risk in adults is a common but undiagnosed condition, while obesity is highly prevalent in this population. Osteosarcopenia is the coexistence of sarcopenia and osteopenia/osteoporosis and is related to higher m…
View article: Challenges and Opportunities for Adult Vaccine Coverage: Insights for Healthcare Professionals Focusing on Herpes Zoster in Mexico
Challenges and Opportunities for Adult Vaccine Coverage: Insights for Healthcare Professionals Focusing on Herpes Zoster in Mexico Open
Herpes zoster (HZ) is a common disease in older adults and immunocompromised patients, and is frequently associated with long-term complications that impact quality of life. Fortunately, more than one vaccine against HZ is now available in…
View article: Synergistic Effect between the APOE ε4 Allele with Genetic Variants of GSK3B and MAPT: Differential Profile between Refractory Epilepsy and Alzheimer Disease
Synergistic Effect between the APOE ε4 Allele with Genetic Variants of GSK3B and MAPT: Differential Profile between Refractory Epilepsy and Alzheimer Disease Open
Temporal Lobe Epilepsy (TLE) is a chronic neurological disorder characterized by recurrent focal seizures originating in the temporal lobe. Despite the variety of antiseizure drugs currently available to treat TLE, about 30% of cases conti…
View article: Association between the risk of malnutrition and sarcopenia at 4.2 years of follow-up in community-dwelling older adults
Association between the risk of malnutrition and sarcopenia at 4.2 years of follow-up in community-dwelling older adults Open
Introduction Currently, there is only scarce evidence of a causal association between risk of malnutrition (RM) by the mini-nutritional assessment (MNA) and the incidence of sarcopenia. This study was designed to assess such an association…
View article: Incidence of the Risk of Malnutrition and Excess Fat Mass, and Gait Speed as Independent Associated Factors in Community-Dwelling Older Adults
Incidence of the Risk of Malnutrition and Excess Fat Mass, and Gait Speed as Independent Associated Factors in Community-Dwelling Older Adults Open
Background and aims: Only one cohort study exists on the incidence of the risk of malnutrition (RM) in older adults, though numerous cross-sectional reports, identified several risk factors associated with the prevalence and incidence of t…
View article: Effectiveness of an online multicomponent physical exercise intervention on the physical performance of community-dwelling older adults: A randomized controlled trial
Effectiveness of an online multicomponent physical exercise intervention on the physical performance of community-dwelling older adults: A randomized controlled trial Open
This study aimed to assess the effectiveness of an online multicomponent physical exercise intervention (MPE) on the physical performance (PP) of older adults. A randomized controlled trial was conducted, with 110 participants assigned to …
View article: Incidence of the Risk of Malnutrition and Excess Fat Mass, Low Total Lean Tissue, and Gait Speed as Independent Associated Factors in Community-Dwelling Older Adults
Incidence of the Risk of Malnutrition and Excess Fat Mass, Low Total Lean Tissue, and Gait Speed as Independent Associated Factors in Community-Dwelling Older Adults Open
Background and aims: Only one cohort study exists on the incidence of the risk of malnutrition (RM) in older adults, though numerous cross-sectional –and that cohort research– have reported several risk factors associated with the prevalen…
View article: Development and validation of a Sarcopenia Geriatric Scale (SARCO-GS): a new short scale for the screening of sarcopenia
Development and validation of a Sarcopenia Geriatric Scale (SARCO-GS): a new short scale for the screening of sarcopenia Open
Introduction Sarcopenia is a highly prevalent disease associated with adverse outcomes such as falls, disability, and death. The current international consensuses agree that muscle strength, muscle mass, and gait speed must be included in …
View article: Low muscle strength and low phase angle predicts greater risk to mortality than severity scales (APACHE, SOFA, and CURB-65) in adults hospitalized for SARS-CoV-2 pneumonia
Low muscle strength and low phase angle predicts greater risk to mortality than severity scales (APACHE, SOFA, and CURB-65) in adults hospitalized for SARS-CoV-2 pneumonia Open
Introduction The acute physiology and chronic health evaluation (APACHE), sepsis-related organ failure assessment (SOFA), score for pneumonia severity (CURB-65) scales, a low phase angle (PA) and low muscle strength (MS) have demonstrated …
View article: Identification of Probable sarcopenia based on SARC-F and SARC-CalF in older adults from a low-resource setting
Identification of Probable sarcopenia based on SARC-F and SARC-CalF in older adults from a low-resource setting Open
We found that one out of three of the population had probable sarcopenia. SARC-Calf showed superior but still low sensitivity than SARC-F, while both had moderate specificity and thus may be useful for ruling out the disease in clinical pr…
View article: Low Physical Performance is Associated with a Poor Health-Related Quality of Life (HRQOL) in Community-Dwelling Older Mexicans”
Low Physical Performance is Associated with a Poor Health-Related Quality of Life (HRQOL) in Community-Dwelling Older Mexicans” Open
Objective Identify the association between low physical performance and quality of life in older adults. MethodsCross-sectional analysis of the FraDySMex cohort study (Frailty, Daphnia and Sarcopenia in Mexican Adults). The physical perfor…
View article: Association between physical activity and physical and functional performance in non-institutionalized Mexican older adults: a cohort study
Association between physical activity and physical and functional performance in non-institutionalized Mexican older adults: a cohort study Open
Background Aging is an independent risk factor for deterioration in functional capacity. Some studies have reported that physical activity (PA) improves functional capacity and physical performance among older adults (OA). Thus the objecti…
View article: SORL1 Polymorphisms in Mexican Patients with Alzheimer’s Disease
SORL1 Polymorphisms in Mexican Patients with Alzheimer’s Disease Open
The present study evaluated the risk effect of 12 Single Nucleotide Polymorphisms in the SORL1 gene in the Mexican population using Late-Onset Alzheimer’s Disease (LOAD) and control subjects. Considering APOE as the strongest genetic risk …
View article: The Association of Osteosarcopenia With Functional Disability in Community-Dwelling Mexican Adults 50 and Older
The Association of Osteosarcopenia With Functional Disability in Community-Dwelling Mexican Adults 50 and Older Open
Background: Osteosarcopenia (OS) has recently been described as a predictor of negative outcomes in older adults. However, this alteration in body composition has not been widely studied. In Mexico and Latin America, no information is avai…
View article: Phase Angle Cut-Off Points and Their Association With Sarcopenia and Frailty in Adults of 50–64 Years Old and Older Adults in Mexico City
Phase Angle Cut-Off Points and Their Association With Sarcopenia and Frailty in Adults of 50–64 Years Old and Older Adults in Mexico City Open
Background: In recent studies, the usefulness of the phase angle (PA) to assess geriatric conditions such as sarcopenia and frailty has been evaluated. However, there are no useful cut-off points for clinical research and/or practice. Obje…
View article: Low‐Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and Oxidative Stress and Increasing GDF‐11
Low‐Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and Oxidative Stress and Increasing GDF‐11 Open
The loss of skeletal muscle mass and strength is known as sarcopenia; it is characterized as a progressive and generalized muscle disorder associated with aging. This deterioration can seriously compromise the elderly’s health and reduce t…
View article: Long-Term Moderate Exercise Combined with Metformin Treatment Induces an Hormetic Response That Prevents Strength and Muscle Mass Loss in Old Female Wistar Rats
Long-Term Moderate Exercise Combined with Metformin Treatment Induces an Hormetic Response That Prevents Strength and Muscle Mass Loss in Old Female Wistar Rats Open
Sarcopenia is a syndrome characterized by a progressive and generalized skeletal muscle mass and strength loss, as well as a poor physical performance, which as strongly been associated with aging. Sedentary lifestyle in the elderly contri…
View article: Sarcopenia, But Not Sarcopenic Obesity, is Associated with Clinically Significant Depressive Symptoms in Older Mexican Adults
Sarcopenia, But Not Sarcopenic Obesity, is Associated with Clinically Significant Depressive Symptoms in Older Mexican Adults Open
Background: Sarcopenia and obesity have a high prevalence in Mexico. Evidence suggests that there is an association between these disorders and clinically significant depressive symptoms. Objective: The aim of the study is to provide the r…
View article: SLEEP DISORDERS ARE ASSOCIATED WITH THE PRESENCE OF FRAILTY IN OLDER ADULTS
SLEEP DISORDERS ARE ASSOCIATED WITH THE PRESENCE OF FRAILTY IN OLDER ADULTS Open
Frailty is a geriatric syndrome characterized by reduced functional reserve, which results in adverse health outcomes such as disability and premature death. Meanwhile, sleep disorders are frequent in the elderly, and their presence is ass…
View article: OSTEOSARCOPENIC OBESITY: FREQUENCY AND ITS RELATION WITH FRAILTY AND PHYSICAL PERFORMANCE
OSTEOSARCOPENIC OBESITY: FREQUENCY AND ITS RELATION WITH FRAILTY AND PHYSICAL PERFORMANCE Open
Design: Cross-sectional analysis of a prospective cohort.
View article: Sociodemographic and Clinical Characteristics of Centenarians in Mexico City
Sociodemographic and Clinical Characteristics of Centenarians in Mexico City Open
Background. There is little evidence about the demography and health status of adults aged 100 years and over in Latin America and there are no studies in Mexico. Objectives. To describe the demographic characteristics and health status of…
View article: Psychometric properties of the Satisfaction with Life Scale (SWLS): secondary analysis of the Mexican Health and Aging Study
Psychometric properties of the Satisfaction with Life Scale (SWLS): secondary analysis of the Mexican Health and Aging Study Open
Results show good internal consistency and construct validity of the SWLS. These results are comparable with results from previous studies. Meeting the study's objective to validate the scale, the results show that the Spanish version of t…