Osnat Shtraichman
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View article: Single versus double lung transplantation outcomes in artificial stone silicosis: a single-centre retrospective cohort study
Single versus double lung transplantation outcomes in artificial stone silicosis: a single-centre retrospective cohort study Open
Background Silicosis, caused by inhaling crystalline silica, is a growing global health concern exacerbated by the increased use of artificial stone. In end-stage silicosis, lung transplantation may be the only available treatment. While d…
View article: Native lung aspergilloma after single lung transplantation—a case series
Native lung aspergilloma after single lung transplantation—a case series Open
This case series emphasizes the importance of a high index of suspicion of aspergilloma developing in the native lung after an SLT. Although this is a significantly high-risk group due to their immunodeficiency, their overall prognosis in …
View article: Lung transplantation for pulmonary chronic graft-versus-host disease: a missed opportunity?
Lung transplantation for pulmonary chronic graft-versus-host disease: a missed opportunity? Open
Chronic graft-versus-host disease is a common complication after allogeneic hematopoietic stem cell transplantation, with pulmonary chronic graft-versus-host disease (PcGvHD) particularly associated with a dismal prognosis. Lung transplant…
View article: Pretransplant NT‐proBNP levels are associated with mortality among lung transplant recipients
Pretransplant NT‐proBNP levels are associated with mortality among lung transplant recipients Open
The prognostic significance of pretransplant N‐terminal pro‐brain (B)‐type natriuretic peptide (NT‐proBNP) level has not been investigated in lung transplant recipients. The electronic files of 173 patients with chronic lung disease who un…
View article: A single center Israeli experience in pregnancy post lung transplantation: Feasibility of successful two or more full‐term pregnancies in individual lung transplant recipients
A single center Israeli experience in pregnancy post lung transplantation: Feasibility of successful two or more full‐term pregnancies in individual lung transplant recipients Open
Introduction Female lung transplant recipients (LTRs) of reproductive age are increasingly considering pregnancy due to advances in post‐transplant management and improved survival. We report our experience with pregnancy in LTRs, with an …
View article: Immunogenicity of a Third Dose of BNT162b2 Vaccine among Lung Transplant Recipients—A Prospective Cohort Study
Immunogenicity of a Third Dose of BNT162b2 Vaccine among Lung Transplant Recipients—A Prospective Cohort Study Open
Two doses of mRNA SARS-CoV-2 vaccines elicit an attenuated humoral immune response among immunocompromised patients. Our study aimed to assess the immunogenicity of a third dose of the BNT162b2 vaccine among lung transplant recipients (LTR…
View article: Humoral response among patients with interstitial lung disease vaccinated with the BNT162b2 SARS-Cov-2 vaccine: a prospective cohort study
Humoral response among patients with interstitial lung disease vaccinated with the BNT162b2 SARS-Cov-2 vaccine: a prospective cohort study Open
Background Patients with interstitial lung disease (ILD) are at high risk of severe COVID-19 infection. Additionally, their anti-inflammatory and antifibrotic treatment may cause immunosuppression. Nevertheless, their ability to mount an a…
View article: Prognostic Significance of the N-Terminal Pro-B-Type Natriuretic Peptide in Lung Transplant Candidates on the Waiting List
Prognostic Significance of the N-Terminal Pro-B-Type Natriuretic Peptide in Lung Transplant Candidates on the Waiting List Open
We investigated the prognostic significance of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in lung transplant candidates, in a retrospective single-center study. Data regarding various baseline characteristics and all-cause morta…
View article: Humoral Response among Patients with Interstitial Lung Disease Vaccinated with the BNT162b2 SARS-Cov-2 vaccine - A Prospective Cohort Study
Humoral Response among Patients with Interstitial Lung Disease Vaccinated with the BNT162b2 SARS-Cov-2 vaccine - A Prospective Cohort Study Open
Background: Patients with interstitial lung disease (ILD) are at high risk of severe COVID-19 infection. Additionally, their anti-inflammatory and antifibrotic treatment may cause immunosuppression. Nevertheless, their ability to mount an …
View article: Characteristics of lung cancer in idiopathic pulmonary fibrosis with single lung transplant versus non-transplanted patients: a retrospective observational study
Characteristics of lung cancer in idiopathic pulmonary fibrosis with single lung transplant versus non-transplanted patients: a retrospective observational study Open
Background Patients with idiopathic pulmonary fibrosis (IPF) have significantly higher incidence of lung cancer (LC) relative to the general population. There is a further increase in LC incidence in patients with IPF subsequent to lung tr…
View article: Efficacy and Safety of Mepolizumab in a Real-World Cohort of Patients with Severe Eosinophilic Asthma
Efficacy and Safety of Mepolizumab in a Real-World Cohort of Patients with Severe Eosinophilic Asthma Open
Background: The interleukin 5 (IL-5) pathway is an important component in the pathophysiology of severe eosinophilic asthma. Mepolizumab is a monoclonal antibody that targets the IL-5 pathw...
View article: Stereotactic body radiation therapy (SBRT) for the treatment of primary lung cancer in recipients of lung transplant
Stereotactic body radiation therapy (SBRT) for the treatment of primary lung cancer in recipients of lung transplant Open
Background Lung transplantation is a life-saving treatment for patients with end stage lung disease. There may be a higher incidence of lung cancer in lung transplant recipients, and these cancers tend to be diagnosed at a more advanced st…
View article: Safety and Allograft Function Post Native Lung Pneumonectomy, A Single Lung Transplant Center Experience
Safety and Allograft Function Post Native Lung Pneumonectomy, A Single Lung Transplant Center Experience Open
Single lung transplantation is a valuable treatment option for end stage lung disease cases of which bilateral lung transplantation is not necessarily indicated. The main disadvantage of single lung transplantation is complications related…
View article: Malignancy after lung transplantation
Malignancy after lung transplantation Open
Lung transplantation is an established therapeutic option for selected patients with advanced lung diseases. As early outcomes after lung transplantation have improved, chronic medical illnesses have emerged as significant obstacles to lon…
View article: Non-tuberculous, adenosine deaminase-positive lymphocytic pleural effusion: Consider immunoglobulin G4-related disease.
Non-tuberculous, adenosine deaminase-positive lymphocytic pleural effusion: Consider immunoglobulin G4-related disease. Open
IgG4-RD may cause an ADA-positive, lymphocytic exudate with a high protein concentration, characteristics resembling tuberculous effusion. Thoracic lymphadenopathy, hyperglobulinemia, and an increased total IgG, IgG1, IgG4 may suggest the …
View article: Outbreak of autoimmune disease in silicosis linked to artificial stone
Outbreak of autoimmune disease in silicosis linked to artificial stone Open
These cases underscore the strong link between silicosis and multiple distinct syndromes of autoimmune diseases. Vigilance is warranted for the recognition of autoimmune complications in persons with known silicosis; so too is consideratio…