Otto Laub
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View article: Symptoms, SARS-CoV-2 Antibodies, and Neutralization Capacity in a Cross Sectional-Population of German Children
Symptoms, SARS-CoV-2 Antibodies, and Neutralization Capacity in a Cross Sectional-Population of German Children Open
Background: Children and youth are affected rather mildly in the acute phase of COVID-19 and thus, SARS-CoV-2 infection infection may easily be overlooked. In the light of current discussions on the vaccinations of children it seems necess…
Mixed-methods evaluation of a structured primary care programme for children and adolescents with mental health problems (PrimA-QuO): a study protocol Open
Introduction More than 17% of German children and adolescents have clinically relevant mental health problems (MHP). Typically, general paediatricians are often the first contact for children with MHP, and referrals to specialised care ten…
Coronavirus antibody screening identifies children with mild to moderate courses of PMIS Open
Background: Children are affected rather mildly by the acute phase of COVID-19, but predominantly in children and youths, the potentially severe and life threatening pediatric multiorgan immune syndrome (PMIS) occurs later on. To identify …
“We’re in good hands there.” - Acceptance, barriers and facilitators of a primary care-based health coaching programme for children and adolescents with mental health problems: a qualitative study (PrimA-QuO) Open
Background 11.5 % of girls and 17.8 % of boys are affected by a mental health problem (MHP). The most prevalent problem areas are behavioural problems (girls/boys in %: 11.9/17.9), emotional problems (9.7/8.6) and hyperactivity problems (4…
“We’re in Good Hands There.” - Acceptance, Barriers and Facilitators of a Primary Care-based Health Coaching Programme for Children With Mental Health Problems: A Qualitative Study (Prima-quo) Open
Background: About 17 % of children aged 3-17 years are affected by a mental health problem (MHP). Office-based paediatricians are the first in line to be contacted. Nevertheless, even for less severely affected patients, referral rates to …
Yield of a Public Health Screening of Children for Islet Autoantibodies in Bavaria, Germany Open
Among children aged 2 to 5 years in Bavaria, Germany, a program of primary care-based screening showed an islet autoantibody prevalence of 0.31%. These findings may inform considerations of population-based screening of children for islet …
Nocturnal asthma is affected by genetic interactions between <i>RORA</i> and <i>NPSR1</i> Open
Background Neuropeptide S Receptor 1 ( NPSR1 ) and Retinoid Acid Receptor‐Related Orphan Receptor Alpha (RORA ) interact biologically, are both known candidate genes for asthma, and are involved in controlling circadian rhythm. Thus, we as…
Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: design and initial results of the Fr1da study Open
Introduction Type 1 diabetes can be diagnosed at an early presymptomatic stage by the detection of islet autoantibodies. The Fr1da study aims to assess whether early staging of type 1 diabetes (1) is feasible at a population-based level, (…