Keng‐Liang Ou
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View article: Facile Preparation of Graphene Oxide-Enhanced Highly Crystalline Polyglycolic Acid Under Low-Temperature Crystallization Using Tin(II) 2-Ethylhexanoate and Its Application in Biomaterials
Facile Preparation of Graphene Oxide-Enhanced Highly Crystalline Polyglycolic Acid Under Low-Temperature Crystallization Using Tin(II) 2-Ethylhexanoate and Its Application in Biomaterials Open
Polyglycolic acid (PGA), a biodegradable polymer with many potential applications, is primarily synthesized via the ring-opening polymerization of glycolide monomers. Here, the temperature sensitivity of the PGA crystallization kinetics is…
View article: Neurotoxic Effects of Perfluorooctanoic Acid (PFOA) on Mouse Cortical Neurons: A Quantitative Imaging Study
Neurotoxic Effects of Perfluorooctanoic Acid (PFOA) on Mouse Cortical Neurons: A Quantitative Imaging Study Open
View article: Cigarette Smoke-Induced Cell Morphology via Keyence and Zeiss Microscopy
Cigarette Smoke-Induced Cell Morphology via Keyence and Zeiss Microscopy Open
View article: Natural rhythmic speech activates network reorganization with frontal community enhancing communication efficiency in patients with intrinsic brain tumor
Natural rhythmic speech activates network reorganization with frontal community enhancing communication efficiency in patients with intrinsic brain tumor Open
Brain tumors provide unique insights into brain plasticity due to their slow growth compared to acute cerebrovascular diseases. Despite relying on sophisticated functional networks, patients with brain tumors exhibit minimal deficits in hi…
View article: Highly Compressible and Efficient CNT/rGO/PDMS Thermoelectric Generator Based on a 3D Sponge-Structured Network for Harvesting Energy from a Shoe Sole
Highly Compressible and Efficient CNT/rGO/PDMS Thermoelectric Generator Based on a 3D Sponge-Structured Network for Harvesting Energy from a Shoe Sole Open
View article: Repurposing Industrial Microscopy for Biology: Comparative Analysis of Cigarette Smoke-Induced Morphological Changes in Lung Epithelial Cells Using Keyence VHX-7000 and Zeiss Axiovert 200M
Repurposing Industrial Microscopy for Biology: Comparative Analysis of Cigarette Smoke-Induced Morphological Changes in Lung Epithelial Cells Using Keyence VHX-7000 and Zeiss Axiovert 200M Open
View article: Feasibility and Preliminary Efficacy of α–Calcium Sulfate Hemihydrate in Socket Preservation: Protocol for a Pilot Randomized Controlled Trial
Feasibility and Preliminary Efficacy of α–Calcium Sulfate Hemihydrate in Socket Preservation: Protocol for a Pilot Randomized Controlled Trial Open
Background Tooth extraction procedures often lead to bone resorption, which can have adverse effects on the dimensions of the alveolar ridge. Research has shown that socket preservation techniques using bone graft substitutes can effective…
View article: Empirical comparison of deep learning models for fNIRS pain decoding
Empirical comparison of deep learning models for fNIRS pain decoding Open
Introduction Pain assessment is extremely important in patients unable to communicate and it is often done by clinical judgement. However, assessing pain using observable indicators can be challenging for clinicians due to the subjective p…
View article: An innovative three-dimensional printed titanium implant with a biomimetic structure design for promoting osseointegration potential
An innovative three-dimensional printed titanium implant with a biomimetic structure design for promoting osseointegration potential Open
The present study aimed to investigate the surface characteristic, biocompatibility, and bone regeneration behavior of an innovative three-dimensional (3D) printed titanium (Ti) implant with a biomimetic cancellous bone-like spherical part…
View article: Investigation of Gas Layer Effects on Electrical Discharging to Improve Electrocautery Performance
Investigation of Gas Layer Effects on Electrical Discharging to Improve Electrocautery Performance Open
View article: Feasibility and Preliminary Efficacy of α–Calcium Sulfate Hemihydrate in Socket Preservation: Protocol for a Pilot Randomized Controlled Trial (Preprint)
Feasibility and Preliminary Efficacy of α–Calcium Sulfate Hemihydrate in Socket Preservation: Protocol for a Pilot Randomized Controlled Trial (Preprint) Open
BACKGROUND Tooth extraction procedures often lead to bone resorption, which can have adverse effects on the dimensions of the alveolar ridge. Research has shown that socket preservation techniques using bone graft substitutes can effectiv…
View article: An Innovative Bioactive Surface with Potential Hemocompatibility for Enhancing Osseointegration at Early-Stage Implantation
An Innovative Bioactive Surface with Potential Hemocompatibility for Enhancing Osseointegration at Early-Stage Implantation Open
View article: Fabrication of Biofunctional Oxide Layer with Potential Self-Antibacterial Performance on Titanium Implant for Promoting Osseointegration
Fabrication of Biofunctional Oxide Layer with Potential Self-Antibacterial Performance on Titanium Implant for Promoting Osseointegration Open
View article: Design of Three-Dimensional Bioprinting Bioinks Based on Biopolymers Scaffolds for Tissue Regeneration Applications
Design of Three-Dimensional Bioprinting Bioinks Based on Biopolymers Scaffolds for Tissue Regeneration Applications Open
View article: An innovative biomimetic porous bioceramic to facilitate bone tissue regeneration: microstructural characteristics, biocompatibility, and in vivo rabbit model evaluation
An innovative biomimetic porous bioceramic to facilitate bone tissue regeneration: microstructural characteristics, biocompatibility, and in vivo rabbit model evaluation Open
The present study aimed to develop a highly pure and crystalline beta-tricalcium phosphate (β-TCP) bone graft substitute using the propagated Scleractinian coral. The solid-state reaction followed by heat-treatment (1050 °C–1100 °C for 1 h…
View article: A Three-Dimensional Bioprinted Copolymer Scaffold with Biocompatibility and Structural Integrity for Potential Tissue Regeneration Applications
A Three-Dimensional Bioprinted Copolymer Scaffold with Biocompatibility and Structural Integrity for Potential Tissue Regeneration Applications Open
The present study was to investigate the rheological property, printability, and cell viability of alginate–gelatin composed hydrogels as a potential cell-laden bioink for three-dimensional (3D) bioprinting applications. The 2 g of sodium …
View article: In Vitro Evaluation of the Strength of Dentin Replacement in Complex Posterior Tooth Restoration
In Vitro Evaluation of the Strength of Dentin Replacement in Complex Posterior Tooth Restoration Open
Due to the increasing interest in direct restoration, there is a need to address the shortcomings of these restorations, mainly by increasing the longevity of complex direct restorations. The present study aimed to evaluate the tensile str…
View article: 2,3,5,4′-Tetrahydroxystilbene-2-O-β-glucoside Attenuates Reactive Oxygen Species-Dependent Inflammation and Apoptosis in Porphyromonas gingivalis-Infected Brain Endothelial Cells
2,3,5,4′-Tetrahydroxystilbene-2-O-β-glucoside Attenuates Reactive Oxygen Species-Dependent Inflammation and Apoptosis in Porphyromonas gingivalis-Infected Brain Endothelial Cells Open
We recently reported that the periodontopathic bacteria Porphyromonas gingivalis (P. gingivalis) initiates an inflammatory cascade that disrupts the balance of reactive oxygen species (ROS), resulting in apoptotic cell death in brain endot…
View article: Three-Dimensional Printing of a Hybrid Bioceramic and Biopolymer Porous Scaffold for Promoting Bone Regeneration Potential
Three-Dimensional Printing of a Hybrid Bioceramic and Biopolymer Porous Scaffold for Promoting Bone Regeneration Potential Open
In this study, we proposed a three-dimensional (3D) printed porous (termed as 3DPP) scaffold composed of bioceramic (beta-tricalcium phosphate (β-TCP)) and thermoreversible biopolymer (pluronic F-127 (PF127)) that may provide bone tissue i…
View article: Profile of vitamin D receptor gene polymorphism TaqI in patients with periodontitis
Profile of vitamin D receptor gene polymorphism TaqI in patients with periodontitis Open
The present study aimed to assess the incidence of the vitamin D receptor (VDR) gene polymorphism TaqI in patients with periodontitis, and the potential association of this polymorphism with the severity of the disease. This was a case-con…
View article: An Innovative Customized Biomimetic Hydrogel for Drug Screening Application Potential: Biocompatibility and Cell Invasion Ability
An Innovative Customized Biomimetic Hydrogel for Drug Screening Application Potential: Biocompatibility and Cell Invasion Ability Open
The ability of Pluronic F127 (PF127) conjugated with tetrapeptide Gly-Arg-Gly-Asp (GRGD) as a sequence of Arg-Gly-Asp (RGD) peptide to form the investigated potential hydrogel (hereafter referred to as 3DG bioformer (3BE)) to produce spher…
View article: A Promising Potential of Brown Algae Sargassum polycystum as Irreversible Hydrocolloid Impression Material
A Promising Potential of Brown Algae Sargassum polycystum as Irreversible Hydrocolloid Impression Material Open
This study aimed to investigate the potential use of brown algae Sargassum polycystum as irreversible hydrocolloid (alginate) impression material. Potassium alginate extracted from Sargassum polycystum was prepared in three different compo…
View article: Correction: Ou et al. Bone Healing and Regeneration Potential in Rabbit Cortical Defects Using an Innovative Bioceramic Bone Graft Substitute. Appl. Sci. 2020, 10, 6239
Correction: Ou et al. Bone Healing and Regeneration Potential in Rabbit Cortical Defects Using an Innovative Bioceramic Bone Graft Substitute. Appl. Sci. 2020, 10, 6239 Open
In the original publication, there was a mistake in Figure 2a as published [...]
View article: Biomimetic Ceramic Composite: Characterization, Cell Response, and In Vivo Biocompatibility
Biomimetic Ceramic Composite: Characterization, Cell Response, and In Vivo Biocompatibility Open
The present study aimed to synthesize biphasic calcium phosphate ceramics (CaPs) composed of β-tricalcium phosphate (β-TCP) and hydroxyapatite (HAp) from the propagated Scleractinian coral and dicalcium phosphate anhydrous using a solid-st…
View article: Porphyromonas gingivalis Induces Proinflammatory Cytokine Expression Leading to Apoptotic Death through the Oxidative Stress/NF-κB Pathway in Brain Endothelial Cells
Porphyromonas gingivalis Induces Proinflammatory Cytokine Expression Leading to Apoptotic Death through the Oxidative Stress/NF-κB Pathway in Brain Endothelial Cells Open
Porphyromonas gingivalis, a periodontal pathogen, has been proposed to cause blood vessel injury leading to cerebrovascular diseases such as stroke. Brain endothelial cells compose the blood-brain barrier that protects homeostasis of the c…
View article: Anodized Biomedical Stainless-Steel Mini-Implant for Rapid Recovery in a Rabbit Model
Anodized Biomedical Stainless-Steel Mini-Implant for Rapid Recovery in a Rabbit Model Open
The study aimed to analyze the recovery period of the anodized 316L biomedical stainless steel (BSS) mini-implant through its implantation on femur of rabbit model. The 316L BSS mini-implant was modified by an electrochemical anodization a…
View article: Vitamin D Receptor Gene Polymorphism as a Risk Factor for Chronic Periodontitis
Vitamin D Receptor Gene Polymorphism as a Risk Factor for Chronic Periodontitis Open
Background: The aim of this study was to investigate vitamin D receptor (VDR) gene polymorphism as a risk factor associated with chronic periodontitis (CP) and to determine the effect of VDR gene polymorphism on phenotypic CP. Methods: Thi…
View article: Surface Properties and Biocompatibility of Anodized Titanium with a Potential Pretreatment for Biomedical Applications
Surface Properties and Biocompatibility of Anodized Titanium with a Potential Pretreatment for Biomedical Applications Open
The effects of anodized titanium (Ti) with a potential hydrogen fluoride (HF) acid pretreatment through cathodization on the formation of nano-porous Ti dioxide (TiO2) layer were characterized using field-emission scanning electron microsc…
View article: An Innovative Bioceramic Bone Graft with Platelet-Rich Plasma for Rapid Bone Healing and Regeneration in a Rabbit Model
An Innovative Bioceramic Bone Graft with Platelet-Rich Plasma for Rapid Bone Healing and Regeneration in a Rabbit Model Open
This study aimed to investigate the effect of combining an innovative bioceramic α-calcium sulfate hemihydrate (α-CSH, CaSO4⋅0.5H2O) bone graft and platelet-rich plasma (PRP) to accelerate bone healing and regeneration in a rabbit model. T…
View article: The Potential of a Surface-Modified Titanium Implant with Tetrapeptide for Osseointegration Enhancement
The Potential of a Surface-Modified Titanium Implant with Tetrapeptide for Osseointegration Enhancement Open
In this study, the innovative dip-coating technique treated titanium (IDCT-Ti) implant with tetrapeptide Gly-Arg-Gly-Asp (GRGD) coating was investigated for its potential to enhance osseointegration. The L929 fibroblast cells were cultured…