Explanipedia

Lower Serum Kindlin-2 Levels are Associated with Liver Cirrhosis: A Preliminary Study Open

Özgür Altun, Olga Metin, Şengül Aydın Yoldemir, Okan Dikker, Yücel Arman , et al. · 2025

Background Kindlin-2 is a focal adhesion protein responsible for the adhesion of cells to each other and to the extracellular matrix. This property affects processes such as fibrosis and invasion in the cell. Recently, kindlin-2 has also b…

POS0646 THE DEVELOPMENT OF AVASCULAR NECROSIS IN DIFFERENT RHEUMATOLOGIC DISEASES AND ITS ASSOCIATION WITH CUMULATIVE CORTICOSTEROID DOSE: A RETROSPECTIVE ANALYSIS OF A REAL-WORLD EVIDENCE Open

Rabia Deniz, Şule Gök, Celal Yavuz, Çağrı Erdim, Özgür Altun , et al. · 2025

ABS1133 INDICATIONS, EFFICACY, AND SAFETY OF CANAKINUMAB: REAL LIFE EXPERIENCE OF A TERTIARY RHEUMATOLOGY CLINIC Open

R. Deniz, Özgür Altun, Şule Gök, Celal Yavuz, H.K. Yerişenoğlu Demir , et al. · 2025

The Association Between Depression and Antidiabetic Treatments in Type 2 Diabetes Patients with Both Good and Poor Glycemic Control Open

Perihan Özkan Gümüşkaya, Özgür Altun, Emine Yıldırım, Nur Karakutuk Yuztas, Neslihan Özsoy , et al. · 2025

Background: Much research has demonstrated that there is a relation between depression and chronic diseases. Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases, and it is an expanding global health problem. This stu…

Clinical Value of Circulating Angiopoietin-like Protein 8/Betatrophin Levels in Patients with Acute Pancreatitis Open

Perihan Özkan Gümüşkaya, Emine Yıldırım, Özgür Altun, Hafize Uzun · 2025

Background and Objectives: Acute pancreatitis (AP) is an inflammatory disorder of the pancreas, with severe cases linked to a higher mortality rate. The prognosis of AP is influenced by factors such as necrosis, secondary infections, and o…

Pediatric perianal Crohn’s disease without luminal inflammation Open

Mary Augustine, KL Williams, Özgür Altun, David A. Gremse · 2024

Alagille syndrome in a 4 week old infant with JAG1 mutation Open

IO Udoete, Z Nizami, Özgür Altun · 2024

O Nível de Endocan Sérico pode ser Usado como Biomarcador para Prever Aterosclerose Subclínica em Pacientes Pré-Diabéticos? Open

Yücel Arman, Adem Atıcı, Özgür Altun, Remzi Sarıkaya, Sengül Aydin Yoldemir , et al. · 2022

Carotid intima media thickness was found to be high and the serum endocan level was low in patients with prediabetes. Decreased serum endocan levels in patients with prediabetes may be a contributing factor to atherosclerosis formation mec…

The Changes In The AntiHBs Values Following COVID-19 Pneumonia Open

Perihan ÖZKAN GÜMÜŞKAYA, Özgür Altun, Nur Karakütük Yüztaş, Neslihan Özsoy, Gülten Aydın Tutak , et al. · 2022

Background/aim: We aimed to determine if there is a decrease in antiHBS titer below the protective value during Coronavirus-19 disease (COVID-19). Materials and methods: A prospective study was made of 67 patients who had positive antiHbs …

The Role of Triglyceride-HDL Ratio and Triglyceride-glucose Index in Estimating Glycemic Control in Patients with Type 2 Diabetes Mellitus Open

Özgür Altun, Semih Kalyon · 2022

Objective: Our aim is to evaluate blood glucose regulation in patients with diabetes using the triglyceride glucose index and the triglyceride to high density lipoprotein (HDL) ratio. Materials and Methods:The data of our retrospective stu…

Can the Serum Endocan Level Be Used as a Biomarker to Predict Subclinical Atherosclerosis in Patients with Prediabetes? Open

Yücel Arman, Adem Atıcı, Özgür Altun, Remzi Sarıkaya, Sengül Aydin Yoldemir , et al. · 2022

Background Patients with prediabetes have an increased risk of atherosclerotic cardiovascular disease; therefore, early detection is important. Objective The present study aimed to reveal the usability of serum endocan levels as a biomarke…

Can the Serum Endocan Level Be Used as a Biomarker to Predict Subclinical Atherosclerosis in Patients with Prediabetes? Open

Yücel Arman, Adem Atıcı, Özgür Altun, Remzi Sarıkaya, Sengül Aydin Yoldemir , et al. · 2022

Background Patients with prediabetes have an increased risk of atherosclerotic cardiovascular disease; therefore, early detection is important. Objective The present study aimed to reveal the usability of serum endocan levels as a biomarke…

Serum galectin-3 levels and vitamin D relationship in heart failure Open

Mustafa Özcan, Murat Akarsu, Şengül AYDIN YOLDEMİR, Özgür Altun, Orkide Kutlu , et al. · 2021

Background/Aim: Heart failure is an important health problem with an increasing incidence in the world and poor prognosis. Galectin-3 is associated with progressive fibrosis, an underlying pathology of heart failure, just as vitamin D defi…

Tip 2 Diyabetes Mellitus, Fibromiyalji Sendromu ve Serum Magnezyum İlişkisi Open

Özgür Altun, Şengül AYDIN YOLDEMİR · 2021

Amaç: Fibromiyalji sendromu (FMS), temel olarak kronik yaygın ağrının olduğu, psikolojik ve somatik yakınmaların eşlik ettiği, nedeni bilinmeyen bir hastalıktır. Tip 2 diyabetes mellitus ve hipomagnezemide de kronik kas ağrıları, nöromüskü…

The relationship between sarcopenia and nesfatin-1 and ghrelin levels in patients with chronic obstructive pulmonary disease Open

Gülay Daşdemir İlkhan, Selay ARSLAN, Yücel Arman, Özgür Altun, Hakan Çelikhisar , et al. · 2021

Background and Aim: In this study, we aimed to investigate the relationship between the levels of adipocytokines anorexigenic nesfatin-1 and orexigenic ghrelin levels and body mass index (BMI), muscle mass, muscle strength and sarcopenia i…

The association of laminin levels with insulin resistance and non-alcoholic hepatosteatosis Open

Özgür Altun, Yücel Arman, Şengül Aydın Yoldemir, Ayşe Pala, Perihan Özkan Gümüşkaya , et al. · 2021

Background Laminin, one of the largest glycoproteins of the basement membrane, is an important component of the extracellular matrix. Functions of the basement membrane include regulation of cell signaling behaviors and structural support.…

Correlation of glycemic regulation and endotrophin in patients with type 2 Diabetes; pilot study Open

Şengül Aydın Yoldemir, Yücel Arman, Murat Akarsu, Özgür Altun, Mustafa Özcan , et al. · 2021

Relationships among oncostatin M, insulin resistance, and chronic inflammation: a pilot study Open

Murat Akarsu, Mehmet Hursçitoglu, Zeki Toprak, Sengül Aydin Yoldemir, Özgür Altun , et al. · 2021

For the first time in Colombia, the efficacy of sorafenib was evaluated in patients with advanced and progressive thyroid carcinoma refractory to radioactive iodine, with an efficacy and a safety profile similar to those previously reporte…

Apelin: A new biomarker in fatty liver disease Open

Semih Kalyon, Özgür Altun, Ayşe Pala, Tufan Tükek · 2021

Apelin is a peptide known for its insulin-sensitizing effect. This study aimed to examine the relationship between apelin and fatty liver disease. Non-diabetic patients were evaluated by ultrasound in this prospective, single-center, case-…

Correlation of Glycemic Regulation and Endotrophin in Patients with Type 2 Diabetes; Pilot Study Open

Şengül Aydın Yoldemir, Yücel Arman, Murat Akarsu, Özgür Altun, Mustafa Özcan , et al. · 2020

Background: Endotrophin is one of the extracellular matrix proteins secreted by adipose tissue. In this study, we aimed to investigate the effects of changes in blood glucose levels on serum endotropin levels secreted by adipose tissue and…

Pulmonary Manifestations of Crohn's Disease in a Pediatric Patient Open

C.G. Cherian, Özgür Altun, Danya Rosen, Marie E. Egan · 2020

Relationships among oncostatin M, insulin resistance, and chronic inflammation: a pilot study Open

Murat Akarsu, Mehmet Hurşitoğlu, Zeki Toprak, Şengül Aydın Yoldemir, Özgür Altun , et al. · 2020

Objective Activated macrophages (M1-type macrophages) in adipose tissue secrete many proinflammatory cytokines that induce insulin resistance (IR). Oncostatin M (OSM), a member of the interleukin-6 (IL-6) family of Gp130 cytokines, plays a…

The importance of platelet count, PDW and MPV value in the follow-up of patients with helicobacter pylori eradication Open

Özgür Altun · 2020

INTRODUCTION[|]Helicobacter pylori infection is common all over the world. The present study aims to have platelet indices; to examine the role of platelet count, mean platelet volume (MPV) and platelet distribution width (PDW) as useful, …

The Relationship Between Insulin Resistance and Serum Preptin Level Open

Şengül Aydın Yoldemir, Özgür Altun · 2019

Giriş: Preptin, proinsülin benzeri büyüme faktörü-II'nin e-peptidinden türetilir. Adacık β hücre grenüllerinde bulunur ve glikoza yanıt olarak insülin ile birlikte salgılanır. Daha önce yapılan çalışmalarda, preptinin glikoz ve lipid metab…

Relationships among oncostatin M, insulin resistance, and chronic inflammation: a pilot study Open

Murat Akarsu, Mehmet Hurşitoğlu, Zeki Toprak, Şengül Aydın Yoldemir, Özgür Altun , et al. · 2019

Objective Activated macrophages (M1-type macrophages) in adipose tissue secrete many proinflammatory cytokines that induce insulin resistance (IR). Oncostatin M (OSM), a member of the interleukin-6 (IL-6) family of Gp130 cytokines, plays a…

Reply to the Letter to the Editor “Adropin: Connection between Nonalcoholic Fatty Liver Disease and Coronary Artery Disease” Open

Orkide Kutlu, Özgür Altun, Okan Dikker, Hanife Şerife Aktaş, Neslihan Özsoy , et al. · 2019

The effects of overt hypothyroidism on adipose tissue and serum betatrophin levels Open

Murat Akarsu, Şengül Aydın Yoldemir, Özgür Altun, Okan Dikker, Mustafa Özcan , et al. · 2019

Aim: Betatrophin, also known as angiopoietin-like peptide-8, is an adipokine in glycoprotein structure synthesized from adipose tissue and liver. Betatrophin plays a role in fat and energy metabolism by inhibiting lipoprotein lipase, the k…

The relationship between sarcopenia and cognitive dysfunction in bladder tumor patients Open

Semih Kalyon, Perihan Özkan Gümüşkaya, Neslihan Özsoy, Mustafa Özcan, Şengül AYDIN YOLDEMİR , et al. · 2019

Aim: There is no study in the literature to show whether there is a negative effect of sarcopenia on cognitive functions in patients over 65 years of age in the early postoperative period, who were operated under general anesthesia. The ai…

The relationship of serum galectin-3 levels with obesity and insulin resistance Open

Özgür Altun, Okan Dikker, Murat Akarsu, Yücel Arman, Şengül Aydın Yoldemir , et al. · 2019

Aim: Galectin-3 affects inflammation, cell adhesion, proliferation, differentiation and angiogenesis. Upon examining the pathogenesis of obesity and functions of galectin-3, we thought that galectin-3 may play a significant role in obese p…

Serum Adropin Levels Are Reduced in Adult Patients with Nonalcoholic Fatty Liver Disease Open

Orkide Kutlu, Özgür Altun, Okan Dikker, Hanife Şerife Aktaş, Neslihan Özsoy , et al. · 2019

Objectives: Adropin is a novel marker of metabolic syndrome and insulin resistance. The aim of this study was to explore the association of serum adropin levels with hepatosteatosis among adult patients. Materials and M…

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