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Evaluation of Thyroid Functions After Radiotherapy in Primary Head and Neck Malignancies without Surgery Open
Aim: In this study, it was aimed to investigate thyroid dysfunction in patients who underwent radiotherapy due to primary head and neck malignancy. Material and Methods: The study was carried out between January 1, 2008 and January 31, 201…
Radioprotective Effects of Annona Muricata Leaf Extract in the Spinal Cord Open
Objective: The spinal cord is often involved in radiotherapy to treat malignancies and is considered as one of the most critical dose-limiting organs. Histopathological changes of radiation-induced spinal cord injury include gliosis, demye…
Annona Muricata Yaprak Ekstratının Spinal Korddaki Radyoprotektif Etkileri ve Histopatolojik Sonuçları Open
Amaç: Radyoterapi (RT), primer ve metastatik tümörler için önemli bir kanser tedavisidir. Çok sayıda çalışma, DNA'nın, l ipitlerin veproteinlerin, iyonize radyasyon (IR) tarafından indüklenen serbest radikaller tarafından saldırıya uğ…
Clinical comprehensive and experimental assessment of the radioprotective effect of <i>Annona muricata</i> leaf extract to prevent cellular damage in the ileum tissue Open
We report the radioprotective attitude of Annona muricata (AM) leaf extract as antioxidant material to prevent cellular damage in the ileum tissue. The protective effects of an ethyl acetate extract of AM leaves are comprehensively investi…
A focusing study on radioprotective and antioxidant effects of <i>Annona muricata</i> leaf extract in the circulation and liver tissue: Clinical and experimental studies Open
Objectives This study investigates the effect of Annona muricata (AM) leaf extract against irradiation-induced damage by the evaluation of hepatic tissue and the levels of oxidative and inflammatory stress in the circulation. Methods An ex…
The Neuroprotective and Anti-Inflammatory Effects of Annona Muricata (Graviola) on Radiation-Induced Rat Sciatic Nerve Injury. Open
Background: In radiotherapy (RT) exposure area, normal tissues are also affected that may cause serious complications in the patients. This study aimed to evaluate Annona muricata’s radioprotective effects on sciatic nerve injury due to io…
PET/CT Findings of a Patient with Striped Muscle Metastasis of Invasive Breast Carcinoma Open
A 37-year-old female with a history of invasive breast carcinoma was referred to our department for an 18flor-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography whole-body scan. An intense 18F-FDG uptake in strip…
Epidemiology, Treatment Options and Survival Analysis of Glioblastoma Multiforme: A Retrospective Single Center Study Open
Aim: Glioblastoma multiforme (GBM) is the most common of primary brain tumors. Although there are many clinical and experimental studies about its treatment; options for treatment of GBM have not changed much. Our study was planned to exam…
A Comparison Between Modified Radical Mastectomy and Breast-Conserving Surgery Concerning the Quality of Life in Patients with Breast Cancer Under 50 Years of Age Open
surgery (BCS) to those having undergone modified radical mastectomy (MRM). Material and Methods: Forty-four BCS and 27 MRM patients have been included in this retrospective study. All patients have completed adjuvant chemotherapies and rad…
Changes in lung perfusion scintigraphy and pulmonary function tests in irradiated breast cancer patients Open
Objectives: To investigate the utility of quantitative lung perfusion scintigraphy and pulmonary function tests (PFTs) in the assessment of radiation-induced lung injury. Methods: Forty-three breast cancer patients underwent lung perfusion…
Dosimetric comparison of organs at risk in 5 different radiotherapy plans in patients with preoperatively irradiated rectal cancer Open
Background: Intensity-modulated radiotherapy (IMRT) is a widely used irradiation technique in rectal cancer patients. We aimed to compare 4 different IMRT plans with 3-dimensional conformal radiotherapy (3D-CRT) considering organs at risk …
Long-term Changes in Creatinine Clearance and Renal Parenchymal Volume with Dosimetric Parameters in Gastric Cancer Patients with Treated Chemoradiotherapy Open
The objective of the study was to evaluate the long-term impact of adjuvant chemoradiotherapy (CRT) on renal function through the creatinine clearance (Ccr) and renal parenchymal (RPR) volume and to compare the results with dose-volume his…
Protective effects of hesperidin on ionizing radiation-induced liver damage Open
Aim: Liver is mostly exposed to radiation during radiotherapy to the upper abdomen, the right lobe of the lung, distal esophagus tumors or total body irradiation. Radiation may lead to cellular damage, and clinical and laboratory findings …
Neuroprotective effects of Quercetin on radiation-induced brain injury in rats Open
Extensive research has been focused on radiation-induced brain injury. Animal and human studies have shown that flavonoids have remarkable toxicological profiles. This study aims to investigate the neuroprotective effects of quercetin in a…
Protective Effects of Quercetin on Intestinal Damage Caused by Ionizing Radiation Open
Aim: The aim of this study was to evaluate the protective use of quercetin in a rat model of radiation-induced enteritis and colitis. Methods: Twenty four adult rats were randomly divided into four groups. Group SHAM was given only physiol…