P. Balaram
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View article: Formylation of His Residues at Position 2 in Peptide <i>b</i> Ions due to Noncanonical C <sup>α</sup> ‐CO Bond Cleavage: Assignment of the <i>m/z</i> 166 Product Ion in Proteome Data
Formylation of His Residues at Position 2 in Peptide <i>b</i> Ions due to Noncanonical C <sup>α</sup> ‐CO Bond Cleavage: Assignment of the <i>m/z</i> 166 Product Ion in Proteome Data Open
Rationale The low m/z region (less than 300) in the MS/MS spectra of peptides is rich with product ions arising from neutral losses and noncanonical bond cleavages, resulting from the gas‐phase chemistry of low mass b n / y n ions containi…
View article: The longer transmembrane helices of class I viral fusion proteins may facilitate viral fusion
The longer transmembrane helices of class I viral fusion proteins may facilitate viral fusion Open
The viral envelope-resident viral fusion proteins (VFPs) fuse the envelope with the host cell membrane, which allows virus entry into host cells. The homotrimeric class I VFPs (cI-VFPs) are anchored to the envelope by three single-pass tra…
View article: Albumin Oxidation and Albumin Glycation Discordance During Type 2 Diabetes Therapy: Biological and Clinical Implications
Albumin Oxidation and Albumin Glycation Discordance During Type 2 Diabetes Therapy: Biological and Clinical Implications Open
Aims: Cys34 albumin redox modifications (reversible "cysteinylation" and irreversible "di/trioxidation"), besides being just oxidative stress biomarkers, may have primary pathogenetic roles to initiate and/or aggravate cell, …
View article: William L. Mock and Cucurbituril: The Resurrection of the Behrend Paper of 1905
William L. Mock and Cucurbituril: The Resurrection of the Behrend Paper of 1905 Open
In 1905, Robert Behrend reported the preparation of a substance that remained a dry powder despite absorbing water and that had the ability to absorb dyes from solution. Over seven decades later, William L. Mock repeated the Behrend synthe…
View article: Revisiting the burden borne by fumarase: enzymatic hydration of an olefin
Revisiting the burden borne by fumarase: enzymatic hydration of an olefin Open
Fumarate hydratase (FH) is a remarkable catalyst that decreases the free energy of the catalyzed reaction by 30 kcal mol −1 , much larger than most exceptional enzymes with extraordinary catalytic rates. Two classes of FH are observed in n…
View article: CCDC 971416: Experimental Crystal Structure Determination
CCDC 971416: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 971418: Experimental Crystal Structure Determination
CCDC 971418: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 971417: Experimental Crystal Structure Determination
CCDC 971417: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Bijoor Sanjiva Rao, morellin and early natural products chemistry in India
Bijoor Sanjiva Rao, morellin and early natural products chemistry in India Open
View article: Gopinath Kartha and the Birth of Chemical Crystallography in India
Gopinath Kartha and the Birth of Chemical Crystallography in India Open
View article: Sequence of the SARS-CoV-2 spike transmembrane domain makes it inherently dynamic
Sequence of the SARS-CoV-2 spike transmembrane domain makes it inherently dynamic Open
The homotrimeric SARS-CoV-2 spike protein enables viral infection by mediating the fusion of the viral envelope with the host membrane. The spike protein is anchored to the SARS-CoV-2 envelope by its transmembrane domain (TMD), which is co…
View article: Structural basis for the hyperthermostability of an archaeal glutaminase induced by post-translational succinimide formation
Structural basis for the hyperthermostability of an archaeal glutaminase induced by post-translational succinimide formation Open
Stability of proteins from hyperthermophiles enabled by reduction of conformational flexibility is realized through various mechanisms. Presence of a stable, hydrolysis-resistant succinimide arising from cyclization of the side chains of a…
View article: CCDC 1560167: Experimental Crystal Structure Determination
CCDC 1560167: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1560168: Experimental Crystal Structure Determination
CCDC 1560168: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1560170: Experimental Crystal Structure Determination
CCDC 1560170: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1560169: Experimental Crystal Structure Determination
CCDC 1560169: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1560166: Experimental Crystal Structure Determination
CCDC 1560166: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1007207: Experimental Crystal Structure Determination
CCDC 1007207: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1007206: Experimental Crystal Structure Determination
CCDC 1007206: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
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View article: Unexpected functional implication of a stable succinimide in the structural stability of Methanocaldococcus jannaschii glutaminase
Unexpected functional implication of a stable succinimide in the structural stability of Methanocaldococcus jannaschii glutaminase Open
View article: Issue information ‐ Copyright and Table of Contents
Issue information ‐ Copyright and Table of Contents Open
View article: Issue information ‐ Copyright and Table of Contents
Issue information ‐ Copyright and Table of Contents Open
View article: Issue information ‐ Copyright and Table of Contents
Issue information ‐ Copyright and Table of Contents Open
View article: CCDC 662234: Experimental Crystal Structure Determination
CCDC 662234: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
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Issue Information Open
View article: Issue Information
Issue Information Open
View article: Probing the role of highly conserved residues in triosephosphate isomerase – analysis of site specific mutants at positions 64 and 75 in the <i>Plasmodial</i> enzyme
Probing the role of highly conserved residues in triosephosphate isomerase – analysis of site specific mutants at positions 64 and 75 in the <i>Plasmodial</i> enzyme Open
Highly conserved residues in enzymes are often found to be clustered close to active sites, suggesting that functional constraints dictate the nature of amino acid residues accommodated at these sites. Using the Plasmodium falciparum trios…
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View article: Issue Information
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