Paolo Boffetta
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View article: Effectiveness of Occupational Health Promotion Programs on Cardiometabolic risk factors: A Systematic Review and Three-Level Meta-Analysis
Effectiveness of Occupational Health Promotion Programs on Cardiometabolic risk factors: A Systematic Review and Three-Level Meta-Analysis Open
Background: This study aimed to evaluate the effectiveness of workplace-based health promotion programs targeting cardiometabolic risk factors. Methods: We conducted a systematic review and three-level random-effects meta-analysis followin…
View article: Esophageal and Gastric Cancer Incidence and Mortality Trends in Norway, 1993–2022: A Registry-Based Study
Esophageal and Gastric Cancer Incidence and Mortality Trends in Norway, 1993–2022: A Registry-Based Study Open
The incidence and mortality of esophageal AC has increased in Norway during the last decades, most pronounced in men, ages ≥70 years. The rates of SCCs decreased, although trends differed between sex and age groups. The incidence and morta…
View article: Expanding Cancer Prevention: Strategies Integrated into Occupational Health Surveillance
Expanding Cancer Prevention: Strategies Integrated into Occupational Health Surveillance Open
Participation in cancer prevention programs is suboptimal. Socioeconomic backgrounds play a role in cancer awareness and prevention programs. We conducted a narrative review, summarizing the evidence on the integration of cancer prevention…
View article: Occupational-Related Exposure to Diesel Exhaust and Kidney Cancer: Systematic Review and Meta-Analysis of Cohort Studies
Occupational-Related Exposure to Diesel Exhaust and Kidney Cancer: Systematic Review and Meta-Analysis of Cohort Studies Open
Background: The association between diesel exhaust and cancer other than the lung is not well established. We aimed to conduct a systematic review and meta-analysis on the association between diesel and kidney cancer in workers.Methods: Tw…
View article: Lung Cancer Incidence After September 11, 2001, Among World Trade Center Responders
Lung Cancer Incidence After September 11, 2001, Among World Trade Center Responders Open
Importance Responders involved in rescue and recovery operations after the collapse of the World Trade Center (WTC) on September 11, 2001, were exposed to airborne carcinogens. Objectives To examine the incidence of lung cancer after the W…
View article: Genetically determined body mass index is associated with diffuse large B‐cell lymphoma in polygenic and Mendelian randomization analyses
Genetically determined body mass index is associated with diffuse large B‐cell lymphoma in polygenic and Mendelian randomization analyses Open
Obesity has been associated with non‐Hodgkin lymphoma (NHL), but the evidence is inconclusive. We examined the association between genetically determined adiposity and four common NHL subtypes: diffuse large B‐cell lymphoma (DLBCL), follic…
View article: Body mass index and gastric cancer risk: results from the Stomach Cancer Pooling Project Consortium
Body mass index and gastric cancer risk: results from the Stomach Cancer Pooling Project Consortium Open
Background Body mass index (BMI) has been associated with gastric cancer (GC), though results are conflicting regarding the GC subsites of cardia and non-cardia. This study aims to evaluate the associations between BMI and GC risk, focusin…
View article: Supplementary Table S3 from Associations between Opium Route of Use and Exposure to Polycyclic Aromatic Hydrocarbons as Potential Carcinogenicity Mechanism
Supplementary Table S3 from Associations between Opium Route of Use and Exposure to Polycyclic Aromatic Hydrocarbons as Potential Carcinogenicity Mechanism Open
Table S3 shows the geometric means of PAH biomarker concentrations and 95% confidence intervals, stratified by tertiles of recency of use and sorted by route of opium use. P-values from linear trend tests across the tertiles of recency are…
View article: Supplementary Table S1 from Associations between Opium Route of Use and Exposure to Polycyclic Aromatic Hydrocarbons as Potential Carcinogenicity Mechanism
Supplementary Table S1 from Associations between Opium Route of Use and Exposure to Polycyclic Aromatic Hydrocarbons as Potential Carcinogenicity Mechanism Open
Table S1 shows the geometric means and 95% confidence intervals of PAH biomarker concentrations, adjusted for demographic factors, recency and intensity of use and opium type, stratified by route of opium use. P-values from tests of differ…
View article: Data from Associations between Opium Route of Use and Exposure to Polycyclic Aromatic Hydrocarbons as Potential Carcinogenicity Mechanism
Data from Associations between Opium Route of Use and Exposure to Polycyclic Aromatic Hydrocarbons as Potential Carcinogenicity Mechanism Open
Background:Opium consumption is carcinogenic, but the impact of the route of use (smoking vs. ingestion) on exposure to potential proposed carcinogens is understudied.Methods:As a nested study within the Golestan Cohort Study, we gathered …
View article: Supplementary Table S2 from Associations between Opium Route of Use and Exposure to Polycyclic Aromatic Hydrocarbons as Potential Carcinogenicity Mechanism
Supplementary Table S2 from Associations between Opium Route of Use and Exposure to Polycyclic Aromatic Hydrocarbons as Potential Carcinogenicity Mechanism Open
Table S2 shows the coefficients, 95% confidence intervals, and p-values from multivariate linear regression model, with PAH biomarker concentrations as dependent variables and route or type of use as the main independent variable. Models w…
View article: Per- and poly-fluoroalkyl substances (PFAS) Exposure and risk of bladder and prostate cancers: A systematic review and meta-analysis
Per- and poly-fluoroalkyl substances (PFAS) Exposure and risk of bladder and prostate cancers: A systematic review and meta-analysis Open
Objectives: PFASs are synthetic chemicals that humans may be exposed to through workplace or the environment. Previous studies have suggested a carcinogenic effect. In our review, we investigated the association between PFAS exposure and r…
View article: Antibody Kinetics of Immunological Memory in SARS-CoV-2-Vaccinated Healthcare Workers—The ORCHESTRA Project
Antibody Kinetics of Immunological Memory in SARS-CoV-2-Vaccinated Healthcare Workers—The ORCHESTRA Project Open
Background/Objectives: This study examines the longitudinal dynamics of anti-nucleocapsid (anti-N) and anti-spike (anti-S) antibody responses to SARS-CoV-2 infection and mRNA vaccination based on 81,878 serum samples from 23,616 healthcare…
View article: An Updated Mortality Study of Beryllium Workers, 1925–2020
An Updated Mortality Study of Beryllium Workers, 1925–2020 Open
Objective Update and expand a cohort of beryllium workers, to examine risks associated with beryllium solubility and mortality from lung cancer, all cancers, all causes, as well as other neoplasms (kidney, bladder, central nervous system) …
View article: Evaluating the breast cancer quality of care indicators in Iran; multicenter study
Evaluating the breast cancer quality of care indicators in Iran; multicenter study Open
The defined indicators had a value lower than the suggested standards by EUSOMA. This study's results highlight important clues for intervention in improving breast cancer outcomes in Iran and other low-and middle-income countries.
View article: Household fuel use and kidney disease-related mortality: the Golestan Cohort Study
Household fuel use and kidney disease-related mortality: the Golestan Cohort Study Open
The findings of our study suggest that burning biomass for household purposes with poor ventilation is associated with kidney disease-related mortality. Interventions fostering the adoption of chimney-equipped stoves should be considered t…
View article: Association Between Cardiometabolic Multimorbidity and 15-year Mortality in the Asia Cohort Consortium
Association Between Cardiometabolic Multimorbidity and 15-year Mortality in the Asia Cohort Consortium Open
These findings highlight the differential impacts of individual cardiometabolic diseases and their combinations on mortality risks. Stroke and diabetes were associated with the highest risks for all-cause and cardiovascular mortality, unde…
View article: Supplementary table 2 from Reversal of Head and Neck Cancer Risk after the Cessation of Use of Smokeless Tobacco and Betel Quid Use: Meta-Analysis
Supplementary table 2 from Reversal of Head and Neck Cancer Risk after the Cessation of Use of Smokeless Tobacco and Betel Quid Use: Meta-Analysis Open
Selected characteristics of the studies included in the review and meta-analysis.
View article: Supplementary table 1 from Reversal of Head and Neck Cancer Risk after the Cessation of Use of Smokeless Tobacco and Betel Quid Use: Meta-Analysis
Supplementary table 1 from Reversal of Head and Neck Cancer Risk after the Cessation of Use of Smokeless Tobacco and Betel Quid Use: Meta-Analysis Open
Detailed search strategy used on the different databases
View article: Supplementary Methods 1 from Reversal of Head and Neck Cancer Risk after the Cessation of Use of Smokeless Tobacco and Betel Quid Use: Meta-Analysis
Supplementary Methods 1 from Reversal of Head and Neck Cancer Risk after the Cessation of Use of Smokeless Tobacco and Betel Quid Use: Meta-Analysis Open
Supplementary Methods 1: The detailed information of NEWCASTLE - OTTAWA QUALITY ASSESSMENT SCALE
View article: Data from Reversal of Head and Neck Cancer Risk after the Cessation of Use of Smokeless Tobacco and Betel Quid Use: Meta-Analysis
Data from Reversal of Head and Neck Cancer Risk after the Cessation of Use of Smokeless Tobacco and Betel Quid Use: Meta-Analysis Open
The use of smokeless tobacco and betel quid is a significant risk factor for head and neck cancer, posing a major global public health concern. This meta-analysis evaluates the impact of cessation of the use of these products on head and n…
View article: Welding Fumes Exposure and the Risk of Head and Neck and Gastrointestinal Cancer: A Systematic Review and Meta-Analysis
Welding Fumes Exposure and the Risk of Head and Neck and Gastrointestinal Cancer: A Systematic Review and Meta-Analysis Open
Background: The association between welding fumes and cancers other than lung cancer remains undefined. We conducted a systematic review and meta-analysis on occupational exposure to welding fumes and the risk of head and neck cancer (HN, …
View article: Fish consumption and gastric cancer within the Stomach cancer Pooling (StoP) Project
Fish consumption and gastric cancer within the Stomach cancer Pooling (StoP) Project Open
Gastric cancer is among the most common cancer and cause of cancer death. We conducted a meta-analysis of 25 case-control studies from the Stomach cancer Pooling Project to assess the association between fish or canned fish consumption and…
View article: Digital tools’ effectiveness on physical activity practice in healthy children and adolescents: an umbrella review within the DigitAl Lifelong pREvention (DARE) project (Preprint)
Digital tools’ effectiveness on physical activity practice in healthy children and adolescents: an umbrella review within the DigitAl Lifelong pREvention (DARE) project (Preprint) Open
BACKGROUND Children and adolescents do not meet the current guidelines for physical activity (PA). Interventions aimed at increasing their PA have been worldwide implemented through the use of different digital tools, but a clearer view o…
View article: Supplementary Table 3 from Reproductive and Hormonal Factors and Thyroid Cancer Risk: Pooled Analysis of Prospective Cohort Studies in the Asia Cohort Consortium
Supplementary Table 3 from Reproductive and Hormonal Factors and Thyroid Cancer Risk: Pooled Analysis of Prospective Cohort Studies in the Asia Cohort Consortium Open
Supplementary Table 3: Pooled relative risks for recategorized age at menarche and age at menopause & incident thyroid cancer risk, Overall and papillary type
View article: Supplementary Table 2 from Reproductive and Hormonal Factors and Thyroid Cancer Risk: Pooled Analysis of Prospective Cohort Studies in the Asia Cohort Consortium
Supplementary Table 2 from Reproductive and Hormonal Factors and Thyroid Cancer Risk: Pooled Analysis of Prospective Cohort Studies in the Asia Cohort Consortium Open
Supplementary Table 2: Distribution of total cases according to histology according to participating cohorts
View article: Supplementary Table 4 from Reproductive and Hormonal Factors and Thyroid Cancer Risk: Pooled Analysis of Prospective Cohort Studies in the Asia Cohort Consortium
Supplementary Table 4 from Reproductive and Hormonal Factors and Thyroid Cancer Risk: Pooled Analysis of Prospective Cohort Studies in the Asia Cohort Consortium Open
Supplementary Table 4: Stratified analyses of the Association between reproductive factors and the risk of thyroid cancer by country and birth years
View article: Supplementary Figure 6 from Reproductive and Hormonal Factors and Thyroid Cancer Risk: Pooled Analysis of Prospective Cohort Studies in the Asia Cohort Consortium
Supplementary Figure 6 from Reproductive and Hormonal Factors and Thyroid Cancer Risk: Pooled Analysis of Prospective Cohort Studies in the Asia Cohort Consortium Open
Supplementary Figure 6: Forest plot of pooled hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between reproductive factors and thyroid cancer risk, by age of diagnosis in the Asia Cohort Consortium. The Pooled Ha…